SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3sr7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_C_NCAC339_0
(ADP-RIBOSYL CYCLASE)		 3sr7 ISOPENTENYL-DIPHOSPH
ATE DELTA-ISOMERASE
(Streptococcus
mutans) 		3 / 3 GLU A 147
ASN A 143
TRP A 160
 None
 1.17A 1r15C-3sr7A:
undetectable		 1r15C-3sr7A:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_F_NCAF369_0
(ADP-RIBOSYL CYCLASE)		 3sr7 ISOPENTENYL-DIPHOSPH
ATE DELTA-ISOMERASE
(Streptococcus
mutans) 		3 / 3 GLU A 147
ASN A 143
TRP A 160
 None
 1.07A 1r15F-3sr7A:
undetectable		 1r15F-3sr7A:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DTT_F_H4BF1005_1
(HYPOTHETICAL PROTEIN
PH0634)		 3sr7 ISOPENTENYL-DIPHOSPH
ATE DELTA-ISOMERASE
(Streptococcus
mutans) 		5 / 9 ILE A  25
ASP A  23
PHE A  22
THR A 230
THR A 231
 None
 1.23A 2dttE-3sr7A:
0.0
2dttF-3sr7A:
0.0		 2dttE-3sr7A:
14.09
2dttF-3sr7A:
14.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_A_BEZA352_0
(D-AMINO-ACID OXIDASE)		 3sr7 ISOPENTENYL-DIPHOSPH
ATE DELTA-ISOMERASE
(Streptococcus
mutans) 		4 / 6 LEU A  27
TYR A 319
ILE A  25
GLY A 266
 None
 0.75A 2du8A-3sr7A:
undetectable		 2du8A-3sr7A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_B_BEZB1352_0
(D-AMINO-ACID OXIDASE)		 3sr7 ISOPENTENYL-DIPHOSPH
ATE DELTA-ISOMERASE
(Streptococcus
mutans) 		4 / 6 LEU A  27
TYR A 319
ILE A  25
GLY A 266
 None
 0.87A 2du8B-3sr7A:
undetectable		 2du8B-3sr7A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADS_A_IMNA2_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3sr7 ISOPENTENYL-DIPHOSPH
ATE DELTA-ISOMERASE
(Streptococcus
mutans) 		5 / 12 PHE A  53
LEU A 248
LEU A 263
PHE A  55
LEU A 112
 None
 1.36A 3adsA-3sr7A:
undetectable		 3adsA-3sr7A:
25.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADX_A_IMNA2_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3sr7 ISOPENTENYL-DIPHOSPH
ATE DELTA-ISOMERASE
(Streptococcus
mutans) 		5 / 12 PHE A  53
LEU A 248
LEU A 263
PHE A  55
LEU A 112
 None
 1.35A 3adxA-3sr7A:
undetectable		 3adxA-3sr7A:
25.27