SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3son'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_B_HLTB4003_1
(SERUM ALBUMIN)		 3son HYPOTHETICAL NUDIX
HYDROLASE
(Listeria
monocytogenes) 		4 / 6 VAL A  23
GLY A  22
ALA A 120
LEU A 124
 None
 0.70A 1e7bB-3sonA:
undetectable		 1e7bB-3sonA:
13.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDW_A_ESTA350_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE)		 3son HYPOTHETICAL NUDIX
HYDROLASE
(Listeria
monocytogenes) 		5 / 10 VAL A 103
LEU A 105
PRO A  11
VAL A  35
GLU A  55
 None
 1.46A 1fdwA-3sonA:
undetectable		 1fdwA-3sonA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT3_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 3son HYPOTHETICAL NUDIX
HYDROLASE
(Listeria
monocytogenes) 		4 / 7 LEU A 133
LEU A  68
MET A 145
LEU A 140
 None
 1.11A 1kt3A-3sonA:
undetectable		 1kt3A-3sonA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PRG_B_BRLB2_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 3son HYPOTHETICAL NUDIX
HYDROLASE
(Listeria
monocytogenes) 		5 / 12 PHE A  34
LEU A  96
VAL A 103
LEU A 133
LEU A  68
 None
 1.28A 2prgB-3sonA:
undetectable		 2prgB-3sonA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XCT_H_CPFH1020_1
(DNA GYRASE SUBUNIT
B, DNA GYRASE
SUBUNIT A)		 3son HYPOTHETICAL NUDIX
HYDROLASE
(Listeria
monocytogenes) 		3 / 3 ARG A 139
GLU A 135
SER A  53
 None
 0.77A 2xctD-3sonA:
undetectable		 2xctD-3sonA:
13.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FBX_A_ACTA608_0
(PUTATIVE
PHOSPHOLIPASE B-LIKE
2)		 3son HYPOTHETICAL NUDIX
HYDROLASE
(Listeria
monocytogenes) 		3 / 3 GLU A  89
VAL A   7
CYH A  91
 None
 0.99A 3fbxA-3sonA:
undetectable		 3fbxA-3sonA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U5K_A_08JA1_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 3son HYPOTHETICAL NUDIX
HYDROLASE
(Listeria
monocytogenes) 		4 / 8 VAL A 103
LEU A 112
ILE A  94
MET A  65
 None
 0.89A 3u5kA-3sonA:
undetectable		 3u5kA-3sonA:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V5V_A_ACTA511_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 3son HYPOTHETICAL NUDIX
HYDROLASE
(Listeria
monocytogenes) 		4 / 4 ASN A  76
PHE A  79
SER A  80
GLN A   6
 None
 1.48A 3v5vA-3sonA:
0.0		 3v5vA-3sonA:
16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYJ_A_NIZA810_1
(CATALASE-PEROXIDASE)		 3son HYPOTHETICAL NUDIX
HYDROLASE
(Listeria
monocytogenes) 		4 / 6 HIS A 109
LEU A 112
PRO A  11
SER A  53
 None
 1.12A 5syjA-3sonA:
undetectable		 5syjA-3sonA:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYJ_B_NIZB810_1
(CATALASE-PEROXIDASE)		 3son HYPOTHETICAL NUDIX
HYDROLASE
(Listeria
monocytogenes) 		4 / 6 HIS A 109
LEU A 112
PRO A  11
SER A  53
 None
 1.14A 5syjB-3sonA:
undetectable		 5syjB-3sonA:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_B_OAQB302_0
(SULFOTRANSFERASE)		 3son HYPOTHETICAL NUDIX
HYDROLASE
(Listeria
monocytogenes) 		5 / 12 ILE A  10
LEU A 123
VAL A 115
ILE A  13
LEU A 140
 None
 1.15A 5tiwB-3sonA:
undetectable		 5tiwB-3sonA:
20.24