SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3soz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QGT_B_CP6B609_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3soz CYTOPLASMIC PROTEIN
STM1381
(Salmonella
enterica) 		5 / 10 ILE A   6
ALA A  51
PHE A  81
SER A 119
ILE A  73
 None
 1.24A 3qgtB-3sozA:
undetectable		 3qgtB-3sozA:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ROZ_A_NCAA266_0
(APOLIPOPROTEIN
A-I-BINDING PROTEIN)		 3soz CYTOPLASMIC PROTEIN
STM1381
(Salmonella
enterica) 		4 / 6 ASP A  96
LEU A  82
LEU A 134
THR A 132
 None
 1.08A 3rozA-3sozA:
3.7		 3rozA-3sozA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U5J_A_08HA1_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 3soz CYTOPLASMIC PROTEIN
STM1381
(Salmonella
enterica) 		4 / 7 LEU A  98
LEU A 134
ILE A   6
MET A  49
 None
 1.00A 3u5jA-3sozA:
undetectable		 3u5jA-3sozA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UBO_A_ADNA353_1
(ADENOSINE KINASE)		 3soz CYTOPLASMIC PROTEIN
STM1381
(Salmonella
enterica) 		5 / 12 ILE A 123
GLY A 122
ASN A 180
GLU A 150
GLY A 115
 None
 0.95A 3uboA-3sozA:
3.5		 3uboA-3sozA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_B_2FAB401_2
(ADENOSINE KINASE)		 3soz CYTOPLASMIC PROTEIN
STM1381
(Salmonella
enterica) 		4 / 5 ILE A   6
ALA A  97
MET A  49
PHE A  81
 None
 0.78A 4dc3B-3sozA:
3.8		 4dc3B-3sozA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K0B_B_SAMB504_0
(S-ADENOSYLMETHIONINE
SYNTHASE)		 3soz CYTOPLASMIC PROTEIN
STM1381
(Salmonella
enterica) 		4 / 8 ASN A  79
ASP A  75
LEU A 118
ILE A 123
 None
GOL  A1001 (-3.1A)
None
None
 1.05A 4k0bA-3sozA:
undetectable		 4k0bA-3sozA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3soz CYTOPLASMIC PROTEIN
STM1381
(Salmonella
enterica) 		4 / 8 THR A 204
GLY A 108
GLY A 109
VAL A 105
 None
 0.72A 4qvvK-3sozA:
undetectable
4qvvL-3sozA:
undetectable		 4qvvK-3sozA:
21.09
4qvvL-3sozA:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3soz CYTOPLASMIC PROTEIN
STM1381
(Salmonella
enterica) 		4 / 8 THR A 204
GLY A 108
GLY A 109
VAL A 105
 None
 0.71A 4qvvY-3sozA:
undetectable
4qvvZ-3sozA:
undetectable		 4qvvY-3sozA:
21.09
4qvvZ-3sozA:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCV_A_1N1A404_2
(MEMBRANE-ASSOCIATED
TYROSINE- AND
THREONINE-SPECIFIC
CDC2-INHIBITORY
KINASE)		 3soz CYTOPLASMIC PROTEIN
STM1381
(Salmonella
enterica) 		4 / 5 VAL A 133
HIS A 206
LEU A 138
ASP A 103
 None
 1.43A 5vcvA-3sozA:
undetectable		 5vcvA-3sozA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_B_ACRB1431_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 3soz CYTOPLASMIC PROTEIN
STM1381
(Salmonella
enterica) 		4 / 5 HIS A 220
ASP A  75
TRP A 221
GLY A 115
 GOL  A1001 (-3.6A)
GOL  A1001 (-3.1A)
GOL  A1001 (-4.0A)
None
 1.49A 5x7pB-3sozA:
undetectable		 5x7pB-3sozA:
11.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6I5Z_D_SAMD401_0
(O-METHYLTRANSFERASE
1)		 3soz CYTOPLASMIC PROTEIN
STM1381
(Salmonella
enterica) 		5 / 11 GLY A 109
GLY A 208
LEU A 111
VAL A 210
ASP A 103
 None
 1.11A 6i5zD-3sozA:
undetectable		 6i5zD-3sozA:
20.85