SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3sog'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S14_B_NOVB2300_1
(TOPOISOMERASE IV
SUBUNIT B)		 3sog AMPHIPHYSIN
(Homo
sapiens) 		5 / 12 ASP A 108
GLU A 107
ASP A 103
ALA A  65
ILE A  67
 None
K  A 238 ( 4.9A)
K  A 238 ( 3.6A)
None
None
 1.22A 1s14B-3sogA:
undetectable		 1s14B-3sogA:
24.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3F33_A_PFLA2001_1
(FERRITIN LIGHT CHAIN)		 3sog AMPHIPHYSIN
(Homo
sapiens) 		4 / 6 LEU A 113
SER A 117
LEU A 121
LEU A  64
 None
 0.94A 3f33A-3sogA:
4.4		 3f33A-3sogA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MZE_A_CFXA364_2
(D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
DACA)		 3sog AMPHIPHYSIN
(Homo
sapiens) 		3 / 3 SER A 210
SER A 211
HIS A 217
 None
 0.66A 3mzeA-3sogA:
undetectable		 3mzeA-3sogA:
19.83