SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3sp1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KLM_A_SPPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)		 3sp1 CYSTEINYL-TRNA
SYNTHETASE
(Borreliella
burgdorferi) 		5 / 11 LEU A 137
LYS A 135
VAL A 150
PRO A 215
LEU A 219
 None
 1.42A 1klmA-3sp1A:
undetectable		 1klmA-3sp1A:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE2_A_CUA502_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 3sp1 CYSTEINYL-TRNA
SYNTHETASE
(Borreliella
burgdorferi) 		3 / 3 GLU A 250
HIS A 247
HIS A 246
 ZN  A 481 (-3.9A)
None
ZN  A 481 (-3.3A)
 0.72A 1oe2A-3sp1A:
undetectable		 1oe2A-3sp1A:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QU3_A_MRCA993_1
(ISOLEUCYL-TRNA
SYNTHETASE)		 3sp1 CYSTEINYL-TRNA
SYNTHETASE
(Borreliella
burgdorferi) 		5 / 12 GLY A 238
HIS A 242
SER A 216
PHE A 266
VAL A 267
 AMP  A 482 ( 3.9A)
AMP  A 482 (-4.2A)
None
None
None
 1.44A 1qu3A-3sp1A:
14.6		 1qu3A-3sp1A:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UWJ_B_BAXB1723_2
(B-RAF PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE)		 3sp1 CYSTEINYL-TRNA
SYNTHETASE
(Borreliella
burgdorferi) 		3 / 3 ILE A  44
ASP A 108
PHE A 105
 None
 0.56A 1uwjB-3sp1A:
undetectable		 1uwjB-3sp1A:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_C_CHDC3525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 3sp1 CYSTEINYL-TRNA
SYNTHETASE
(Borreliella
burgdorferi) 		4 / 7 HIS A 242
ASP A  68
THR A  67
HIS A 236
 AMP  A 482 (-4.2A)
None
None
None
 1.46A 1v54A-3sp1A:
undetectable
1v54C-3sp1A:
undetectable		 1v54A-3sp1A:
20.43
1v54C-3sp1A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_C_CHDC3525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 3sp1 CYSTEINYL-TRNA
SYNTHETASE
(Borreliella
burgdorferi) 		4 / 7 HIS A 246
ASP A  68
THR A  67
HIS A 236
 ZN  A 481 (-3.3A)
None
None
None
 1.35A 1v54A-3sp1A:
undetectable
1v54C-3sp1A:
undetectable		 1v54A-3sp1A:
20.43
1v54C-3sp1A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_P_CHDP4525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 3sp1 CYSTEINYL-TRNA
SYNTHETASE
(Borreliella
burgdorferi) 		4 / 7 HIS A 242
ASP A  68
THR A  67
HIS A 236
 AMP  A 482 (-4.2A)
None
None
None
 1.44A 1v54N-3sp1A:
undetectable
1v54P-3sp1A:
undetectable		 1v54N-3sp1A:
20.43
1v54P-3sp1A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_P_CHDP4525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 3sp1 CYSTEINYL-TRNA
SYNTHETASE
(Borreliella
burgdorferi) 		4 / 7 HIS A 246
ASP A  68
THR A  67
HIS A 236
 ZN  A 481 (-3.3A)
None
None
None
 1.35A 1v54N-3sp1A:
undetectable
1v54P-3sp1A:
undetectable		 1v54N-3sp1A:
20.43
1v54P-3sp1A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_C_CHDC3525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 3sp1 CYSTEINYL-TRNA
SYNTHETASE
(Borreliella
burgdorferi) 		4 / 7 HIS A 242
ASP A  68
THR A  67
HIS A 236
 AMP  A 482 (-4.2A)
None
None
None
 1.47A 1v55A-3sp1A:
undetectable
1v55C-3sp1A:
undetectable		 1v55A-3sp1A:
20.43
1v55C-3sp1A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_C_CHDC3525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 3sp1 CYSTEINYL-TRNA
SYNTHETASE
(Borreliella
burgdorferi) 		4 / 7 HIS A 246
ASP A  68
THR A  67
HIS A 236
 ZN  A 481 (-3.3A)
None
None
None
 1.35A 1v55A-3sp1A:
undetectable
1v55C-3sp1A:
undetectable		 1v55A-3sp1A:
20.43
1v55C-3sp1A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z95_A_198A501_2
(ANDROGEN RECEPTOR)		 3sp1 CYSTEINYL-TRNA
SYNTHETASE
(Borreliella
burgdorferi) 		4 / 6 LEU A   5
ASN A   7
LEU A 237
ILE A 243
 None
 0.83A 1z95A-3sp1A:
undetectable		 1z95A-3sp1A:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3sp1 CYSTEINYL-TRNA
SYNTHETASE
(Borreliella
burgdorferi) 		4 / 7 HIS A 242
ASP A  68
THR A  67
HIS A 236
 AMP  A 482 (-4.2A)
None
None
None
 1.46A 2dyrA-3sp1A:
undetectable
2dyrC-3sp1A:
undetectable		 2dyrA-3sp1A:
20.43
2dyrC-3sp1A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3sp1 CYSTEINYL-TRNA
SYNTHETASE
(Borreliella
burgdorferi) 		4 / 7 HIS A 246
ASP A  68
THR A  67
HIS A 236
 ZN  A 481 (-3.3A)
None
None
None
 1.37A 2dyrA-3sp1A:
undetectable
2dyrC-3sp1A:
undetectable		 2dyrA-3sp1A:
20.43
2dyrC-3sp1A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3sp1 CYSTEINYL-TRNA
SYNTHETASE
(Borreliella
burgdorferi) 		4 / 7 HIS A 242
ASP A  68
THR A  67
HIS A 236
 AMP  A 482 (-4.2A)
None
None
None
 1.46A 2dyrN-3sp1A:
0.2
2dyrP-3sp1A:
undetectable		 2dyrN-3sp1A:
20.43
2dyrP-3sp1A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3sp1 CYSTEINYL-TRNA
SYNTHETASE
(Borreliella
burgdorferi) 		4 / 7 HIS A 246
ASP A  68
THR A  67
HIS A 236
 ZN  A 481 (-3.3A)
None
None
None
 1.36A 2dyrN-3sp1A:
0.2
2dyrP-3sp1A:
undetectable		 2dyrN-3sp1A:
20.43
2dyrP-3sp1A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3sp1 CYSTEINYL-TRNA
SYNTHETASE
(Borreliella
burgdorferi) 		4 / 6 HIS A 242
ASP A  68
THR A  67
HIS A 236
 AMP  A 482 (-4.2A)
None
None
None
 1.46A 2dysA-3sp1A:
undetectable
2dysC-3sp1A:
undetectable		 2dysA-3sp1A:
20.43
2dysC-3sp1A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3sp1 CYSTEINYL-TRNA
SYNTHETASE
(Borreliella
burgdorferi) 		4 / 6 HIS A 246
ASP A  68
THR A  67
HIS A 236
 ZN  A 481 (-3.3A)
None
None
None
 1.36A 2dysA-3sp1A:
undetectable
2dysC-3sp1A:
undetectable		 2dysA-3sp1A:
20.43
2dysC-3sp1A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_P_CHDP304_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3sp1 CYSTEINYL-TRNA
SYNTHETASE
(Borreliella
burgdorferi) 		4 / 6 HIS A 242
ASP A  68
THR A  67
HIS A 236
 AMP  A 482 (-4.2A)
None
None
None
 1.44A 2dysN-3sp1A:
undetectable
2dysP-3sp1A:
undetectable		 2dysN-3sp1A:
20.43
2dysP-3sp1A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_P_CHDP304_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3sp1 CYSTEINYL-TRNA
SYNTHETASE
(Borreliella
burgdorferi) 		4 / 6 HIS A 246
ASP A  68
THR A  67
HIS A 236
 ZN  A 481 (-3.3A)
None
None
None
 1.31A 2dysN-3sp1A:
undetectable
2dysP-3sp1A:
undetectable		 2dysN-3sp1A:
20.43
2dysP-3sp1A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3sp1 CYSTEINYL-TRNA
SYNTHETASE
(Borreliella
burgdorferi) 		4 / 7 HIS A 242
ASP A  68
THR A  67
HIS A 236
 AMP  A 482 (-4.2A)
None
None
None
 1.46A 2eijA-3sp1A:
undetectable
2eijC-3sp1A:
undetectable		 2eijA-3sp1A:
20.43
2eijC-3sp1A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3sp1 CYSTEINYL-TRNA
SYNTHETASE
(Borreliella
burgdorferi) 		4 / 7 HIS A 246
ASP A  68
THR A  67
HIS A 236
 ZN  A 481 (-3.3A)
None
None
None
 1.36A 2eijA-3sp1A:
undetectable
2eijC-3sp1A:
undetectable		 2eijA-3sp1A:
20.43
2eijC-3sp1A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3sp1 CYSTEINYL-TRNA
SYNTHETASE
(Borreliella
burgdorferi) 		4 / 7 HIS A 242
ASP A  68
THR A  67
HIS A 236
 AMP  A 482 (-4.2A)
None
None
None
 1.45A 2eijN-3sp1A:
undetectable
2eijP-3sp1A:
undetectable		 2eijN-3sp1A:
20.43
2eijP-3sp1A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3sp1 CYSTEINYL-TRNA
SYNTHETASE
(Borreliella
burgdorferi) 		4 / 7 HIS A 246
ASP A  68
THR A  67
HIS A 236
 ZN  A 481 (-3.3A)
None
None
None
 1.36A 2eijN-3sp1A:
undetectable
2eijP-3sp1A:
undetectable		 2eijN-3sp1A:
20.43
2eijP-3sp1A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3sp1 CYSTEINYL-TRNA
SYNTHETASE
(Borreliella
burgdorferi) 		4 / 7 HIS A 242
ASP A  68
THR A  67
HIS A 236
 AMP  A 482 (-4.2A)
None
None
None
 1.46A 2eikA-3sp1A:
undetectable
2eikC-3sp1A:
undetectable		 2eikA-3sp1A:
20.43
2eikC-3sp1A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3sp1 CYSTEINYL-TRNA
SYNTHETASE
(Borreliella
burgdorferi) 		4 / 7 HIS A 246
ASP A  68
THR A  67
HIS A 236
 ZN  A 481 (-3.3A)
None
None
None
 1.35A 2eikA-3sp1A:
undetectable
2eikC-3sp1A:
undetectable		 2eikA-3sp1A:
20.43
2eikC-3sp1A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3sp1 CYSTEINYL-TRNA
SYNTHETASE
(Borreliella
burgdorferi) 		4 / 7 HIS A 242
ASP A  68
THR A  67
HIS A 236
 AMP  A 482 (-4.2A)
None
None
None
 1.45A 2eikN-3sp1A:
undetectable
2eikP-3sp1A:
undetectable		 2eikN-3sp1A:
20.43
2eikP-3sp1A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3sp1 CYSTEINYL-TRNA
SYNTHETASE
(Borreliella
burgdorferi) 		4 / 7 HIS A 246
ASP A  68
THR A  67
HIS A 236
 ZN  A 481 (-3.3A)
None
None
None
 1.36A 2eikN-3sp1A:
undetectable
2eikP-3sp1A:
undetectable		 2eikN-3sp1A:
20.43
2eikP-3sp1A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3sp1 CYSTEINYL-TRNA
SYNTHETASE
(Borreliella
burgdorferi) 		4 / 7 HIS A 242
ASP A  68
THR A  67
HIS A 236
 AMP  A 482 (-4.2A)
None
None
None
 1.45A 2eilA-3sp1A:
undetectable
2eilC-3sp1A:
undetectable		 2eilA-3sp1A:
20.43
2eilC-3sp1A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3sp1 CYSTEINYL-TRNA
SYNTHETASE
(Borreliella
burgdorferi) 		4 / 7 HIS A 246
ASP A  68
THR A  67
HIS A 236
 ZN  A 481 (-3.3A)
None
None
None
 1.36A 2eilA-3sp1A:
undetectable
2eilC-3sp1A:
undetectable		 2eilA-3sp1A:
20.43
2eilC-3sp1A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3sp1 CYSTEINYL-TRNA
SYNTHETASE
(Borreliella
burgdorferi) 		4 / 7 HIS A 242
ASP A  68
THR A  67
HIS A 236
 AMP  A 482 (-4.2A)
None
None
None
 1.46A 2eilN-3sp1A:
undetectable
2eilP-3sp1A:
undetectable		 2eilN-3sp1A:
20.43
2eilP-3sp1A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3sp1 CYSTEINYL-TRNA
SYNTHETASE
(Borreliella
burgdorferi) 		4 / 7 HIS A 246
ASP A  68
THR A  67
HIS A 236
 ZN  A 481 (-3.3A)
None
None
None
 1.36A 2eilN-3sp1A:
undetectable
2eilP-3sp1A:
undetectable		 2eilN-3sp1A:
20.43
2eilP-3sp1A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_A_CHDA525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3sp1 CYSTEINYL-TRNA
SYNTHETASE
(Borreliella
burgdorferi) 		4 / 6 HIS A 242
ASP A  68
THR A  67
HIS A 236
 AMP  A 482 (-4.2A)
None
None
None
 1.48A 2eimA-3sp1A:
undetectable
2eimC-3sp1A:
undetectable		 2eimA-3sp1A:
20.43
2eimC-3sp1A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_A_CHDA525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3sp1 CYSTEINYL-TRNA
SYNTHETASE
(Borreliella
burgdorferi) 		4 / 6 HIS A 246
ASP A  68
THR A  67
HIS A 236
 ZN  A 481 (-3.3A)
None
None
None
 1.32A 2eimA-3sp1A:
undetectable
2eimC-3sp1A:
undetectable		 2eimA-3sp1A:
20.43
2eimC-3sp1A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3sp1 CYSTEINYL-TRNA
SYNTHETASE
(Borreliella
burgdorferi) 		4 / 6 HIS A 246
ASP A  68
THR A  67
HIS A 236
 ZN  A 481 (-3.3A)
None
None
None
 1.36A 2eimN-3sp1A:
undetectable
2eimP-3sp1A:
undetectable		 2eimN-3sp1A:
20.43
2eimP-3sp1A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3sp1 CYSTEINYL-TRNA
SYNTHETASE
(Borreliella
burgdorferi) 		4 / 6 HIS A 242
ASP A  68
THR A  67
HIS A 236
 AMP  A 482 (-4.2A)
None
None
None
 1.45A 2einA-3sp1A:
undetectable
2einC-3sp1A:
undetectable		 2einA-3sp1A:
20.43
2einC-3sp1A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3sp1 CYSTEINYL-TRNA
SYNTHETASE
(Borreliella
burgdorferi) 		4 / 6 HIS A 246
ASP A  68
THR A  67
HIS A 236
 ZN  A 481 (-3.3A)
None
None
None
 1.34A 2einA-3sp1A:
undetectable
2einC-3sp1A:
undetectable		 2einA-3sp1A:
20.43
2einC-3sp1A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3sp1 CYSTEINYL-TRNA
SYNTHETASE
(Borreliella
burgdorferi) 		4 / 6 HIS A 242
ASP A  68
THR A  67
HIS A 236
 AMP  A 482 (-4.2A)
None
None
None
 1.44A 2einN-3sp1A:
undetectable
2einP-3sp1A:
undetectable		 2einN-3sp1A:
20.43
2einP-3sp1A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3sp1 CYSTEINYL-TRNA
SYNTHETASE
(Borreliella
burgdorferi) 		4 / 6 HIS A 246
ASP A  68
THR A  67
HIS A 236
 ZN  A 481 (-3.3A)
None
None
None
 1.34A 2einN-3sp1A:
undetectable
2einP-3sp1A:
undetectable		 2einN-3sp1A:
20.43
2einP-3sp1A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_A_CHDA1517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3sp1 CYSTEINYL-TRNA
SYNTHETASE
(Borreliella
burgdorferi) 		4 / 7 HIS A 242
ASP A  68
THR A  67
HIS A 236
 AMP  A 482 (-4.2A)
None
None
None
 1.45A 2y69A-3sp1A:
undetectable
2y69C-3sp1A:
undetectable		 2y69A-3sp1A:
20.43
2y69C-3sp1A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_A_CHDA1517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3sp1 CYSTEINYL-TRNA
SYNTHETASE
(Borreliella
burgdorferi) 		4 / 7 HIS A 246
ASP A  68
THR A  67
HIS A 236
 ZN  A 481 (-3.3A)
None
None
None
 1.34A 2y69A-3sp1A:
undetectable
2y69C-3sp1A:
undetectable		 2y69A-3sp1A:
20.43
2y69C-3sp1A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3sp1 CYSTEINYL-TRNA
SYNTHETASE
(Borreliella
burgdorferi) 		4 / 6 HIS A 242
ASP A  68
THR A  67
HIS A 236
 AMP  A 482 (-4.2A)
None
None
None
 1.48A 2zxwA-3sp1A:
undetectable
2zxwC-3sp1A:
undetectable		 2zxwA-3sp1A:
20.43
2zxwC-3sp1A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3sp1 CYSTEINYL-TRNA
SYNTHETASE
(Borreliella
burgdorferi) 		4 / 6 HIS A 242
ASP A  68
THR A  67
HIS A 236
 AMP  A 482 (-4.2A)
None
None
None
 1.46A 2zxwN-3sp1A:
undetectable
2zxwP-3sp1A:
undetectable		 2zxwN-3sp1A:
20.43
2zxwP-3sp1A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3sp1 CYSTEINYL-TRNA
SYNTHETASE
(Borreliella
burgdorferi) 		4 / 7 HIS A 242
ASP A  68
THR A  67
HIS A 236
 AMP  A 482 (-4.2A)
None
None
None
 1.49A 3abkA-3sp1A:
undetectable
3abkC-3sp1A:
undetectable		 3abkA-3sp1A:
20.43
3abkC-3sp1A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3sp1 CYSTEINYL-TRNA
SYNTHETASE
(Borreliella
burgdorferi) 		4 / 7 HIS A 246
ASP A  68
THR A  67
HIS A 236
 ZN  A 481 (-3.3A)
None
None
None
 1.36A 3abkA-3sp1A:
undetectable
3abkC-3sp1A:
undetectable		 3abkA-3sp1A:
20.43
3abkC-3sp1A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3sp1 CYSTEINYL-TRNA
SYNTHETASE
(Borreliella
burgdorferi) 		4 / 7 HIS A 242
ASP A  68
THR A  67
HIS A 236
 AMP  A 482 (-4.2A)
None
None
None
 1.49A 3abkN-3sp1A:
undetectable
3abkP-3sp1A:
undetectable		 3abkN-3sp1A:
20.43
3abkP-3sp1A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3sp1 CYSTEINYL-TRNA
SYNTHETASE
(Borreliella
burgdorferi) 		4 / 7 HIS A 246
ASP A  68
THR A  67
HIS A 236
 ZN  A 481 (-3.3A)
None
None
None
 1.37A 3abkN-3sp1A:
undetectable
3abkP-3sp1A:
undetectable		 3abkN-3sp1A:
20.43
3abkP-3sp1A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3sp1 CYSTEINYL-TRNA
SYNTHETASE
(Borreliella
burgdorferi) 		4 / 7 HIS A 242
ASP A  68
THR A  67
HIS A 236
 AMP  A 482 (-4.2A)
None
None
None
 1.46A 3abmN-3sp1A:
undetectable
3abmP-3sp1A:
undetectable		 3abmN-3sp1A:
20.43
3abmP-3sp1A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3sp1 CYSTEINYL-TRNA
SYNTHETASE
(Borreliella
burgdorferi) 		4 / 7 HIS A 246
ASP A  68
THR A  67
HIS A 236
 ZN  A 481 (-3.3A)
None
None
None
 1.35A 3abmN-3sp1A:
undetectable
3abmP-3sp1A:
undetectable		 3abmN-3sp1A:
20.43
3abmP-3sp1A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3sp1 CYSTEINYL-TRNA
SYNTHETASE
(Borreliella
burgdorferi) 		4 / 6 HIS A 242
ASP A  68
THR A  67
HIS A 236
 AMP  A 482 (-4.2A)
None
None
None
 1.44A 3ag1A-3sp1A:
undetectable
3ag1C-3sp1A:
undetectable		 3ag1A-3sp1A:
20.43
3ag1C-3sp1A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3sp1 CYSTEINYL-TRNA
SYNTHETASE
(Borreliella
burgdorferi) 		4 / 6 HIS A 246
ASP A  68
THR A  67
HIS A 236
 ZN  A 481 (-3.3A)
None
None
None
 1.35A 3ag1A-3sp1A:
undetectable
3ag1C-3sp1A:
undetectable		 3ag1A-3sp1A:
20.43
3ag1C-3sp1A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3sp1 CYSTEINYL-TRNA
SYNTHETASE
(Borreliella
burgdorferi) 		4 / 6 HIS A 242
ASP A  68
THR A  67
HIS A 236
 AMP  A 482 (-4.2A)
None
None
None
 1.47A 3ag1N-3sp1A:
undetectable
3ag1P-3sp1A:
undetectable		 3ag1N-3sp1A:
20.43
3ag1P-3sp1A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3sp1 CYSTEINYL-TRNA
SYNTHETASE
(Borreliella
burgdorferi) 		4 / 6 HIS A 246
ASP A  68
THR A  67
HIS A 236
 ZN  A 481 (-3.3A)
None
None
None
 1.39A 3ag1N-3sp1A:
undetectable
3ag1P-3sp1A:
undetectable		 3ag1N-3sp1A:
20.43
3ag1P-3sp1A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_A_CHDA525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3sp1 CYSTEINYL-TRNA
SYNTHETASE
(Borreliella
burgdorferi) 		4 / 7 HIS A 242
ASP A  68
THR A  67
HIS A 236
 AMP  A 482 (-4.2A)
None
None
None
 1.45A 3ag2A-3sp1A:
undetectable
3ag2C-3sp1A:
undetectable		 3ag2A-3sp1A:
20.43
3ag2C-3sp1A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_A_CHDA525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3sp1 CYSTEINYL-TRNA
SYNTHETASE
(Borreliella
burgdorferi) 		4 / 7 HIS A 246
ASP A  68
THR A  67
HIS A 236
 ZN  A 481 (-3.3A)
None
None
None
 1.36A 3ag2A-3sp1A:
undetectable
3ag2C-3sp1A:
undetectable		 3ag2A-3sp1A:
20.43
3ag2C-3sp1A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3sp1 CYSTEINYL-TRNA
SYNTHETASE
(Borreliella
burgdorferi) 		4 / 7 HIS A 242
ASP A  68
THR A  67
HIS A 236
 AMP  A 482 (-4.2A)
None
None
None
 1.42A 3ag2N-3sp1A:
undetectable
3ag2P-3sp1A:
undetectable		 3ag2N-3sp1A:
20.43
3ag2P-3sp1A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3sp1 CYSTEINYL-TRNA
SYNTHETASE
(Borreliella
burgdorferi) 		4 / 7 HIS A 246
ASP A  68
THR A  67
HIS A 236
 ZN  A 481 (-3.3A)
None
None
None
 1.34A 3ag2N-3sp1A:
undetectable
3ag2P-3sp1A:
undetectable		 3ag2N-3sp1A:
20.43
3ag2P-3sp1A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3sp1 CYSTEINYL-TRNA
SYNTHETASE
(Borreliella
burgdorferi) 		4 / 7 HIS A 242
ASP A  68
THR A  67
HIS A 236
 AMP  A 482 (-4.2A)
None
None
None
 1.49A 3ag3A-3sp1A:
undetectable
3ag3C-3sp1A:
undetectable		 3ag3A-3sp1A:
20.43
3ag3C-3sp1A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3sp1 CYSTEINYL-TRNA
SYNTHETASE
(Borreliella
burgdorferi) 		4 / 7 HIS A 246
ASP A  68
THR A  67
HIS A 236
 ZN  A 481 (-3.3A)
None
None
None
 1.39A 3ag3A-3sp1A:
undetectable
3ag3C-3sp1A:
undetectable		 3ag3A-3sp1A:
20.43
3ag3C-3sp1A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3sp1 CYSTEINYL-TRNA
SYNTHETASE
(Borreliella
burgdorferi) 		4 / 7 HIS A 242
ASP A  68
THR A  67
HIS A 236
 AMP  A 482 (-4.2A)
None
None
None
 1.46A 3ag3N-3sp1A:
undetectable
3ag3P-3sp1A:
undetectable		 3ag3N-3sp1A:
20.43
3ag3P-3sp1A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3sp1 CYSTEINYL-TRNA
SYNTHETASE
(Borreliella
burgdorferi) 		4 / 7 HIS A 246
ASP A  68
THR A  67
HIS A 236
 ZN  A 481 (-3.3A)
None
None
None
 1.36A 3ag3N-3sp1A:
undetectable
3ag3P-3sp1A:
undetectable		 3ag3N-3sp1A:
20.43
3ag3P-3sp1A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3sp1 CYSTEINYL-TRNA
SYNTHETASE
(Borreliella
burgdorferi) 		4 / 7 HIS A 242
ASP A  68
THR A  67
HIS A 236
 AMP  A 482 (-4.2A)
None
None
None
 1.47A 3ag4A-3sp1A:
undetectable
3ag4C-3sp1A:
undetectable		 3ag4A-3sp1A:
20.43
3ag4C-3sp1A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3sp1 CYSTEINYL-TRNA
SYNTHETASE
(Borreliella
burgdorferi) 		4 / 7 HIS A 246
ASP A  68
THR A  67
HIS A 236
 ZN  A 481 (-3.3A)
None
None
None
 1.36A 3ag4A-3sp1A:
undetectable
3ag4C-3sp1A:
undetectable		 3ag4A-3sp1A:
20.43
3ag4C-3sp1A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3sp1 CYSTEINYL-TRNA
SYNTHETASE
(Borreliella
burgdorferi) 		4 / 7 HIS A 242
ASP A  68
THR A  67
HIS A 236
 AMP  A 482 (-4.2A)
None
None
None
 1.44A 3ag4N-3sp1A:
undetectable
3ag4P-3sp1A:
undetectable		 3ag4N-3sp1A:
20.43
3ag4P-3sp1A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3sp1 CYSTEINYL-TRNA
SYNTHETASE
(Borreliella
burgdorferi) 		4 / 7 HIS A 246
ASP A  68
THR A  67
HIS A 236
 ZN  A 481 (-3.3A)
None
None
None
 1.34A 3ag4N-3sp1A:
undetectable
3ag4P-3sp1A:
undetectable		 3ag4N-3sp1A:
20.43
3ag4P-3sp1A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3sp1 CYSTEINYL-TRNA
SYNTHETASE
(Borreliella
burgdorferi) 		4 / 6 HIS A 242
ASP A  68
THR A  67
HIS A 236
 AMP  A 482 (-4.2A)
None
None
None
 1.48A 3asnA-3sp1A:
undetectable
3asnC-3sp1A:
undetectable		 3asnA-3sp1A:
20.43
3asnC-3sp1A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3sp1 CYSTEINYL-TRNA
SYNTHETASE
(Borreliella
burgdorferi) 		4 / 6 HIS A 246
ASP A  68
THR A  67
HIS A 236
 ZN  A 481 (-3.3A)
None
None
None
 1.36A 3asnA-3sp1A:
undetectable
3asnC-3sp1A:
undetectable		 3asnA-3sp1A:
20.43
3asnC-3sp1A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_S_TFPS202_1
(PROTEIN S100-A4)		 3sp1 CYSTEINYL-TRNA
SYNTHETASE
(Borreliella
burgdorferi) 		4 / 6 LEU A   5
SER A  14
ILE A 235
CYH A 263
 None
 1.02A 3ko0S-3sp1A:
undetectable		 3ko0S-3sp1A:
12.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MIH_A_CUA357_0
(PEPTIDYL-GLYCINE
ALPHA-AMIDATING
MONOOXYGENASE)		 3sp1 CYSTEINYL-TRNA
SYNTHETASE
(Borreliella
burgdorferi) 		3 / 3 HIS A 242
HIS A 246
HIS A 247
 AMP  A 482 (-4.2A)
ZN  A 481 (-3.3A)
None
 0.80A 3mihA-3sp1A:
undetectable		 3mihA-3sp1A:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MIH_A_CUA357_0
(PEPTIDYL-GLYCINE
ALPHA-AMIDATING
MONOOXYGENASE)		 3sp1 CYSTEINYL-TRNA
SYNTHETASE
(Borreliella
burgdorferi) 		3 / 3 HIS A 246
HIS A 247
HIS A 242
 ZN  A 481 (-3.3A)
None
AMP  A 482 (-4.2A)
 0.45A 3mihA-3sp1A:
undetectable		 3mihA-3sp1A:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MIH_A_CUA357_0
(PEPTIDYL-GLYCINE
ALPHA-AMIDATING
MONOOXYGENASE)		 3sp1 CYSTEINYL-TRNA
SYNTHETASE
(Borreliella
burgdorferi) 		3 / 3 HIS A 247
HIS A 242
HIS A 246
 None
AMP  A 482 (-4.2A)
ZN  A 481 (-3.3A)
 0.84A 3mihA-3sp1A:
undetectable		 3mihA-3sp1A:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_K_CLMK221_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3sp1 CYSTEINYL-TRNA
SYNTHETASE
(Borreliella
burgdorferi) 		3 / 3 PHE A 266
CYH A 263
HIS A 236
 None
 1.27A 3u9fL-3sp1A:
undetectable		 3u9fL-3sp1A:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BUP_B_SAMB500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 3sp1 CYSTEINYL-TRNA
SYNTHETASE
(Borreliella
burgdorferi) 		3 / 3 HIS A 242
GLU A 250
ASN A  65
 AMP  A 482 (-4.2A)
ZN  A 481 (-3.9A)
ZN  A 481 ( 4.5A)
 0.96A 4bupB-3sp1A:
undetectable		 4bupB-3sp1A:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_D_SAMD601_1
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 3sp1 CYSTEINYL-TRNA
SYNTHETASE
(Borreliella
burgdorferi) 		3 / 3 ASN A  18
ASP A 234
ASP A 231
 None
 0.63A 4obwD-3sp1A:
3.3		 4obwD-3sp1A:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OJB_A_198A1001_2
(ANDROGEN RECEPTOR)		 3sp1 CYSTEINYL-TRNA
SYNTHETASE
(Borreliella
burgdorferi) 		4 / 7 LEU A   5
ASN A   7
LEU A 237
ILE A 243
 None
 0.82A 4ojbA-3sp1A:
undetectable		 4ojbA-3sp1A:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMI_B_EF2B151_1
(CEREBLON ISOFORM 4)		 3sp1 CYSTEINYL-TRNA
SYNTHETASE
(Borreliella
burgdorferi) 		4 / 8 PRO A 215
SER A 124
TRP A 206
TYR A  95
 None
 1.29A 5amiB-3sp1A:
undetectable		 5amiB-3sp1A:
13.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3sp1 CYSTEINYL-TRNA
SYNTHETASE
(Borreliella
burgdorferi) 		4 / 7 HIS A 242
ASP A  68
THR A  67
HIS A 236
 AMP  A 482 (-4.2A)
None
None
None
 1.47A 5b1aN-3sp1A:
undetectable
5b1aP-3sp1A:
undetectable		 5b1aN-3sp1A:
20.43
5b1aP-3sp1A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3sp1 CYSTEINYL-TRNA
SYNTHETASE
(Borreliella
burgdorferi) 		4 / 7 HIS A 246
ASP A  68
THR A  67
HIS A 236
 ZN  A 481 (-3.3A)
None
None
None
 1.36A 5b1aN-3sp1A:
undetectable
5b1aP-3sp1A:
undetectable		 5b1aN-3sp1A:
20.43
5b1aP-3sp1A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3sp1 CYSTEINYL-TRNA
SYNTHETASE
(Borreliella
burgdorferi) 		4 / 7 HIS A 242
ASP A  68
THR A  67
HIS A 236
 AMP  A 482 (-4.2A)
None
None
None
 1.47A 5b1bN-3sp1A:
undetectable
5b1bP-3sp1A:
undetectable		 5b1bN-3sp1A:
20.43
5b1bP-3sp1A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3sp1 CYSTEINYL-TRNA
SYNTHETASE
(Borreliella
burgdorferi) 		4 / 7 HIS A 246
ASP A  68
THR A  67
HIS A 236
 ZN  A 481 (-3.3A)
None
None
None
 1.36A 5b1bN-3sp1A:
undetectable
5b1bP-3sp1A:
undetectable		 5b1bN-3sp1A:
20.43
5b1bP-3sp1A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3sp1 CYSTEINYL-TRNA
SYNTHETASE
(Borreliella
burgdorferi) 		4 / 7 HIS A 246
ASP A  68
THR A  67
HIS A 236
 ZN  A 481 (-3.3A)
None
None
None
 1.39A 5b3sN-3sp1A:
undetectable
5b3sP-3sp1A:
undetectable		 5b3sN-3sp1A:
20.43
5b3sP-3sp1A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_A_P06A801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 3sp1 CYSTEINYL-TRNA
SYNTHETASE
(Borreliella
burgdorferi) 		4 / 7 ILE A  69
GLY A  70
CYH A 221
PHE A 105
 None
None
ZN  A 481 (-2.2A)
None
 1.13A 5hieA-3sp1A:
undetectable		 5hieA-3sp1A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3sp1 CYSTEINYL-TRNA
SYNTHETASE
(Borreliella
burgdorferi) 		4 / 6 HIS A 242
ASP A  68
THR A  67
HIS A 236
 AMP  A 482 (-4.2A)
None
None
None
 1.46A 5x19N-3sp1A:
undetectable
5x19P-3sp1A:
undetectable		 5x19N-3sp1A:
20.43
5x19P-3sp1A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3sp1 CYSTEINYL-TRNA
SYNTHETASE
(Borreliella
burgdorferi) 		4 / 6 HIS A 246
ASP A  68
THR A  67
HIS A 236
 ZN  A 481 (-3.3A)
None
None
None
 1.39A 5x19N-3sp1A:
undetectable
5x19P-3sp1A:
undetectable		 5x19N-3sp1A:
20.43
5x19P-3sp1A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3sp1 CYSTEINYL-TRNA
SYNTHETASE
(Borreliella
burgdorferi) 		4 / 6 HIS A 246
ASP A  68
THR A  67
HIS A 236
 ZN  A 481 (-3.3A)
None
None
None
 1.37A 5x1bN-3sp1A:
undetectable
5x1bP-3sp1A:
undetectable		 5x1bN-3sp1A:
20.43
5x1bP-3sp1A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3sp1 CYSTEINYL-TRNA
SYNTHETASE
(Borreliella
burgdorferi) 		4 / 7 HIS A 246
ASP A  68
THR A  67
HIS A 236
 ZN  A 481 (-3.3A)
None
None
None
 1.40A 5x1fN-3sp1A:
0.2
5x1fP-3sp1A:
undetectable		 5x1fN-3sp1A:
20.43
5x1fP-3sp1A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIO_A_HFGA801_1
(PROLINE-TRNA
SYNTHETASE CLASS II
AARS (YBAK RNA
BINDING DOMAIN PLUS
TRNA SYNTHETASE))		 3sp1 CYSTEINYL-TRNA
SYNTHETASE
(Borreliella
burgdorferi) 		3 / 3 THR A  67
GLU A 220
HIS A 218
 None
 0.85A 5xioA-3sp1A:
undetectable		 5xioA-3sp1A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIQ_B_HFGB1002_1
(PROLYL-TRNA
SYNTHETASE (PRORS))		 3sp1 CYSTEINYL-TRNA
SYNTHETASE
(Borreliella
burgdorferi) 		3 / 3 THR A  67
GLU A 220
HIS A 218
 None
 0.89A 5xiqB-3sp1A:
undetectable		 5xiqB-3sp1A:
23.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIQ_D_HFGD1002_1
(PROLYL-TRNA
SYNTHETASE (PRORS))		 3sp1 CYSTEINYL-TRNA
SYNTHETASE
(Borreliella
burgdorferi) 		3 / 3 THR A  67
GLU A 220
HIS A 218
 None
 0.87A 5xiqD-3sp1A:
undetectable		 5xiqD-3sp1A:
23.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3sp1 CYSTEINYL-TRNA
SYNTHETASE
(Borreliella
burgdorferi) 		4 / 7 HIS A 242
ASP A  68
THR A  67
HIS A 236
 AMP  A 482 (-4.2A)
None
None
None
 1.48A 5zcqN-3sp1A:
undetectable
5zcqP-3sp1A:
undetectable		 5zcqN-3sp1A:
20.43
5zcqP-3sp1A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3sp1 CYSTEINYL-TRNA
SYNTHETASE
(Borreliella
burgdorferi) 		4 / 7 HIS A 246
ASP A  68
THR A  67
HIS A 236
 ZN  A 481 (-3.3A)
None
None
None
 1.36A 5zcqN-3sp1A:
undetectable
5zcqP-3sp1A:
undetectable		 5zcqN-3sp1A:
20.43
5zcqP-3sp1A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NCS_A_ACTA303_0
(N-ACETYLNEURAMINIC
ACID (SIALIC ACID)
SYNTHETASE)		 3sp1 CYSTEINYL-TRNA
SYNTHETASE
(Borreliella
burgdorferi) 		3 / 3 ILE A  69
THR A  67
PRO A 215
 None
 0.64A 6ncsA-3sp1A:
undetectable		 6ncsA-3sp1A:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3sp1 CYSTEINYL-TRNA
SYNTHETASE
(Borreliella
burgdorferi) 		4 / 6 HIS A 242
ASP A  68
THR A  67
HIS A 236
 AMP  A 482 (-4.2A)
None
None
None
 1.45A 6nknA-3sp1A:
0.4
6nknC-3sp1A:
undetectable		 6nknA-3sp1A:
20.43
6nknC-3sp1A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3sp1 CYSTEINYL-TRNA
SYNTHETASE
(Borreliella
burgdorferi) 		4 / 6 HIS A 246
ASP A  68
THR A  67
HIS A 236
 ZN  A 481 (-3.3A)
None
None
None
 1.37A 6nknA-3sp1A:
0.4
6nknC-3sp1A:
undetectable		 6nknA-3sp1A:
20.43
6nknC-3sp1A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3sp1 CYSTEINYL-TRNA
SYNTHETASE
(Borreliella
burgdorferi) 		4 / 7 HIS A 242
ASP A  68
THR A  67
HIS A 236
 AMP  A 482 (-4.2A)
None
None
None
 1.47A 6nmfN-3sp1A:
undetectable
6nmfP-3sp1A:
undetectable		 6nmfN-3sp1A:
20.43
6nmfP-3sp1A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3sp1 CYSTEINYL-TRNA
SYNTHETASE
(Borreliella
burgdorferi) 		4 / 7 HIS A 246
ASP A  68
THR A  67
HIS A 236
 ZN  A 481 (-3.3A)
None
None
None
 1.45A 6nmfN-3sp1A:
undetectable
6nmfP-3sp1A:
undetectable		 6nmfN-3sp1A:
20.43
6nmfP-3sp1A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_C_CHDC303_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3sp1 CYSTEINYL-TRNA
SYNTHETASE
(Borreliella
burgdorferi) 		4 / 6 HIS A 242
ASP A  68
THR A  67
HIS A 236
 AMP  A 482 (-4.2A)
None
None
None
 1.49A 6nmpA-3sp1A:
undetectable
6nmpC-3sp1A:
undetectable		 6nmpA-3sp1A:
20.43
6nmpC-3sp1A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_C_CHDC303_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3sp1 CYSTEINYL-TRNA
SYNTHETASE
(Borreliella
burgdorferi) 		4 / 6 HIS A 246
ASP A  68
THR A  67
HIS A 236
 ZN  A 481 (-3.3A)
None
None
None
 1.41A 6nmpA-3sp1A:
undetectable
6nmpC-3sp1A:
undetectable		 6nmpA-3sp1A:
20.43
6nmpC-3sp1A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_P_CHDP302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3sp1 CYSTEINYL-TRNA
SYNTHETASE
(Borreliella
burgdorferi) 		4 / 7 HIS A 242
ASP A  68
THR A  67
HIS A 236
 AMP  A 482 (-4.2A)
None
None
None
 1.45A 6nmpN-3sp1A:
0.2
6nmpP-3sp1A:
undetectable		 6nmpN-3sp1A:
20.43
6nmpP-3sp1A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_P_CHDP302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3sp1 CYSTEINYL-TRNA
SYNTHETASE
(Borreliella
burgdorferi) 		4 / 7 HIS A 246
ASP A  68
THR A  67
HIS A 236
 ZN  A 481 (-3.3A)
None
None
None
 1.44A 6nmpN-3sp1A:
0.2
6nmpP-3sp1A:
undetectable		 6nmpN-3sp1A:
20.43
6nmpP-3sp1A:
19.49