SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3stg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_P_ASDP1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 3stg 2-DEHYDRO-3-DEOXYPHO
SPHOOCTONATE
ALDOLASE
(Neisseria
meningitidis) 		4 / 8 LEU A  28
LEU A  32
ALA A  53
PHE A  51
 None
 0.85A 2vcvP-3stgA:
undetectable		 2vcvP-3stgA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_E_ACHE1210_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 3stg 2-DEHYDRO-3-DEOXYPHO
SPHOOCTONATE
ALDOLASE
(Neisseria
meningitidis) 		4 / 7 ILE A  86
VAL A  88
TYR A  38
CYH A  35
 None
 1.33A 2xz5D-3stgA:
undetectable
2xz5E-3stgA:
undetectable		 2xz5D-3stgA:
22.83
2xz5E-3stgA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOC_C_ERYC3402_0
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 3stg 2-DEHYDRO-3-DEOXYPHO
SPHOOCTONATE
ALDOLASE
(Neisseria
meningitidis) 		5 / 12 SER A  54
MET A 144
PHE A 151
ILE A 147
GLU A 224
 None
 1.47A 3aocC-3stgA:
undetectable		 3aocC-3stgA:
13.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CLA_A_CLMA221_0
(TYPE III
CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3stg 2-DEHYDRO-3-DEOXYPHO
SPHOOCTONATE
ALDOLASE
(Neisseria
meningitidis) 		5 / 9 GLN A 109
ASN A 132
LEU A  10
VAL A  17
ILE A 160
 CL  A 270 (-3.8A)
None
None
None
None
 1.49A 3claA-3stgA:
undetectable		 3claA-3stgA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQZ_A_LQZA586_1
(SERUM ALBUMIN)		 3stg 2-DEHYDRO-3-DEOXYPHO
SPHOOCTONATE
ALDOLASE
(Neisseria
meningitidis) 		4 / 6 ARG A 164
ASP A 195
LYS A 134
LYS A  52
 CL  A 269 ( 4.5A)
None
CL  A 270 (-3.1A)
CL  A 270 ( 4.1A)
 1.47A 3jqzA-3stgA:
undetectable		 3jqzA-3stgA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSK_B_ACTB901_0
(PYRANOSE 2-OXIDASE)		 3stg 2-DEHYDRO-3-DEOXYPHO
SPHOOCTONATE
ALDOLASE
(Neisseria
meningitidis) 		4 / 6 SER A  54
GLN A 109
PHE A 222
HIS A 198
 None
CL  A 270 (-3.8A)
CL  A 270 (-4.8A)
CL  A 270 (-4.4A)
 1.30A 3lskB-3stgA:
undetectable		 3lskB-3stgA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSK_D_ACTD901_0
(PYRANOSE 2-OXIDASE)		 3stg 2-DEHYDRO-3-DEOXYPHO
SPHOOCTONATE
ALDOLASE
(Neisseria
meningitidis) 		4 / 6 SER A  54
GLN A 109
PHE A 222
HIS A 198
 None
CL  A 270 (-3.8A)
CL  A 270 (-4.8A)
CL  A 270 (-4.4A)
 1.28A 3lskD-3stgA:
1.0		 3lskD-3stgA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEL_D_QELD2_2
(GLUTAMATE [NMDA]
RECEPTOR SUBUNIT
EPSILON-2)		 3stg 2-DEHYDRO-3-DEOXYPHO
SPHOOCTONATE
ALDOLASE
(Neisseria
meningitidis) 		5 / 9 GLN A 109
ILE A 108
THR A 197
PHE A 222
GLU A 224
 CL  A 270 (-3.8A)
None
None
CL  A 270 (-4.8A)
None
 1.45A 3qelD-3stgA:
1.8		 3qelD-3stgA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S8P_A_SAMA500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 3stg 2-DEHYDRO-3-DEOXYPHO
SPHOOCTONATE
ALDOLASE
(Neisseria
meningitidis) 		3 / 3 HIS A 226
SER A  27
GLU A  26
 None
 0.92A 3s8pA-3stgA:
undetectable		 3s8pA-3stgA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OK1_A_198A1001_1
(ANDROGEN RECEPTOR)		 3stg 2-DEHYDRO-3-DEOXYPHO
SPHOOCTONATE
ALDOLASE
(Neisseria
meningitidis) 		5 / 12 LEU A  18
LEU A 221
GLY A 220
ILE A   5
VAL A 130
 None
 1.15A 4ok1A-3stgA:
undetectable		 4ok1A-3stgA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AJQ_A_DB8A800_2
(SERINE/THREONINE-PRO
TEIN KINASE 10)		 3stg 2-DEHYDRO-3-DEOXYPHO
SPHOOCTONATE
ALDOLASE
(Neisseria
meningitidis) 		4 / 4 VAL A  17
ILE A   3
ASN A   6
VAL A 107
 None
 1.12A 5ajqA-3stgA:
undetectable		 5ajqA-3stgA:
24.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KC4_E_RBFE201_1
(RIBOFLAVIN
TRANSPORTER RIBU)		 3stg 2-DEHYDRO-3-DEOXYPHO
SPHOOCTONATE
ALDOLASE
(Neisseria
meningitidis) 		5 / 12 LEU A 218
ASP A 176
GLY A 179
MET A 183
ASN A  12
 None
 1.34A 5kc4E-3stgA:
undetectable		 5kc4E-3stgA:
24.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_G_EY4G501_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 3stg 2-DEHYDRO-3-DEOXYPHO
SPHOOCTONATE
ALDOLASE
(Neisseria
meningitidis) 		4 / 7 ILE A 193
VAL A  17
PRO A 191
ILE A  50
 None
 1.00A 6cduF-3stgA:
undetectable
6cduG-3stgA:
undetectable		 6cduF-3stgA:
22.16
6cduG-3stgA:
22.16