SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3sok'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IYF_A_ERYA1400_0
(OLEANDOMYCIN
GLYCOSYLTRANSFERASE)		 3sok FIMBRIAL PROTEIN
(Dichelobacter
nodosus) 		5 / 11 ASN A 134
VAL A 122
ILE A  47
ASN A  95
ALA A  40
 None
 1.46A 2iyfA-3sokA:
undetectable		 2iyfA-3sokA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IYF_B_ERYB1399_0
(OLEANDOMYCIN
GLYCOSYLTRANSFERASE)		 3sok FIMBRIAL PROTEIN
(Dichelobacter
nodosus) 		5 / 12 ASN A 134
VAL A 122
ILE A  47
ASN A  95
ALA A  40
 None
 1.45A 2iyfB-3sokA:
undetectable		 2iyfB-3sokA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_F_SC2F1291_1
(FICOLIN-2)		 3sok FIMBRIAL PROTEIN
(Dichelobacter
nodosus) 		4 / 6 SER A  64
SER A  66
ASP A  49
GLU A  52
 None
 1.12A 2j2pE-3sokA:
undetectable
2j2pF-3sokA:
undetectable		 2j2pE-3sokA:
22.37
2j2pF-3sokA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GGU_B_017B201_1
(PROTEASE)		 3sok FIMBRIAL PROTEIN
(Dichelobacter
nodosus) 		5 / 12 ASP A  81
GLY A  82
ASP A 124
VAL A 122
VAL A 100
 None
 1.17A 3gguA-3sokA:
undetectable		 3gguA-3sokA:
24.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N62_A_MTLA870_0
(NITRIC OXIDE
SYNTHASE)		 3sok FIMBRIAL PROTEIN
(Dichelobacter
nodosus) 		4 / 8 SER A 130
ASN A 151
ASN A 128
ASP A  92
 None
 1.29A 3n62A-3sokA:
undetectable		 3n62A-3sokA:
14.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_B_MTLB806_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3sok FIMBRIAL PROTEIN
(Dichelobacter
nodosus) 		4 / 7 SER A 130
ASN A 151
ASN A 128
ASP A  92
 None
 1.35A 4kcnB-3sokA:
undetectable		 4kcnB-3sokA:
14.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M83_A_ERYA1400_0
(OLEANDOMYCIN
GLYCOSYLTRANSFERASE)		 3sok FIMBRIAL PROTEIN
(Dichelobacter
nodosus) 		5 / 11 ASN A 134
VAL A 122
ILE A  47
ASN A  95
ALA A  40
 None
 1.46A 4m83A-3sokA:
undetectable		 4m83A-3sokA:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MFX_A_ACTA701_0
(GENOME POLYPROTEIN)		 3sok FIMBRIAL PROTEIN
(Dichelobacter
nodosus) 		4 / 5 ARG A  46
THR A  79
ALA A  78
ASP A  70
 None
 1.17A 5mfxA-3sokA:
undetectable		 5mfxA-3sokA:
15.60