SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3sse'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2NNH_B_9CRB502_1 (CYTOCHROME P450 2C8)	3sse	5-METHYLCYTOSINE-SPE CIFIC RESTRICTION ENZYME B (Escherichia coli)	5 / 10	SER A 3 ILE A 4 ILE A 8 LEU A 141 ASN A 143	None	1.18A	2nnhB-3sseA: undetectable	2nnhB-3sseA: 18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4OLB_A_TRPA901_0 (PROTEIN ARGONAUTE-2)	3sse	5-METHYLCYTOSINE-SPE CIFIC RESTRICTION ENZYME B (Escherichia coli)	3 / 3	VAL A 77 ALA A 123 PHE A 137	None	0.88A	4olbA-3sseA: undetectable	4olbA-3sseA: 11.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4W5N_A_IPHA901_0 (PROTEIN ARGONAUTE-2)	3sse	5-METHYLCYTOSINE-SPE CIFIC RESTRICTION ENZYME B (Escherichia coli)	3 / 3	VAL A 77 ALA A 123 PHE A 137	None	0.92A	4w5nA-3sseA: undetectable	4w5nA-3sseA: 11.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Z4I_A_IPHA903_0 (PROTEIN ARGONAUTE-2)	3sse	5-METHYLCYTOSINE-SPE CIFIC RESTRICTION ENZYME B (Escherichia coli)	3 / 3	VAL A 77 ALA A 123 PHE A 137	None	0.86A	4z4iA-3sseA: undetectable	4z4iA-3sseA: 11.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JS1_A_IPHA902_0 (PROTEIN ARGONAUTE-2)	3sse	5-METHYLCYTOSINE-SPE CIFIC RESTRICTION ENZYME B (Escherichia coli)	3 / 3	VAL A 77 ALA A 123 PHE A 137	None	0.87A	5js1A-3sseA: undetectable	5js1A-3sseA: 11.43

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2NNH_B_9CRB502_1","CYTOCHROME P450 2C8","3sse","5-METHYLCYTOSINE-SPECIFIC RESTRICTION ENZYME B","Escherichia coli",5,"SER A   3;ILE A   4;ILE A   8;LEU A 141;ASN A 143","None","1.18A","2nnhB-3sseA:undetectable","2nnhB-3sseA:18.28"],["4OLB_A_TRPA901_0","PROTEIN ARGONAUTE-2","3sse","5-METHYLCYTOSINE-SPECIFIC RESTRICTION ENZYME B","Escherichia coli",3,"VAL A  77;ALA A 123;PHE A 137","None","0.88A","4olbA-3sseA:undetectable","4olbA-3sseA:11.43"],["4W5N_A_IPHA901_0","PROTEIN ARGONAUTE-2","3sse","5-METHYLCYTOSINE-SPECIFIC RESTRICTION ENZYME B","Escherichia coli",3,"VAL A  77;ALA A 123;PHE A 137","None","0.92A","4w5nA-3sseA:undetectable","4w5nA-3sseA:11.43"],["4Z4I_A_IPHA903_0","PROTEIN ARGONAUTE-2","3sse","5-METHYLCYTOSINE-SPECIFIC RESTRICTION ENZYME B","Escherichia coli",3,"VAL A  77;ALA A 123;PHE A 137","None","0.86A","4z4iA-3sseA:undetectable","4z4iA-3sseA:11.43"],["5JS1_A_IPHA902_0","PROTEIN ARGONAUTE-2","3sse","5-METHYLCYTOSINE-SPECIFIC RESTRICTION ENZYME B","Escherichia coli",3,"VAL A  77;ALA A 123;PHE A 137","None","0.87A","5js1A-3sseA:undetectable","5js1A-3sseA:11.43"]]