SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ss7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4001_1
(SERUM ALBUMIN)		 3ss7 D-SERINE DEHYDRATASE
(Escherichia
coli) 		4 / 5 ARG X 120
LYS X 118
ALA X 119
ASP X 108
 None
PLP  X 502 (-1.3A)
None
None
 1.19A 1e7cA-3ss7X:
undetectable		 1e7cA-3ss7X:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EI6_A_PPFA410_1
(PHOSPHONOACETATE
HYDROLASE)		 3ss7 D-SERINE DEHYDRATASE
(Escherichia
coli) 		4 / 5 THR X  32
ASP X 358
HIS X 300
HIS X 407
 None
 1.17A 1ei6A-3ss7X:
3.1		 1ei6A-3ss7X:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JU6_A_LYAA317_1
(THYMIDYLATE SYNTHASE)		 3ss7 D-SERINE DEHYDRATASE
(Escherichia
coli) 		5 / 11 PHE X  67
ILE X 123
ASP X 108
LEU X 111
ALA X 251
 None
 1.35A 1ju6A-3ss7X:
undetectable		 1ju6A-3ss7X:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JU6_D_LYAD315_1
(THYMIDYLATE SYNTHASE)		 3ss7 D-SERINE DEHYDRATASE
(Escherichia
coli) 		5 / 11 PHE X  67
ILE X 123
ASP X 108
LEU X 111
ALA X 251
 None
 1.36A 1ju6D-3ss7X:
undetectable		 1ju6D-3ss7X:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIJ_B_NOVB444_2
(DNA GYRASE SUBUNIT B)		 3ss7 D-SERINE DEHYDRATASE
(Escherichia
coli) 		3 / 3 ASP X  48
PHE X 245
VAL X  42
 None
 0.71A 1kijB-3ss7X:
undetectable		 1kijB-3ss7X:
25.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LH6_A_NIOA155_1
(LEGHEMOGLOBIN A
(NICOTINATE MET))		 3ss7 D-SERINE DEHYDRATASE
(Escherichia
coli) 		4 / 7 PHE X  59
PHE X 158
PHE X 184
HIS X 129
 None
 0.82A 1lh6A-3ss7X:
undetectable		 1lh6A-3ss7X:
16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9Q_A_CHDA459_0
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 3ss7 D-SERINE DEHYDRATASE
(Escherichia
coli) 		4 / 6 ASP X  18
LEU X  19
VAL X  20
ILE X 329
 None
 1.01A 1s9qA-3ss7X:
undetectable		 1s9qA-3ss7X:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TBF_A_VIAA501_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 3ss7 D-SERINE DEHYDRATASE
(Escherichia
coli) 		5 / 9 LEU X  63
LEU X 127
VAL X 250
ALA X 251
LEU X 111
 None
 1.28A 1tbfA-3ss7X:
undetectable		 1tbfA-3ss7X:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_A_CHDA702_0
(FERROCHELATASE)		 3ss7 D-SERINE DEHYDRATASE
(Escherichia
coli) 		4 / 7 ARG X 264
PRO X 277
VAL X 274
MET X 391
 None
PLP  X 502 ( 4.8A)
None
None
 1.21A 2hrcA-3ss7X:
undetectable		 2hrcA-3ss7X:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NPN_A_SAMA4633_0
(PUTATIVE COBALAMIN
SYNTHESIS RELATED
PROTEIN)		 3ss7 D-SERINE DEHYDRATASE
(Escherichia
coli) 		5 / 9 GLY X  74
LEU X  63
TYR X  62
THR X  70
LEU X 150
 None
 1.31A 2npnA-3ss7X:
1.7		 2npnA-3ss7X:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O5Y_H_STRH249_1
(CHIMERIC ANTIBODY
FAB 1E9-DB3)		 3ss7 D-SERINE DEHYDRATASE
(Escherichia
coli) 		4 / 7 GLY X 425
THR X 424
TRP X 422
SER X  79
 PLP  X 502 ( 4.1A)
PLP  X 502 (-3.0A)
None
None
 1.16A 2o5yH-3ss7X:
undetectable
2o5yL-3ss7X:
undetectable		 2o5yH-3ss7X:
19.63
2o5yL-3ss7X:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_A_SAMA300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 3ss7 D-SERINE DEHYDRATASE
(Escherichia
coli) 		5 / 12 GLY X 290
GLY X 247
GLY X 286
LEU X 127
ILE X  77
 None
 0.99A 2oxtA-3ss7X:
undetectable		 2oxtA-3ss7X:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CFL_A_5CHA693_1
(LACTOTRANSFERRIN)		 3ss7 D-SERINE DEHYDRATASE
(Escherichia
coli) 		4 / 4 THR X 424
VAL X 429
GLY X 169
THR X 168
 PLP  X 502 (-3.0A)
None
None
None
 1.06A 3cflA-3ss7X:
undetectable		 3cflA-3ss7X:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GGU_B_017B201_1
(PROTEASE)		 3ss7 D-SERINE DEHYDRATASE
(Escherichia
coli) 		5 / 12 LEU X  22
GLY X 330
GLY X 343
PRO X 306
THR X 307
 None
 0.80A 3gguA-3ss7X:
undetectable		 3gguA-3ss7X:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I5U_B_SAMB401_1
(O-METHYLTRANSFERASE)		 3ss7 D-SERINE DEHYDRATASE
(Escherichia
coli) 		3 / 3 ASP X 358
PHE X 273
SER X 400
 None
 0.88A 3i5uB-3ss7X:
2.0		 3i5uB-3ss7X:
25.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IB2_A_IBPA3960_1
(LACTOTRANSFERRIN)		 3ss7 D-SERINE DEHYDRATASE
(Escherichia
coli) 		4 / 4 GLY X 426
VAL X 429
GLY X 169
THR X 168
 None
 0.60A 3ib2A-3ss7X:
undetectable		 3ib2A-3ss7X:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IK3_A_0LIA1_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 3ss7 D-SERINE DEHYDRATASE
(Escherichia
coli) 		4 / 7 LEU X 246
VAL X 186
ILE X 236
ARG X 181
 None
 1.18A 3ik3A-3ss7X:
undetectable		 3ik3A-3ss7X:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IK3_B_0LIB2_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 3ss7 D-SERINE DEHYDRATASE
(Escherichia
coli) 		4 / 7 LEU X 246
VAL X 186
ILE X 236
ARG X 181
 None
 1.16A 3ik3B-3ss7X:
undetectable		 3ik3B-3ss7X:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_C_THHC643_0
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 3ss7 D-SERINE DEHYDRATASE
(Escherichia
coli) 		5 / 12 GLU X 125
GLY X 121
SER X 241
PHE X 245
ILE X 236
 None
 1.24A 3k13C-3ss7X:
undetectable		 3k13C-3ss7X:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_M_TFPM201_1
(PROTEIN S100-A4)		 3ss7 D-SERINE DEHYDRATASE
(Escherichia
coli) 		4 / 7 GLY X 206
CYH X 233
PHE X 234
GLY X 183
 None
 0.85A 3ko0M-3ss7X:
undetectable
3ko0P-3ss7X:
undetectable		 3ko0M-3ss7X:
12.95
3ko0P-3ss7X:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_P_TFPP201_1
(PROTEIN S100-A4)		 3ss7 D-SERINE DEHYDRATASE
(Escherichia
coli) 		4 / 7 GLY X 183
GLY X 206
CYH X 233
PHE X 234
 None
 0.82A 3ko0M-3ss7X:
undetectable
3ko0P-3ss7X:
undetectable		 3ko0M-3ss7X:
12.95
3ko0P-3ss7X:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NXU_A_RITA600_2
(CYTOCHROME P450 3A4)		 3ss7 D-SERINE DEHYDRATASE
(Escherichia
coli) 		4 / 7 PHE X 348
ILE X 163
LEU X 171
ARG X 242
 None
 0.81A 3nxuA-3ss7X:
undetectable		 3nxuA-3ss7X:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PYY_A_STIA3_2
(V-ABL ABELSON MURINE
LEUKEMIA VIRAL
ONCOGENE HOMOLOG 1
ISOFORM B VARIANT)		 3ss7 D-SERINE DEHYDRATASE
(Escherichia
coli) 		4 / 6 TYR X 124
VAL X 186
ILE X 236
ARG X 181
 None
 1.11A 3pyyA-3ss7X:
undetectable		 3pyyA-3ss7X:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QG2_A_CP6A609_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3ss7 D-SERINE DEHYDRATASE
(Escherichia
coli) 		5 / 10 ALA X 337
ASN X 170
SER X 116
ILE X 117
THR X 335
 None
PLP  X 502 (-3.8A)
PLP  X 502 ( 4.7A)
PLP  X 502 ( 4.9A)
None
 1.47A 3qg2A-3ss7X:
undetectable		 3qg2A-3ss7X:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SPK_A_TPVA100_1
(HIV-1 PROTEASE)		 3ss7 D-SERINE DEHYDRATASE
(Escherichia
coli) 		5 / 11 LEU X  22
ASP X 328
GLY X 343
PRO X 306
THR X 307
 None
 1.10A 3spkA-3ss7X:
undetectable		 3spkA-3ss7X:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AN2_A_EUIA1382_2
(DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 1)		 3ss7 D-SERINE DEHYDRATASE
(Escherichia
coli) 		4 / 4 ASN X 170
SER X 241
LEU X 244
THR X 424
 PLP  X 502 (-3.8A)
None
None
PLP  X 502 (-3.0A)
 1.36A 4an2A-3ss7X:
undetectable		 4an2A-3ss7X:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AWU_A_4CHA503_0
(OXIDOREDUCTASE,
FMN-BINDING)		 3ss7 D-SERINE DEHYDRATASE
(Escherichia
coli) 		4 / 6 TYR X 361
TRP X  27
PHE X 360
PHE X 302
 None
 1.36A 4awuA-3ss7X:
0.6		 4awuA-3ss7X:
25.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_B_CLQB303_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3ss7 D-SERINE DEHYDRATASE
(Escherichia
coli) 		5 / 11 HIS X 205
ILE X 113
GLY X 122
GLY X 121
TYR X 248
 None
 0.91A 4fglA-3ss7X:
undetectable
4fglB-3ss7X:
undetectable		 4fglA-3ss7X:
20.78
4fglB-3ss7X:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOG_A_C2FA302_0
(THYMIDYLATE SYNTHASE)		 3ss7 D-SERINE DEHYDRATASE
(Escherichia
coli) 		5 / 11 SER X 116
ILE X 117
TRP X 422
LEU X 291
GLY X 247
 PLP  X 502 ( 4.7A)
PLP  X 502 ( 4.9A)
None
None
None
 1.32A 4fogA-3ss7X:
undetectable		 4fogA-3ss7X:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOG_C_C2FC302_0
(THYMIDYLATE SYNTHASE)		 3ss7 D-SERINE DEHYDRATASE
(Escherichia
coli) 		5 / 11 SER X 116
ILE X 117
TRP X 422
LEU X 291
GLY X 247
 PLP  X 502 ( 4.7A)
PLP  X 502 ( 4.9A)
None
None
None
 1.36A 4fogC-3ss7X:
undetectable		 4fogC-3ss7X:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0V_D_MIXD101_1
(DNA TOPOISOMERASE
2-BETA)		 3ss7 D-SERINE DEHYDRATASE
(Escherichia
coli) 		4 / 6 ARG X 351
GLY X 350
ASN X  29
GLU X 354
 None
 1.05A 4g0vB-3ss7X:
undetectable		 4g0vB-3ss7X:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_A_CHDA504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3ss7 D-SERINE DEHYDRATASE
(Escherichia
coli) 		4 / 7 ARG X 264
PRO X 277
VAL X 274
MET X 391
 None
PLP  X 502 ( 4.8A)
None
None
 1.22A 4klrA-3ss7X:
undetectable		 4klrA-3ss7X:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RS0_A_IBPA706_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3ss7 D-SERINE DEHYDRATASE
(Escherichia
coli) 		5 / 9 VAL X  42
LEU X  44
LEU X  39
GLY X 285
LEU X 356
 None
 1.05A 4rs0A-3ss7X:
undetectable		 4rs0A-3ss7X:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XJ7_D_ADND303_1
(5'/3'-NUCLEOTIDASE
SURE)		 3ss7 D-SERINE DEHYDRATASE
(Escherichia
coli) 		5 / 10 LEU X 383
GLY X 426
ASP X 108
SER X 116
ILE X 381
 None
None
None
PLP  X 502 ( 4.7A)
None
 1.13A 4xj7C-3ss7X:
undetectable
4xj7D-3ss7X:
undetectable		 4xj7C-3ss7X:
19.61
4xj7D-3ss7X:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_D_SORD1343_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3ss7 D-SERINE DEHYDRATASE
(Escherichia
coli) 		4 / 5 ALA X 196
ARG X 203
ALA X 194
GLU X 211
 None
 1.03A 5a06C-3ss7X:
2.6
5a06D-3ss7X:
2.6		 5a06C-3ss7X:
22.95
5a06D-3ss7X:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESH_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3ss7 D-SERINE DEHYDRATASE
(Escherichia
coli) 		4 / 5 TYR X 248
TRP X 422
LEU X 340
PRO X 277
 None
None
None
PLP  X 502 ( 4.8A)
 1.42A 5eshA-3ss7X:
0.6		 5eshA-3ss7X:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FSA_A_X2NA590_1
(CYP51 VARIANT1)		 3ss7 D-SERINE DEHYDRATASE
(Escherichia
coli) 		5 / 12 ALA X 389
LEU X 272
ILE X 265
PHE X 295
LEU X  81
 None
 0.96A 5fsaA-3ss7X:
undetectable		 5fsaA-3ss7X:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JW1_B_CELB602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3ss7 D-SERINE DEHYDRATASE
(Escherichia
coli) 		5 / 12 LEU X  44
LEU X  39
ALA X  52
GLY X 285
LEU X 356
 None
 0.93A 5jw1B-3ss7X:
0.0		 5jw1B-3ss7X:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWW_A_ACAA18_2
(SCRFP-TAG,GP41)		 3ss7 D-SERINE DEHYDRATASE
(Escherichia
coli) 		3 / 3 LYS X 107
TRP X 422
SER X 109
 None
 1.34A 5nwwA-3ss7X:
undetectable		 5nwwA-3ss7X:
6.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXQ_B_NIZB808_1
(CATALASE-PEROXIDASE)		 3ss7 D-SERINE DEHYDRATASE
(Escherichia
coli) 		4 / 8 ARG X 351
GLU X 354
GLY X 315
THR X 318
 None
 0.98A 5sxqB-3ss7X:
undetectable		 5sxqB-3ss7X:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXT_A_NIZA807_1
(CATALASE-PEROXIDASE)		 3ss7 D-SERINE DEHYDRATASE
(Escherichia
coli) 		4 / 8 GLU X 384
VAL X 429
GLY X 169
LEU X 173
 PLP  X 502 (-3.4A)
None
None
None
 0.96A 5sxtA-3ss7X:
0.1		 5sxtA-3ss7X:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXT_B_NIZB808_1
(CATALASE-PEROXIDASE)		 3ss7 D-SERINE DEHYDRATASE
(Escherichia
coli) 		4 / 8 ARG X 351
GLU X 354
GLY X 315
THR X 318
 None
 1.00A 5sxtB-3ss7X:
undetectable		 5sxtB-3ss7X:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYJ_B_NIZB809_1
(CATALASE-PEROXIDASE)		 3ss7 D-SERINE DEHYDRATASE
(Escherichia
coli) 		4 / 8 ARG X 351
GLU X 354
GLY X 315
THR X 318
 None
 1.00A 5syjB-3ss7X:
0.0		 5syjB-3ss7X:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UXD_B_ZITB501_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E MPHH)		 3ss7 D-SERINE DEHYDRATASE
(Escherichia
coli) 		5 / 12 LEU X 142
ASP X 143
LEU X  63
PHE X 158
GLY X 138
 None
 1.13A 5uxdB-3ss7X:
undetectable		 5uxdB-3ss7X:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VC0_A_RITA602_1
(CYTOCHROME P450 3A4)		 3ss7 D-SERINE DEHYDRATASE
(Escherichia
coli) 		5 / 12 SER X  79
LEU X 276
ALA X 423
ILE X  84
ALA X  83
 None
 1.18A 5vc0A-3ss7X:
undetectable		 5vc0A-3ss7X:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X80_D_SALD201_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 3ss7 D-SERINE DEHYDRATASE
(Escherichia
coli) 		4 / 5 PRO X 284
GLY X 285
TYR X 248
VAL X 280
 PLP  X 502 (-4.2A)
None
None
PLP  X 502 (-3.8A)
 1.33A 5x80C-3ss7X:
undetectable
5x80D-3ss7X:
undetectable		 5x80C-3ss7X:
17.23
5x80D-3ss7X:
17.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A7P_A_9SCA601_0
(SERUM ALBUMIN)		 3ss7 D-SERINE DEHYDRATASE
(Escherichia
coli) 		5 / 12 LEU X 357
PHE X 245
LEU X 171
GLY X 290
LEU X 276
 None
 1.26A 6a7pA-3ss7X:
undetectable		 6a7pA-3ss7X:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_A_ADNA503_1
(ADENOSYLHOMOCYSTEINA
SE)		 3ss7 D-SERINE DEHYDRATASE
(Escherichia
coli) 		3 / 3 LEU X 320
GLN X 323
LYS X   6
 None
 0.95A 6exiB-3ss7X:
3.3		 6exiB-3ss7X:
11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_B_ADNB503_0
(ADENOSYLHOMOCYSTEINA
SE)		 3ss7 D-SERINE DEHYDRATASE
(Escherichia
coli) 		3 / 3 LEU X 320
GLN X 323
LYS X   6
 None
 0.92A 6exiA-3ss7X:
3.4		 6exiA-3ss7X:
11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA806_0
(GEPHYRIN)		 3ss7 D-SERINE DEHYDRATASE
(Escherichia
coli) 		4 / 4 MET X 428
GLY X 427
HIS X 110
GLY X 115
 None
 0.94A 6fgdA-3ss7X:
undetectable		 6fgdA-3ss7X:
25.00