SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3stp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7L_C_SAMC685_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 3stp GALACTONATE
DEHYDRATASE,
PUTATIVE
(Labrenzia
aggregata) 		4 / 8 GLU A  96
ASP A  90
ASP A 119
ILE A 122
 None
 0.68A 1p7lD-3stpA:
undetectable		 1p7lD-3stpA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7L_C_SAMC885_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 3stp GALACTONATE
DEHYDRATASE,
PUTATIVE
(Labrenzia
aggregata) 		4 / 8 GLU A  96
ASP A  90
ASP A 119
ILE A 122
 None
 0.70A 1p7lC-3stpA:
undetectable		 1p7lC-3stpA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_A_SAMA385_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 3stp GALACTONATE
DEHYDRATASE,
PUTATIVE
(Labrenzia
aggregata) 		4 / 8 GLU A  96
ASP A  90
ASP A 119
ILE A 122
 None
 0.68A 1rg9B-3stpA:
undetectable		 1rg9B-3stpA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_B_SAMB485_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 3stp GALACTONATE
DEHYDRATASE,
PUTATIVE
(Labrenzia
aggregata) 		4 / 8 GLU A  96
ASP A  90
ASP A 119
ILE A 122
 None
 0.68A 1rg9A-3stpA:
undetectable		 1rg9A-3stpA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_C_SAMC585_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 3stp GALACTONATE
DEHYDRATASE,
PUTATIVE
(Labrenzia
aggregata) 		4 / 8 GLU A  96
ASP A  90
ASP A 119
ILE A 122
 None
 0.67A 1rg9D-3stpA:
undetectable		 1rg9D-3stpA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_C_SAMC685_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 3stp GALACTONATE
DEHYDRATASE,
PUTATIVE
(Labrenzia
aggregata) 		4 / 8 GLU A  96
ASP A  90
ASP A 119
ILE A 122
 None
 0.69A 1rg9C-3stpA:
undetectable		 1rg9C-3stpA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACK_A_EDRA999_1
(ACETYLCHOLINESTERASE)		 3stp GALACTONATE
DEHYDRATASE,
PUTATIVE
(Labrenzia
aggregata) 		4 / 7 TYR A 154
GLU A 266
PHE A 338
HIS A 316
 None
MG  A 391 (-2.6A)
None
None
 1.06A 2ackA-3stpA:
undetectable		 2ackA-3stpA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOU_A_CQAA403_0
(HISTAMINE
N-METHYLTRANSFERASE)		 3stp GALACTONATE
DEHYDRATASE,
PUTATIVE
(Labrenzia
aggregata) 		4 / 8 ASP A 124
LYS A 128
GLY A 131
ASP A 369
 None
 0.99A 2aouA-3stpA:
undetectable		 2aouA-3stpA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA4_A_ACHA546_0
(ACETYLCHOLINESTERASE)		 3stp GALACTONATE
DEHYDRATASE,
PUTATIVE
(Labrenzia
aggregata) 		4 / 8 TYR A 154
GLU A 266
PHE A 338
HIS A 316
 None
MG  A 391 (-2.6A)
None
None
 1.08A 2ha4A-3stpA:
undetectable		 2ha4A-3stpA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OIQ_A_STIA1001_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 3stp GALACTONATE
DEHYDRATASE,
PUTATIVE
(Labrenzia
aggregata) 		4 / 5 LEU A  32
LEU A 213
MET A  39
ARG A 192
 None
 1.11A 2oiqA-3stpA:
undetectable		 2oiqA-3stpA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R2V_D_ACTD37_0
(GCN4 LEUCINE ZIPPER)		 3stp GALACTONATE
DEHYDRATASE,
PUTATIVE
(Labrenzia
aggregata) 		3 / 3 LYS A  72
ARG A   9
VAL A  10
 None
 1.11A 2r2vC-3stpA:
undetectable
2r2vD-3stpA:
undetectable		 2r2vC-3stpA:
8.61
2r2vD-3stpA:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7H_C_SAMC530_1
(TYPE I RESTRICTION
ENZYME ECOKI M
PROTEIN)		 3stp GALACTONATE
DEHYDRATASE,
PUTATIVE
(Labrenzia
aggregata) 		3 / 3 TYR A 216
GLU A 266
ASN A 291
 None
MG  A 391 (-2.6A)
None
 1.01A 2y7hC-3stpA:
undetectable		 2y7hC-3stpA:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DFR_A_MTXA164_1
(DIHYDROFOLATE
REDUCTASE)		 3stp GALACTONATE
DEHYDRATASE,
PUTATIVE
(Labrenzia
aggregata) 		5 / 12 LEU A 138
ALA A 299
SER A 335
LEU A 367
ALA A 328
 None
 1.14A 3dfrA-3stpA:
undetectable		 3dfrA-3stpA:
15.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DZG_B_NCAB302_0
(ADP-RIBOSYL CYCLASE
1)		 3stp GALACTONATE
DEHYDRATASE,
PUTATIVE
(Labrenzia
aggregata) 		4 / 7 LEU A 365
ASP A 357
SER A 335
THR A 326
 None
 1.33A 3dzgB-3stpA:
undetectable		 3dzgB-3stpA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FRQ_A_ERYA195_1
(REPRESSOR PROTEIN
MPHR(A))		 3stp GALACTONATE
DEHYDRATASE,
PUTATIVE
(Labrenzia
aggregata) 		4 / 5 ASN A 347
ARG A 292
ASN A 291
HIS A 321
 None
 1.31A 3frqA-3stpA:
undetectable		 3frqA-3stpA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_A_THHA642_1
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 3stp GALACTONATE
DEHYDRATASE,
PUTATIVE
(Labrenzia
aggregata) 		3 / 3 ASN A 194
ASP A 186
ARG A  43
 None
 0.72A 3k13A-3stpA:
9.6		 3k13A-3stpA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_C_THHC643_1
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 3stp GALACTONATE
DEHYDRATASE,
PUTATIVE
(Labrenzia
aggregata) 		3 / 3 ASN A 194
ASP A 186
ARG A  43
 None
 0.95A 3k13C-3stpA:
6.5		 3k13C-3stpA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_C_ZPCC1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3stp GALACTONATE
DEHYDRATASE,
PUTATIVE
(Labrenzia
aggregata) 		5 / 12 ILE A 302
GLU A 336
ILE A 146
HIS A 316
VAL A 293
 None
 1.20A 4a97B-3stpA:
undetectable
4a97C-3stpA:
undetectable		 4a97B-3stpA:
19.64
4a97C-3stpA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FIA_A_0U9A601_1
(CHOLESTEROL
24-HYDROXYLASE)		 3stp GALACTONATE
DEHYDRATASE,
PUTATIVE
(Labrenzia
aggregata) 		5 / 12 TYR A 149
VAL A 148
ALA A 360
GLU A 164
ALA A 168
 None
 1.20A 4fiaA-3stpA:
undetectable		 4fiaA-3stpA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FIA_A_198A602_1
(CHOLESTEROL
24-HYDROXYLASE)		 3stp GALACTONATE
DEHYDRATASE,
PUTATIVE
(Labrenzia
aggregata) 		5 / 12 TYR A 149
VAL A 148
ALA A 360
GLU A 164
ALA A 168
 None
 1.20A 4fiaA-3stpA:
undetectable		 4fiaA-3stpA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_A_SAMA405_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3stp GALACTONATE
DEHYDRATASE,
PUTATIVE
(Labrenzia
aggregata) 		4 / 8 GLU A  96
ASP A  90
ASP A 119
ILE A 122
 None
 0.72A 4kttB-3stpA:
undetectable		 4kttB-3stpA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_C_SAMC404_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3stp GALACTONATE
DEHYDRATASE,
PUTATIVE
(Labrenzia
aggregata) 		4 / 8 GLU A  96
ASP A  90
ASP A 119
ILE A 122
 None
 0.61A 4kttD-3stpA:
undetectable		 4kttD-3stpA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LV9_A_20JA602_1
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 3stp GALACTONATE
DEHYDRATASE,
PUTATIVE
(Labrenzia
aggregata) 		4 / 7 TYR A 323
HIS A 324
ILE A 120
ILE A 296
 None
 0.80A 4lv9A-3stpA:
2.6		 4lv9A-3stpA:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LV9_B_20JB602_1
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 3stp GALACTONATE
DEHYDRATASE,
PUTATIVE
(Labrenzia
aggregata) 		4 / 7 TYR A 323
HIS A 324
ILE A 120
ILE A 296
 None
 0.81A 4lv9B-3stpA:
2.3		 4lv9B-3stpA:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NDN_A_SAMA407_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3stp GALACTONATE
DEHYDRATASE,
PUTATIVE
(Labrenzia
aggregata) 		4 / 8 GLU A  96
ASP A  90
ASP A 119
ILE A 122
 None
 0.73A 4ndnB-3stpA:
undetectable		 4ndnB-3stpA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NDN_C_SAMC405_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3stp GALACTONATE
DEHYDRATASE,
PUTATIVE
(Labrenzia
aggregata) 		4 / 8 GLU A  96
ASP A  90
ASP A 119
ILE A 122
 None
 0.62A 4ndnD-3stpA:
undetectable		 4ndnD-3stpA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVJ_B_478B101_1
(HIV-1 PROTEASE)		 3stp GALACTONATE
DEHYDRATASE,
PUTATIVE
(Labrenzia
aggregata) 		5 / 11 ILE A 122
GLY A  60
ILE A  61
THR A 290
ILE A 296
 None
 0.96A 4rvjA-3stpA:
undetectable		 4rvjA-3stpA:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVJ_D_478D101_1
(HIV-1 PROTEASE)		 3stp GALACTONATE
DEHYDRATASE,
PUTATIVE
(Labrenzia
aggregata) 		5 / 11 ILE A 122
GLY A  60
ILE A  61
THR A 290
ILE A 296
 None
 0.95A 4rvjC-3stpA:
undetectable		 4rvjC-3stpA:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGY_A_ERYA403_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 3stp GALACTONATE
DEHYDRATASE,
PUTATIVE
(Labrenzia
aggregata) 		4 / 6 TYR A 173
ILE A 146
TYR A 323
TYR A 351
 None
 1.48A 5igyA-3stpA:
undetectable		 5igyA-3stpA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IK1_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 3stp GALACTONATE
DEHYDRATASE,
PUTATIVE
(Labrenzia
aggregata) 		4 / 5 LEU A 277
GLY A 265
ASP A 246
ILE A 244
 None
 0.91A 5ik1A-3stpA:
undetectable		 5ik1A-3stpA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T8S_B_SAMB402_0
(S-ADENOSYLMETHIONINE
SYNTHASE)		 3stp GALACTONATE
DEHYDRATASE,
PUTATIVE
(Labrenzia
aggregata) 		4 / 8 GLU A  96
ASP A  90
ASP A 119
ILE A 122
 None
 0.60A 5t8sA-3stpA:
undetectable		 5t8sA-3stpA:
24.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBN_B_SAMB401_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3stp GALACTONATE
DEHYDRATASE,
PUTATIVE
(Labrenzia
aggregata) 		4 / 7 GLU A  96
ASP A  90
ASP A 119
ILE A 122
 None
 0.74A 6fbnA-3stpA:
undetectable		 6fbnA-3stpA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD4_B_STIB602_1
(TYROSINE-PROTEIN
KINASE ABL1)		 3stp GALACTONATE
DEHYDRATASE,
PUTATIVE
(Labrenzia
aggregata) 		5 / 6 LEU A  66
VAL A 134
PHE A 269
MET A 112
GLY A 111
 None
 1.43A 6hd4B-3stpA:
undetectable		 6hd4B-3stpA:
12.50