SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3sll'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EII_A_RTLA135_0
(CELLULAR
RETINOL-BINDING
PROTEIN II)		 3sll PROBABLE ENOYL-COA
HYDRATASE/ISOMERASE
(Mycobacteroides
abscessus) 		5 / 12 ALA A 121
ILE A  13
LEU A  15
LEU A  18
LEU A 194
 None
 1.31A 1eiiA-3sllA:
undetectable		 1eiiA-3sllA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_G_ACTG3009_0
(BETA-CARBONIC
ANHYDRASE)		 3sll PROBABLE ENOYL-COA
HYDRATASE/ISOMERASE
(Mycobacteroides
abscessus) 		4 / 5 GLY A 212
LEU A 215
THR A 216
VAL A 243
 None
 0.83A 1ekjF-3sllA:
undetectable
1ekjG-3sllA:
undetectable		 1ekjF-3sllA:
20.00
1ekjG-3sllA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_B_SWFB502_1
(CYTOCHROME P450 2C9)		 3sll PROBABLE ENOYL-COA
HYDRATASE/ISOMERASE
(Mycobacteroides
abscessus) 		5 / 12 ARG A 127
ILE A 109
ALA A 113
LEU A 122
LEU A  98
 GOL  A 270 (-3.0A)
None
None
GOL  A 270 (-4.6A)
None
 0.84A 1og5B-3sllA:
undetectable		 1og5B-3sllA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACL_C_REAC503_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3sll PROBABLE ENOYL-COA
HYDRATASE/ISOMERASE
(Mycobacteroides
abscessus) 		5 / 10 ILE A 109
ALA A 133
GLN A 131
ALA A 176
ILE A 106
 None
 1.09A 2aclC-3sllA:
undetectable		 2aclC-3sllA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEY_A_EV1A1771_1
(CAMP AND
CAMP-INHIBITED CGMP
3', 5'-CYCLIC
PHOSPHODIESTERASE)		 3sll PROBABLE ENOYL-COA
HYDRATASE/ISOMERASE
(Mycobacteroides
abscessus) 		5 / 12 LEU A 120
LEU A  18
VAL A   4
MET A 101
PHE A  35
 None
 1.18A 2weyA-3sllA:
undetectable		 2weyA-3sllA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TIC_A_ZMRA1002_2
(NEURAMINIDASE)		 3sll PROBABLE ENOYL-COA
HYDRATASE/ISOMERASE
(Mycobacteroides
abscessus) 		4 / 5 LEU A 122
ARG A 127
ILE A 182
ARG A 163
 GOL  A 270 (-4.6A)
GOL  A 270 (-3.0A)
None
None
 1.37A 3ticA-3sllA:
undetectable		 3ticA-3sllA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V81_A_NVPA901_1
(HIV-1 REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 3sll PROBABLE ENOYL-COA
HYDRATASE/ISOMERASE
(Mycobacteroides
abscessus) 		4 / 8 LEU A 195
VAL A 128
LEU A  15
TYR A 199
 None
 0.96A 3v81A-3sllA:
undetectable		 3v81A-3sllA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V81_C_NVPC901_1
(HIV-1 REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 3sll PROBABLE ENOYL-COA
HYDRATASE/ISOMERASE
(Mycobacteroides
abscessus) 		4 / 8 LEU A 195
VAL A 128
LEU A  15
TYR A 199
 None
 0.98A 3v81C-3sllA:
undetectable		 3v81C-3sllA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DU2_A_LDPA501_1
(CYTOCHROME P450 BM3
VARIANT B7)		 3sll PROBABLE ENOYL-COA
HYDRATASE/ISOMERASE
(Mycobacteroides
abscessus) 		4 / 7 ALA A 129
PHE A 135
ALA A 113
ALA A 107
 None
 0.95A 4du2A-3sllA:
undetectable		 4du2A-3sllA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DU2_B_LDPB501_1
(CYTOCHROME P450 BM3
VARIANT B7)		 3sll PROBABLE ENOYL-COA
HYDRATASE/ISOMERASE
(Mycobacteroides
abscessus) 		4 / 7 ALA A 129
PHE A 135
ALA A 113
ALA A 107
 None
 0.87A 4du2B-3sllA:
undetectable		 4du2B-3sllA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_C_CLQC303_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3sll PROBABLE ENOYL-COA
HYDRATASE/ISOMERASE
(Mycobacteroides
abscessus) 		4 / 5 GLY A 111
GLY A  59
MET A  24
ASN A  25
 None
 1.23A 4fglC-3sllA:
undetectable		 4fglC-3sllA:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWD_C_NVPC901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 3sll PROBABLE ENOYL-COA
HYDRATASE/ISOMERASE
(Mycobacteroides
abscessus) 		4 / 8 LEU A 195
VAL A 128
LEU A  15
TYR A 199
 None
 0.91A 4pwdC-3sllA:
undetectable		 4pwdC-3sllA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WYQ_B_SAMB301_0
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 3sll PROBABLE ENOYL-COA
HYDRATASE/ISOMERASE
(Mycobacteroides
abscessus) 		5 / 12 GLY A 115
ILE A  95
LEU A 120
GLY A 117
GLY A 116
 None
 1.00A 5wyqB-3sllA:
undetectable		 5wyqB-3sllA:
24.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_A_AQ4A602_0
(CYTOCHROME P450 1A1)		 3sll PROBABLE ENOYL-COA
HYDRATASE/ISOMERASE
(Mycobacteroides
abscessus) 		5 / 12 SER A 191
ASN A  25
ASN A  19
ASP A 132
GLY A 111
 None
 1.27A 6dwnA-3sllA:
undetectable		 6dwnA-3sllA:
15.90