SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3so6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KI3_A_PE2A1_1
(THYMIDINE KINASE)		 3so6 LDL RECEPTOR ADAPTOR
PROTEIN
(Rattus
norvegicus) 		5 / 12 HIS A 143
ILE A 107
GLN A  85
TYR A  51
GLU A 108
 None
 1.20A 1ki3A-3so6A:
undetectable		 1ki3A-3so6A:
16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1479_0
(MJ0495-LIKE PROTEIN)		 3so6 LDL RECEPTOR ADAPTOR
PROTEIN
(Rattus
norvegicus) 		4 / 5 THR A  99
ILE A 107
GLU A 108
PHE A 145
 None
 1.15A 4ac9C-3so6A:
undetectable		 4ac9C-3so6A:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1479_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 3so6 LDL RECEPTOR ADAPTOR
PROTEIN
(Rattus
norvegicus) 		4 / 5 THR A  99
ILE A 107
GLU A 108
PHE A 145
 None
 1.12A 4acaC-3so6A:
undetectable		 4acaC-3so6A:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1479_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 3so6 LDL RECEPTOR ADAPTOR
PROTEIN
(Rattus
norvegicus) 		4 / 5 THR A  99
ILE A 107
GLU A 108
PHE A 145
 None
 1.17A 4acbC-3so6A:
undetectable		 4acbC-3so6A:
15.38