SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3sns'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_B_803B311_1
(ANTIGEN CD11A (P180))		 3sns LIPOPROTEIN 34
(Escherichia
coli) 		4 / 7 VAL A 337
LEU A 259
TYR A 280
LEU A 326
 None
 0.86A 1cqpA-3snsA:
undetectable
1cqpB-3snsA:
undetectable		 1cqpA-3snsA:
17.78
1cqpB-3snsA:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XMU_A_ROFA101_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4B)		 3sns LIPOPROTEIN 34
(Escherichia
coli) 		4 / 5 MET A 264
ASN A 331
THR A 327
GLN A 330
 None
 1.40A 1xmuA-3snsA:
undetectable		 1xmuA-3snsA:
16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_C_SVRC507_2
(PHOSPHOLIPASE A2)		 3sns LIPOPROTEIN 34
(Escherichia
coli) 		4 / 6 VAL A 244
VAL A 243
GLN A 317
ARG A 313
 None
 1.09A 3bjwF-3snsA:
undetectable		 3bjwF-3snsA:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B3Q_A_NVPA999_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 3sns LIPOPROTEIN 34
(Escherichia
coli) 		4 / 7 LEU A 334
TYR A 280
TYR A 303
LEU A 326
 None
 1.12A 4b3qA-3snsA:
2.6		 4b3qA-3snsA:
11.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_A_SAMA602_1
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 3sns LIPOPROTEIN 34
(Escherichia
coli) 		3 / 3 ASP A 229
ASN A 312
SER A 232
 None
 0.87A 4obwA-3snsA:
undetectable		 4obwA-3snsA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ALC_L_TIQL1210_2
(ANTI-TICAGRELOR FAB
72, LIGHT CHAIN)		 3sns LIPOPROTEIN 34
(Escherichia
coli) 		4 / 8 SER A 314
GLY A 308
SER A 269
GLY A 274
 None
None
CL  A   3 ( 4.5A)
None
 0.79A 5alcL-3snsA:
undetectable		 5alcL-3snsA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KVA_A_SAMA301_1
(CAFFEOYL-COA
O-METHYLTRANSFERASE)		 3sns LIPOPROTEIN 34
(Escherichia
coli) 		3 / 3 THR A 327
SER A 329
ASP A 295
 None
 0.74A 5kvaA-3snsA:
undetectable		 5kvaA-3snsA:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KVA_B_SAMB301_1
(CAFFEOYL-COA
O-METHYLTRANSFERASE)		 3sns LIPOPROTEIN 34
(Escherichia
coli) 		3 / 3 THR A 327
SER A 329
ASP A 295
 None
 0.75A 5kvaB-3snsA:
undetectable		 5kvaB-3snsA:
15.71