SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3sol'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2HC4_A_VDXA525_2 (VITAMIN D RECEPTOR)	3sol	TYPE II SECRETION PATHWAY RELATED PROTEIN (Escherichia coli)	4 / 7	LEU A 105 LEU A 104 ARG A 30 SER A 27	None	1.22A	2hc4A-3solA: undetectable	2hc4A-3solA: 17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4TWD_C_377C401_1 (CYS-LOOP LIGAND-GATED ION CHANNEL)	3sol	TYPE II SECRETION PATHWAY RELATED PROTEIN (Escherichia coli)	4 / 6	ASN A 37 GLU A 86 TYR A 31 LEU A 32	CL A 200 (-4.3A) None None None	1.12A	4twdB-3solA: undetectable 4twdC-3solA: undetectable	4twdB-3solA: 14.29 4twdC-3solA: 14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4TWD_E_377E401_1 (CYS-LOOP LIGAND-GATED ION CHANNEL)	3sol	TYPE II SECRETION PATHWAY RELATED PROTEIN (Escherichia coli)	4 / 6	ASN A 37 GLU A 86 TYR A 31 LEU A 32	CL A 200 (-4.3A) None None None	1.11A	4twdD-3solA: undetectable 4twdE-3solA: undetectable	4twdD-3solA: 14.29 4twdE-3solA: 14.29

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2HC4_A_VDXA525_2","VITAMIN D RECEPTOR","3sol","TYPE II SECRETION PATHWAY RELATED PROTEIN","Escherichia coli",4,"LEU A 105;LEU A 104;ARG A  30;SER A  27","None","1.22A","2hc4A-3solA:undetectable","2hc4A-3solA:17.97"],["4TWD_C_377C401_1","CYS-LOOP LIGAND-GATED ION CHANNEL;CYS-LOOP LIGAND-GATED ION CHANNEL","3sol","TYPE II SECRETION PATHWAY RELATED PROTEIN","Escherichia coli",4,"ASN A  37;GLU A  86;TYR A  31;LEU A  32"," CL A 200 (-4.3A);None;None;None","1.12A","4twdB-3solA:undetectable;4twdC-3solA:undetectable","4twdB-3solA:14.29;4twdC-3solA:14.29"],["4TWD_E_377E401_1","CYS-LOOP LIGAND-GATED ION CHANNEL;CYS-LOOP LIGAND-GATED ION CHANNEL","3sol","TYPE II SECRETION PATHWAY RELATED PROTEIN","Escherichia coli",4,"ASN A  37;GLU A  86;TYR A  31;LEU A  32"," CL A 200 (-4.3A);None;None;None","1.11A","4twdD-3solA:undetectable;4twdE-3solA:undetectable","4twdD-3solA:14.29;4twdE-3solA:14.29"]]