SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3slr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7W_A_MTXA301_1
(PTERIDINE REDUCTASE)		 3slr UNCHARACTERIZED
PROTEIN BF1531
(Bacteroides
fragilis) 		5 / 12 PRO A 357
LEU A 367
LEU A 225
LEU A 227
ASP A 228
 None
None
None
None
MG  A 388 ( 2.7A)
 1.41A 1e7wA-3slrA:
7.6		 1e7wA-3slrA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PKV_B_RBFB101_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 3slr UNCHARACTERIZED
PROTEIN BF1531
(Bacteroides
fragilis) 		5 / 11 ILE A  51
LEU A  36
THR A  33
THR A 210
ILE A 211
 None
 1.28A 1pkvA-3slrA:
undetectable
1pkvB-3slrA:
undetectable		 1pkvA-3slrA:
11.11
1pkvB-3slrA:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QO5_A_CHDA131_0
(LIVER-BASIC FATTY
ACID BINDING PROTEIN)		 3slr UNCHARACTERIZED
PROTEIN BF1531
(Bacteroides
fragilis) 		5 / 12 ILE A 226
LEU A 367
THR A 232
PHE A 261
LEU A 298
 None
 1.20A 2qo5A-3slrA:
undetectable		 2qo5A-3slrA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQW_I_ACHI323_0
(ELIC PENTAMERIC
LIGAND GATED ION
CHANNEL FROM ERWINIA
CHRYSANTHEMI)		 3slr UNCHARACTERIZED
PROTEIN BF1531
(Bacteroides
fragilis) 		4 / 8 ILE A  40
TYR A 126
LEU A 173
PHE A  83
 None
 0.72A 3rqwI-3slrA:
undetectable
3rqwJ-3slrA:
undetectable		 3rqwI-3slrA:
21.50
3rqwJ-3slrA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G77_A_TLFA711_0
(LACTOTRANSFERRIN)		 3slr UNCHARACTERIZED
PROTEIN BF1531
(Bacteroides
fragilis) 		4 / 7 ILE A 320
LEU A 324
ALA A 276
VAL A 277
 None
 0.82A 4g77A-3slrA:
undetectable		 4g77A-3slrA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4II8_A_010A210_0
(LYSOZYME C)		 3slr UNCHARACTERIZED
PROTEIN BF1531
(Bacteroides
fragilis) 		4 / 7 GLU A  43
ASP A 212
ASN A 371
ILE A 205
 None
 1.22A 4ii8A-3slrA:
undetectable		 4ii8A-3slrA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J14_A_X2NA602_1
(CHOLESTEROL
24-HYDROXYLASE)		 3slr UNCHARACTERIZED
PROTEIN BF1531
(Bacteroides
fragilis) 		5 / 10 ALA A 202
LEU A 203
ILE A  40
ALA A  37
ALA A  32
 None
 1.01A 4j14A-3slrA:
undetectable		 4j14A-3slrA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QC6_B_KANB201_2
(BIFUNCTIONAL AAC/APH)		 3slr UNCHARACTERIZED
PROTEIN BF1531
(Bacteroides
fragilis) 		3 / 3 LEU A  23
ASP A  78
TYR A  79
 None
 0.55A 4qc6B-3slrA:
undetectable		 4qc6B-3slrA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_B_SAMB301_0
(UNCHARACTERIZED
PROTEIN)		 3slr UNCHARACTERIZED
PROTEIN BF1531
(Bacteroides
fragilis) 		5 / 12 ARG A 108
GLU A 195
ALA A  32
GLY A  29
TYR A  58
 None
 1.22A 4r29B-3slrA:
undetectable		 4r29B-3slrA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RYA_A_MTLA501_1
(ABC TRANSPORTER
SUBSTRATE BINDING
PROTEIN (SORBITOL))		 3slr UNCHARACTERIZED
PROTEIN BF1531
(Bacteroides
fragilis) 		3 / 3 GLU A  91
TYR A 191
GLU A 195
 None
 0.80A 4ryaA-3slrA:
2.4		 4ryaA-3slrA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WW7_A_ACTA305_0
(EKC/KEOPS COMPLEX
SUBUNIT BUD32)		 3slr UNCHARACTERIZED
PROTEIN BF1531
(Bacteroides
fragilis) 		4 / 6 LEU A 114
LEU A 115
ILE A  65
MET A  66
 None
 0.73A 4ww7A-3slrA:
undetectable		 4ww7A-3slrA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUE_A_SAMA303_1
(CATECHOL
O-METHYLTRANSFERASE)		 3slr UNCHARACTERIZED
PROTEIN BF1531
(Bacteroides
fragilis) 		4 / 5 GLY A 137
TYR A 149
SER A 146
GLU A 132
 None
 1.36A 4xueA-3slrA:
4.3		 4xueA-3slrA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I73_A_68PA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 3slr UNCHARACTERIZED
PROTEIN BF1531
(Bacteroides
fragilis) 		5 / 12 ILE A 226
ALA A 276
GLY A 350
LEU A 324
VAL A 344
 None
 0.96A 5i73A-3slrA:
undetectable		 5i73A-3slrA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GTQ_B_ACTB207_0
(DUF1778
DOMAIN-CONTAINING
PROTEIN
N-ACETYLTRANSFERASE)		 3slr UNCHARACTERIZED
PROTEIN BF1531
(Bacteroides
fragilis) 		4 / 6 LEU A 173
CYH A 171
GLY A 175
ARG A 209
 None
 1.31A 6gtqB-3slrA:
undetectable
6gtqD-3slrA:
undetectable		 6gtqB-3slrA:
19.11
6gtqD-3slrA:
11.15