SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3snh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_J_TRPJ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3snh DYNAMIN-1
(Homo
sapiens) 		4 / 8 GLY A  53
ALA A 251
THR A 274
ILE A 248
 None
 0.76A 1c9sI-3snhA:
undetectable
1c9sJ-3snhA:
undetectable		 1c9sI-3snhA:
6.70
1c9sJ-3snhA:
6.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3snh DYNAMIN-1
(Homo
sapiens) 		4 / 8 GLY A  53
ALA A 251
THR A 274
ILE A 248
 None
 0.73A 1c9sU-3snhA:
undetectable
1c9sV-3snhA:
undetectable		 1c9sU-3snhA:
6.70
1c9sV-3snhA:
6.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_A_TRPA81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3snh DYNAMIN-1
(Homo
sapiens) 		4 / 7 GLY A  53
ALA A 251
THR A 274
ILE A 248
 None
 0.74A 1gtnA-3snhA:
undetectable
1gtnK-3snhA:
undetectable		 1gtnA-3snhA:
6.70
1gtnK-3snhA:
6.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_B_TRPB81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3snh DYNAMIN-1
(Homo
sapiens) 		4 / 8 GLY A  53
ALA A 251
THR A 274
ILE A 248
 None
 0.72A 1gtnA-3snhA:
undetectable
1gtnB-3snhA:
undetectable		 1gtnA-3snhA:
6.70
1gtnB-3snhA:
6.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_F_TRPF81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3snh DYNAMIN-1
(Homo
sapiens) 		4 / 8 GLY A  53
ALA A 251
THR A 274
ILE A 248
 None
 0.77A 1gtnE-3snhA:
undetectable
1gtnF-3snhA:
undetectable		 1gtnE-3snhA:
6.70
1gtnF-3snhA:
6.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3snh DYNAMIN-1
(Homo
sapiens) 		4 / 8 GLY A  53
ALA A 251
THR A 274
ILE A 248
 None
 0.67A 1gtnP-3snhA:
undetectable
1gtnQ-3snhA:
undetectable		 1gtnP-3snhA:
6.70
1gtnQ-3snhA:
6.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQW_A_RTLA135_0
(CELLULAR
RETINOL-BINDING
PROTEIN)		 3snh DYNAMIN-1
(Homo
sapiens) 		5 / 12 ILE A 742
GLN A  17
LEU A 296
LEU A 285
ILE A 289
 None
 1.29A 1kqwA-3snhA:
undetectable		 1kqwA-3snhA:
10.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_F_TRPF81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3snh DYNAMIN-1
(Homo
sapiens) 		4 / 8 GLY A  53
ALA A 251
THR A 274
ILE A 248
 None
 0.76A 1utdF-3snhA:
undetectable
1utdG-3snhA:
undetectable		 1utdF-3snhA:
6.70
1utdG-3snhA:
6.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_I_TRPI81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3snh DYNAMIN-1
(Homo
sapiens) 		4 / 8 GLY A  53
ALA A 251
THR A 274
ILE A 248
 None
 0.75A 1utdI-3snhA:
undetectable
1utdJ-3snhA:
undetectable		 1utdI-3snhA:
6.70
1utdJ-3snhA:
6.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_J_TRPJ81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3snh DYNAMIN-1
(Homo
sapiens) 		4 / 8 GLY A  53
ALA A 251
THR A 274
ILE A 248
 None
 0.78A 1utdJ-3snhA:
undetectable
1utdK-3snhA:
undetectable		 1utdJ-3snhA:
6.70
1utdK-3snhA:
6.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_B_BEZB12_0
(CES1 PROTEIN)		 3snh DYNAMIN-1
(Homo
sapiens) 		4 / 4 GLY A 202
SER A 175
VAL A 219
LEU A 227
 None
 0.96A 1yajB-3snhA:
undetectable		 1yajB-3snhA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BXO_A_SAMA238_1
(N,N-DIMETHYLTRANSFER
ASE)		 3snh DYNAMIN-1
(Homo
sapiens) 		3 / 3 TYR A 600
GLU A 562
ASP A 555
 None
 0.81A 3bxoA-3snhA:
undetectable		 3bxoA-3snhA:
15.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BXO_B_SAMB238_1
(N,N-DIMETHYLTRANSFER
ASE)		 3snh DYNAMIN-1
(Homo
sapiens) 		3 / 3 TYR A 600
GLU A 562
ASP A 555
 None
 0.76A 3bxoB-3snhA:
undetectable		 3bxoB-3snhA:
15.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GP0_A_NILA1_2
(MITOGEN-ACTIVATED
PROTEIN KINASE 11)		 3snh DYNAMIN-1
(Homo
sapiens) 		4 / 7 ARG A 237
VAL A 203
LEU A 209
ILE A 232
 None
 0.93A 3gp0A-3snhA:
undetectable		 3gp0A-3snhA:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K2H_B_LYAB514_2
(DIHYDROFOLATE
REDUCTASE/THYMIDYLAT
E SYNTHASE)		 3snh DYNAMIN-1
(Homo
sapiens) 		3 / 3 ARG A  59
THR A 141
THR A 105
 None
 0.81A 3k2hB-3snhA:
undetectable		 3k2hB-3snhA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MTE_A_SAMA220_0
(16S RRNA METHYLASE)		 3snh DYNAMIN-1
(Homo
sapiens) 		5 / 12 GLY A 233
GLY A 273
ALA A 177
LEU A 268
LEU A 207
 None
 1.08A 3mteA-3snhA:
undetectable		 3mteA-3snhA:
14.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OKX_B_SAMB201_0
(YAEB-LIKE PROTEIN
RPA0152)		 3snh DYNAMIN-1
(Homo
sapiens) 		3 / 3 LYS A 376
ARG A 369
LYS A 472
 None
 1.31A 3okxA-3snhA:
undetectable		 3okxA-3snhA:
14.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_B_SAMB6735_0
(16S RRNA METHYLASE)		 3snh DYNAMIN-1
(Homo
sapiens) 		5 / 12 GLY A 233
GLY A 273
ALA A 177
LEU A 268
LEU A 207
 None
 1.08A 3p2kB-3snhA:
undetectable		 3p2kB-3snhA:
14.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVQ_A_ACTA904_0
(TYROSINE-PROTEIN
KINASE JAK2)		 3snh DYNAMIN-1
(Homo
sapiens) 		3 / 3 PHE A 317
VAL A 311
GLU A 308
 None
 0.59A 4fvqA-3snhA:
undetectable		 4fvqA-3snhA:
17.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GH8_B_MTXB201_1
(DIHYDROFOLATE
REDUCTASE)		 3snh DYNAMIN-1
(Homo
sapiens) 		5 / 12 ILE A 388
ALA A 408
LEU A 665
ASN A 498
ARG A 663
 None
 1.31A 4gh8B-3snhA:
undetectable		 4gh8B-3snhA:
13.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L9Q_B_9TPB601_1
(SERUM ALBUMIN)		 3snh DYNAMIN-1
(Homo
sapiens) 		5 / 12 PRO A 627
ALA A 618
ILE A 585
LEU A 588
LEU A 603
 None
 1.18A 4l9qB-3snhA:
1.7		 4l9qB-3snhA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_C_STRC601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3snh DYNAMIN-1
(Homo
sapiens) 		4 / 5 ILE A 412
ASP A 380
GLU A 387
VAL A 659
 None
 1.16A 4nkxC-3snhA:
2.9		 4nkxC-3snhA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVJ_B_478B101_2
(HIV-1 PROTEASE)		 3snh DYNAMIN-1
(Homo
sapiens) 		6 / 9 LEU A 170
GLY A 202
ALA A 173
VAL A 164
GLY A  38
ILE A 171
 None
 1.49A 4rvjB-3snhA:
undetectable		 4rvjB-3snhA:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_A_ADNA2414_1
(RNA-DIRECTED RNA
POLYMERASE L)		 3snh DYNAMIN-1
(Homo
sapiens) 		4 / 6 GLU A 491
PHE A 493
TYR A 669
HIS A 490
 None
 1.45A 4uciA-3snhA:
undetectable		 4uciA-3snhA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_B_ADNB2415_1
(RNA-DIRECTED RNA
POLYMERASE L)		 3snh DYNAMIN-1
(Homo
sapiens) 		4 / 7 GLU A 491
PHE A 493
TYR A 669
HIS A 490
 None
 1.49A 4uciB-3snhA:
undetectable		 4uciB-3snhA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GWK_F_EVPF102_1
(DNA TOPOISOMERASE
2-ALPHA)		 3snh DYNAMIN-1
(Homo
sapiens) 		4 / 5 GLY A 743
ASP A 744
ARG A 297
MET A 731
 None
 1.22A 5gwkA-3snhA:
4.0		 5gwkA-3snhA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ONL_A_010A302_0
(YNDL)		 3snh DYNAMIN-1
(Homo
sapiens) 		4 / 5 GLU A 387
LYS A 415
GLU A 383
PHE A 379
 None
 1.12A 5onlA-3snhA:
1.9		 5onlA-3snhA:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B0L_B_TA1B502_1
(TUBULIN BETA CHAIN)		 3snh DYNAMIN-1
(Homo
sapiens) 		5 / 12 VAL A  70
LEU A 296
LEU A  16
THR A 292
LEU A 285
 None
 1.06A 6b0lB-3snhA:
undetectable		 6b0lB-3snhA:
8.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_G_EU7G101_0
(MATRIX PROTEIN 2)		 3snh DYNAMIN-1
(Homo
sapiens) 		5 / 9 ALA A  42
SER A  41
ALA A 186
GLY A  38
SER A 184
 None
 1.22A 6bklE-3snhA:
undetectable
6bklF-3snhA:
undetectable
6bklG-3snhA:
undetectable
6bklH-3snhA:
undetectable		 6bklE-3snhA:
2.99
6bklF-3snhA:
2.99
6bklG-3snhA:
2.99
6bklH-3snhA:
2.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_G_EU7G101_0
(MATRIX PROTEIN 2)		 3snh DYNAMIN-1
(Homo
sapiens) 		5 / 9 ALA A  42
SER A  41
ALA A 186
GLY A  38
SER A 184
 None
 1.22A 6bklE-3snhA:
undetectable
6bklF-3snhA:
undetectable
6bklG-3snhA:
undetectable
6bklH-3snhA:
undetectable		 6bklE-3snhA:
2.99
6bklF-3snhA:
2.99
6bklG-3snhA:
2.99
6bklH-3snhA:
2.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HRJ_A_010A302_0
(YNDL)		 3snh DYNAMIN-1
(Homo
sapiens) 		4 / 5 GLU A 387
LYS A 415
GLU A 383
PHE A 379
 None
 1.13A 6hrjA-3snhA:
2.2		 6hrjA-3snhA:
15.28