SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3sn0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_A_AICA5001_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)		 3sn0 PUTATIVE
L-ALANINE-DL-GLUTAMA
TE EPIMERASE
(Paraburkholderia
xenovorans) 		4 / 8 TYR A 227
GLU A 243
HIS A 123
SER A 122
 None
MG  A 408 (-3.2A)
FUM  A 500 (-4.0A)
None
 1.27A 1nx9A-3sn0A:
undetectable		 1nx9A-3sn0A:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_B_AICB5002_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)		 3sn0 PUTATIVE
L-ALANINE-DL-GLUTAMA
TE EPIMERASE
(Paraburkholderia
xenovorans) 		4 / 8 TYR A 227
GLU A 243
HIS A 123
SER A 122
 None
MG  A 408 (-3.2A)
FUM  A 500 (-4.0A)
None
 1.27A 1nx9B-3sn0A:
undetectable		 1nx9B-3sn0A:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_C_AICC5003_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)		 3sn0 PUTATIVE
L-ALANINE-DL-GLUTAMA
TE EPIMERASE
(Paraburkholderia
xenovorans) 		4 / 8 TYR A 227
GLU A 243
HIS A 123
SER A 122
 None
MG  A 408 (-3.2A)
FUM  A 500 (-4.0A)
None
 1.28A 1nx9C-3sn0A:
undetectable		 1nx9C-3sn0A:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_D_AICD5004_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)		 3sn0 PUTATIVE
L-ALANINE-DL-GLUTAMA
TE EPIMERASE
(Paraburkholderia
xenovorans) 		4 / 8 TYR A 227
GLU A 243
HIS A 123
SER A 122
 None
MG  A 408 (-3.2A)
FUM  A 500 (-4.0A)
None
 1.28A 1nx9D-3sn0A:
undetectable		 1nx9D-3sn0A:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B7Z_B_MK1B200_2
(HIV-1 PROTEASE)		 3sn0 PUTATIVE
L-ALANINE-DL-GLUTAMA
TE EPIMERASE
(Paraburkholderia
xenovorans) 		5 / 12 ARG A 273
GLY A  80
ASP A 290
GLY A  87
ILE A  86
 None
 0.83A 2b7zB-3sn0A:
undetectable		 2b7zB-3sn0A:
12.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DQY_C_CHDC3_0
(LIVER
CARBOXYLESTERASE 1)		 3sn0 PUTATIVE
L-ALANINE-DL-GLUTAMA
TE EPIMERASE
(Paraburkholderia
xenovorans) 		4 / 6 LEU A 216
LEU A 201
PRO A 125
VAL A 145
 None
 1.15A 2dqyC-3sn0A:
2.2		 2dqyC-3sn0A:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E7F_A_C2FA3000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 3sn0 PUTATIVE
L-ALANINE-DL-GLUTAMA
TE EPIMERASE
(Paraburkholderia
xenovorans) 		5 / 12 GLU A  34
PHE A 354
ASN A 317
ARG A 346
ILE A 292
 None
 1.28A 2e7fA-3sn0A:
11.0		 2e7fA-3sn0A:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NMZ_B_ROCB401_3
(PROTEASE)		 3sn0 PUTATIVE
L-ALANINE-DL-GLUTAMA
TE EPIMERASE
(Paraburkholderia
xenovorans) 		6 / 12 ARG A 273
GLY A  80
ASP A 290
ILE A 292
GLY A  87
ILE A  86
 None
 1.43A 2nmzB-3sn0A:
undetectable		 2nmzB-3sn0A:
12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZBU_D_ADND504_1
(UNCHARACTERIZED
CONSERVED PROTEIN)		 3sn0 PUTATIVE
L-ALANINE-DL-GLUTAMA
TE EPIMERASE
(Paraburkholderia
xenovorans) 		3 / 3 PHE A 270
ASN A 294
PHE A 275
 None
 1.05A 2zbuD-3sn0A:
undetectable		 2zbuD-3sn0A:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_E_TRPE1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3sn0 PUTATIVE
L-ALANINE-DL-GLUTAMA
TE EPIMERASE
(Paraburkholderia
xenovorans) 		4 / 7 GLY A 226
VAL A 189
ILE A 244
VAL A 255
 None
 0.79A 3fi0E-3sn0A:
undetectable		 3fi0E-3sn0A:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_G_TRPG1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3sn0 PUTATIVE
L-ALANINE-DL-GLUTAMA
TE EPIMERASE
(Paraburkholderia
xenovorans) 		4 / 8 GLY A 226
VAL A 189
ILE A 244
VAL A 255
 None
 0.77A 3fi0G-3sn0A:
undetectable		 3fi0G-3sn0A:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_Q_TRPQ1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3sn0 PUTATIVE
L-ALANINE-DL-GLUTAMA
TE EPIMERASE
(Paraburkholderia
xenovorans) 		4 / 8 GLY A 226
VAL A 189
ILE A 244
VAL A 255
 None
 0.75A 3fi0Q-3sn0A:
undetectable		 3fi0Q-3sn0A:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KK6_A_CELA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3sn0 PUTATIVE
L-ALANINE-DL-GLUTAMA
TE EPIMERASE
(Paraburkholderia
xenovorans) 		5 / 12 VAL A  47
LEU A  51
PHE A  66
GLY A  87
ALA A  88
 None
 1.04A 3kk6A-3sn0A:
undetectable		 3kk6A-3sn0A:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NY4_A_SMXA309_1
(BETA-LACTAMASE)		 3sn0 PUTATIVE
L-ALANINE-DL-GLUTAMA
TE EPIMERASE
(Paraburkholderia
xenovorans) 		4 / 5 ILE A 292
ARG A 346
THR A 324
GLU A 350
 None
 1.25A 3ny4A-3sn0A:
undetectable		 3ny4A-3sn0A:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PFG_A_SAMA264_0
(N-METHYLTRANSFERASE)		 3sn0 PUTATIVE
L-ALANINE-DL-GLUTAMA
TE EPIMERASE
(Paraburkholderia
xenovorans) 		5 / 12 ALA A  92
GLY A  31
LEU A  94
PHE A  20
SER A  33
 None
 1.32A 3pfgA-3sn0A:
undetectable		 3pfgA-3sn0A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R0L_D_ACTD127_0
(PHOSPHOLIPASE A2 CB)		 3sn0 PUTATIVE
L-ALANINE-DL-GLUTAMA
TE EPIMERASE
(Paraburkholderia
xenovorans) 		4 / 5 PHE A  35
ILE A  48
GLY A  43
HIS A  19
 None
 1.25A 3r0lD-3sn0A:
undetectable		 3r0lD-3sn0A:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYE_B_YTZB902_1
(DIHYDROPTEROATE
SYNTHASE)		 3sn0 PUTATIVE
L-ALANINE-DL-GLUTAMA
TE EPIMERASE
(Paraburkholderia
xenovorans) 		3 / 3 PHE A  67
LYS A 301
SER A 299
 None
 1.11A 3tyeB-3sn0A:
10.2		 3tyeB-3sn0A:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DUB_B_LDPB501_1
(CYTOCHROME P450 BM3
VARIANT 9D7)		 3sn0 PUTATIVE
L-ALANINE-DL-GLUTAMA
TE EPIMERASE
(Paraburkholderia
xenovorans) 		4 / 6 PHE A  66
ALA A  70
GLY A  85
VAL A  47
 None
 0.95A 4dubB-3sn0A:
undetectable		 4dubB-3sn0A:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3sn0 PUTATIVE
L-ALANINE-DL-GLUTAMA
TE EPIMERASE
(Paraburkholderia
xenovorans) 		4 / 8 ASP A  36
ASP A 290
ASP A 343
ARG A 346
 None
 1.13A 4gkhF-3sn0A:
undetectable		 4gkhF-3sn0A:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JVL_A_ESTA702_1
(ESTROGEN
SULFOTRANSFERASE)		 3sn0 PUTATIVE
L-ALANINE-DL-GLUTAMA
TE EPIMERASE
(Paraburkholderia
xenovorans) 		4 / 9 TYR A 319
LYS A 161
HIS A 123
PHE A  39
 None
FUM  A 500 (-3.3A)
FUM  A 500 (-4.0A)
None
 1.33A 4jvlA-3sn0A:
undetectable		 4jvlA-3sn0A:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M11_A_MXMA606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3sn0 PUTATIVE
L-ALANINE-DL-GLUTAMA
TE EPIMERASE
(Paraburkholderia
xenovorans) 		5 / 12 ILE A 244
VAL A 242
LEU A 239
LEU A 218
SER A 259
 None
 1.07A 4m11A-3sn0A:
undetectable		 4m11A-3sn0A:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YV5_A_SVRA205_2
(BASIC PHOSPHOLIPASE
A2 HOMOLOG 2)		 3sn0 PUTATIVE
L-ALANINE-DL-GLUTAMA
TE EPIMERASE
(Paraburkholderia
xenovorans) 		4 / 6 PHE A 183
LEU A 187
ASN A 221
PRO A 177
 None
 1.41A 4yv5B-3sn0A:
undetectable		 4yv5B-3sn0A:
13.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YV5_B_SVRB207_1
(BASIC PHOSPHOLIPASE
A2 HOMOLOG 2)		 3sn0 PUTATIVE
L-ALANINE-DL-GLUTAMA
TE EPIMERASE
(Paraburkholderia
xenovorans) 		4 / 6 PHE A 183
LEU A 187
ASN A 221
PRO A 177
 None
 1.40A 4yv5A-3sn0A:
undetectable		 4yv5A-3sn0A:
13.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		 3sn0 PUTATIVE
L-ALANINE-DL-GLUTAMA
TE EPIMERASE
(Paraburkholderia
xenovorans) 		4 / 7 LEU A 109
VAL A 334
ASN A  91
ILE A 292
 None
 1.16A 5jh7C-3sn0A:
undetectable		 5jh7C-3sn0A:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JWA_H_ACTH612_0
(NADH DEHYDROGENASE,
PUTATIVE)		 3sn0 PUTATIVE
L-ALANINE-DL-GLUTAMA
TE EPIMERASE
(Paraburkholderia
xenovorans) 		3 / 3 ARG A 370
PRO A 368
ASN A 329
 None
 1.07A 5jwaA-3sn0A:
undetectable
5jwaH-3sn0A:
undetectable		 5jwaA-3sn0A:
19.89
5jwaH-3sn0A:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NU7_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 4)		 3sn0 PUTATIVE
L-ALANINE-DL-GLUTAMA
TE EPIMERASE
(Paraburkholderia
xenovorans) 		4 / 8 LEU A 216
ALA A 203
VAL A 242
HIS A 167
 None
 0.97A 5nu7A-3sn0A:
undetectable		 5nu7A-3sn0A:
17.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODI_D_ACTD202_0
(METHYL-VIOLOGEN
REDUCING
HYDROGENASE, SUBUNIT
D)		 3sn0 PUTATIVE
L-ALANINE-DL-GLUTAMA
TE EPIMERASE
(Paraburkholderia
xenovorans) 		3 / 3 HIS A  63
GLU A  90
TRP A 297
 None
 1.11A 5odiD-3sn0A:
undetectable		 5odiD-3sn0A:
15.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODQ_D_ACTD202_0
(METHYL-VIOLOGEN
REDUCING
HYDROGENASE, SUBUNIT
D)		 3sn0 PUTATIVE
L-ALANINE-DL-GLUTAMA
TE EPIMERASE
(Paraburkholderia
xenovorans) 		3 / 3 HIS A  63
GLU A  90
TRP A 297
 None
 0.98A 5odqD-3sn0A:
undetectable		 5odqD-3sn0A:
15.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODR_D_ACTD202_0
(METHYL-VIOLOGEN
REDUCING
HYDROGENASE, SUBUNIT
D)		 3sn0 PUTATIVE
L-ALANINE-DL-GLUTAMA
TE EPIMERASE
(Paraburkholderia
xenovorans) 		3 / 3 HIS A  63
GLU A  90
TRP A 297
 None
 1.06A 5odrD-3sn0A:
undetectable		 5odrD-3sn0A:
15.54