SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3soj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_C_SAMC2293_0
(GLYCINE
N-METHYLTRANSFERASE)		 3soj PILE
(Francisella
tularensis) 		5 / 12 TYR A  62
ALA A  45
SER A  46
TRP A 112
GLY A  76
 None
 1.27A 1nbiC-3sojA:
undetectable		 1nbiC-3sojA:
16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_D_SAMD3293_0
(GLYCINE
N-METHYLTRANSFERASE)		 3soj PILE
(Francisella
tularensis) 		5 / 12 TYR A  62
ALA A  45
SER A  46
TRP A 112
GLY A  76
 None
 1.28A 1nbiD-3sojA:
undetectable		 1nbiD-3sojA:
16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNH_B_9CRB502_1
(CYTOCHROME P450 2C8)		 3soj PILE
(Francisella
tularensis) 		5 / 10 SER A  36
ILE A  33
LEU A 123
ASN A 117
ILE A  97
 None
 1.17A 2nnhB-3sojA:
undetectable		 2nnhB-3sojA:
12.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KSZ_A_CYSA620_0
(LACTOPEROXIDASE)		 3soj PILE
(Francisella
tularensis) 		3 / 3 ARG A  30
GLU A  29
PHE A  91
 None
 0.88A 4kszA-3sojA:
undetectable		 4kszA-3sojA:
10.09