SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3sob'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BDW_B_DVAB6_0
(GRAMICIDIN A)		 3sob LOW-DENSITY
LIPOPROTEIN
RECEPTOR-RELATED
PROTEIN 6
(Homo
sapiens) 		3 / 3 TRP B  67
ALA B  54
VAL B  56
 None
 0.91A 1bdwA-3sobB:
undetectable
1bdwB-3sobB:
undetectable		 1bdwA-3sobB:
4.15
1bdwB-3sobB:
4.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JGL_L_ESTL911_1
(IG GAMMA-1-CHAIN
IG KAPPA-CHAIN)		 3sob LOW-DENSITY
LIPOPROTEIN
RECEPTOR-RELATED
PROTEIN 6
(Homo
sapiens) 		5 / 10 GLN B 279
GLY B 106
ALA B 101
LEU B 145
TYR B 110
 None
 1.20A 1jglH-3sobB:
undetectable
1jglL-3sobB:
undetectable		 1jglH-3sobB:
20.57
1jglL-3sobB:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GP0_A_NILA1_2
(MITOGEN-ACTIVATED
PROTEIN KINASE 11)		 3sob LOW-DENSITY
LIPOPROTEIN
RECEPTOR-RELATED
PROTEIN 6
(Homo
sapiens) 		4 / 7 ARG B  77
LEU B  24
LEU B 232
ILE B 143
 None
 0.92A 3gp0A-3sobB:
undetectable		 3gp0A-3sobB:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWU_A_ACAA18_2
(WTFP-TAG,GP41)		 3sob LOW-DENSITY
LIPOPROTEIN
RECEPTOR-RELATED
PROTEIN 6
(Homo
sapiens) 		3 / 3 LEU B 187
LEU B 230
TRP B 239
 None
 0.75A 5nwuA-3sobB:
undetectable		 5nwuA-3sobB:
12.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UIH_A_8CVA201_1
(DIHYDROFOLATE
REDUCTASE)		 3sob LOW-DENSITY
LIPOPROTEIN
RECEPTOR-RELATED
PROTEIN 6
(Homo
sapiens) 		4 / 8 ALA B 101
MET B 152
LEU B 187
ILE B 119
 None
 0.90A 5uihA-3sobB:
undetectable		 5uihA-3sobB:
12.58