SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3srt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IW1_A_ASDA1223_1
(CYTOCHROME P450
CYP125)		 3srt MALTOSE
O-ACETYLTRANSFERASE
(Clostridioides
difficile) 		5 / 12 ILE A 144
PHE A  81
VAL A 100
ILE A  60
VAL A  76
 None
 1.10A 3iw1A-3srtA:
undetectable		 3iw1A-3srtA:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_B_DSFB319_1
(GLR4197 PROTEIN)		 3srt MALTOSE
O-ACETYLTRANSFERASE
(Clostridioides
difficile) 		5 / 9 ILE A 156
ILE A 166
VAL A 142
ILE A 148
ILE A 144
 None
 1.03A 3p4wB-3srtA:
undetectable		 3p4wB-3srtA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_D_DSFD319_1
(GLR4197 PROTEIN)		 3srt MALTOSE
O-ACETYLTRANSFERASE
(Clostridioides
difficile) 		5 / 10 ILE A 156
ILE A 166
VAL A 142
ILE A 148
ILE A 144
 None
 1.04A 3p4wD-3srtA:
undetectable		 3p4wD-3srtA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_E_DSFE319_1
(GLR4197 PROTEIN)		 3srt MALTOSE
O-ACETYLTRANSFERASE
(Clostridioides
difficile) 		5 / 10 ILE A 156
ILE A 166
VAL A 142
ILE A 148
ILE A 144
 None
 1.04A 3p4wE-3srtA:
undetectable		 3p4wE-3srtA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GRK_A_KTRA713_1
(LACTOTRANSFERRIN)		 3srt MALTOSE
O-ACETYLTRANSFERASE
(Clostridioides
difficile) 		4 / 5 THR A 149
GLY A 151
VAL A 154
PRO A 167
 None
 1.09A 4grkA-3srtA:
undetectable		 4grkA-3srtA:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YOA_A_017A100_1
(HIV-1 PROTEASE)		 3srt MALTOSE
O-ACETYLTRANSFERASE
(Clostridioides
difficile) 		4 / 6 ASN A 175
THR A 145
THR A 163
VAL A 161
 None
 0.99A 4yoaA-3srtA:
undetectable		 4yoaA-3srtA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4C_A_IPHA903_0
(PROTEIN ARGONAUTE-2)		 3srt MALTOSE
O-ACETYLTRANSFERASE
(Clostridioides
difficile) 		4 / 6 CYH A  86
ILE A  87
GLN A 107
ILE A 138
 None
GOL  A 192 (-3.1A)
GOL  A 192 ( 4.2A)
None
 0.93A 4z4cA-3srtA:
undetectable		 4z4cA-3srtA:
13.27