SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3stt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IBG_H_OBNH1_2
(IGG2B-KAPPA 40-50
FAB (HEAVY CHAIN)
IGG2B-KAPPA 40-50
FAB (LIGHT CHAIN))		 3stt METHYLKETONE
SYNTHASE I
(Solanum
habrochaites) 		4 / 7 THR A  18
HIS A  86
SER A 111
LEU A 223
 DKA  A 266 (-2.9A)
None
None
None
 0.98A 1ibgL-3sttA:
undetectable		 1ibgL-3sttA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT5_A_DVAA6_0
(GRAMICIDIN A)		 3stt METHYLKETONE
SYNTHASE I
(Solanum
habrochaites) 		3 / 3 ALA A 178
VAL A 180
TRP A  24
 None
 0.86A 1nt5A-3sttA:
undetectable		 1nt5A-3sttA:
5.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT5_B_DVAB6_0
(GRAMICIDIN A)		 3stt METHYLKETONE
SYNTHASE I
(Solanum
habrochaites) 		3 / 3 ALA A 178
VAL A 180
TRP A  24
 None
 0.86A 1nt5B-3sttA:
undetectable		 1nt5B-3sttA:
5.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 3stt METHYLKETONE
SYNTHASE I
(Solanum
habrochaites) 		5 / 12 ALA A  87
LEU A  88
VAL A 132
LYS A 127
ALA A 131
 DKA  A 266 (-3.4A)
DKA  A 266 (-4.2A)
None
None
None
 1.15A 1sa1A-3sttA:
3.0
1sa1B-3sttA:
3.1		 1sa1A-3sttA:
21.75
1sa1B-3sttA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 3stt METHYLKETONE
SYNTHASE I
(Solanum
habrochaites) 		5 / 12 ALA A  87
LEU A  88
VAL A 132
LYS A 127
ALA A 131
 DKA  A 266 (-3.4A)
DKA  A 266 (-4.2A)
None
None
None
 1.16A 1sa1C-3sttA:
3.5
1sa1D-3sttA:
3.3		 1sa1C-3sttA:
21.75
1sa1D-3sttA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X8O_A_OINA1314_1
(CHOLINE-BINDING
PROTEIN F)		 3stt METHYLKETONE
SYNTHASE I
(Solanum
habrochaites) 		4 / 5 LYS A 206
ASP A 233
TYR A 264
GLU A 234
 None
 1.40A 2x8oA-3sttA:
undetectable		 2x8oA-3sttA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NK2_X_LDPX433_1
(6-HYDROXY-L-NICOTINE
OXIDASE)		 3stt METHYLKETONE
SYNTHASE I
(Solanum
habrochaites) 		4 / 7 TYR A 202
LEU A  65
LEU A 197
PHE A 109
 None
 1.27A 3nk2X-3sttA:
undetectable		 3nk2X-3sttA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OKX_A_SAMA201_0
(YAEB-LIKE PROTEIN
RPA0152)		 3stt METHYLKETONE
SYNTHASE I
(Solanum
habrochaites) 		5 / 12 LEU A 113
HIS A  21
TYR A  64
SER A  48
LEU A  91
 None
 1.24A 3okxA-3sttA:
undetectable		 3okxA-3sttA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OKX_B_SAMB201_1
(YAEB-LIKE PROTEIN
RPA0152)		 3stt METHYLKETONE
SYNTHASE I
(Solanum
habrochaites) 		5 / 12 LEU A 113
HIS A  21
TYR A  64
SER A  48
LEU A  91
 None
 1.22A 3okxB-3sttA:
undetectable		 3okxB-3sttA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_J_CLMJ221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3stt METHYLKETONE
SYNTHASE I
(Solanum
habrochaites) 		5 / 12 SER A 168
TYR A 165
SER A 241
LEU A 110
HIS A 243
 None
None
None
None
DKA  A 266 (-3.8A)
 1.39A 3u9fJ-3sttA:
undetectable
3u9fK-3sttA:
undetectable		 3u9fJ-3sttA:
21.79
3u9fK-3sttA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_S_CLMS221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3stt METHYLKETONE
SYNTHASE I
(Solanum
habrochaites) 		5 / 12 HIS A 243
SER A 168
TYR A 165
SER A 241
LEU A 110
 DKA  A 266 (-3.8A)
None
None
None
None
 1.43A 3u9fP-3sttA:
undetectable
3u9fS-3sttA:
undetectable		 3u9fP-3sttA:
21.79
3u9fS-3sttA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KN2_A_LYAA304_1
(FOLATE RECEPTOR BETA)		 3stt METHYLKETONE
SYNTHASE I
(Solanum
habrochaites) 		5 / 12 ASP A 242
TYR A 165
SER A  48
HIS A  86
GLY A  90
 None
 1.16A 4kn2A-3sttA:
undetectable		 4kn2A-3sttA:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KN2_C_LYAC304_1
(FOLATE RECEPTOR BETA)		 3stt METHYLKETONE
SYNTHASE I
(Solanum
habrochaites) 		5 / 12 ASP A 242
TYR A 165
SER A  48
HIS A  86
GLY A  90
 None
 1.21A 4kn2C-3sttA:
undetectable		 4kn2C-3sttA:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_D_FOLD301_1
(FOLATE RECEPTOR
ALPHA)		 3stt METHYLKETONE
SYNTHASE I
(Solanum
habrochaites) 		3 / 3 HIS A  86
TRP A  24
SER A 111
 None
 0.94A 4lrhD-3sttA:
undetectable		 4lrhD-3sttA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_A_ADNA401_1
(ADENOSINE KINASE)		 3stt METHYLKETONE
SYNTHASE I
(Solanum
habrochaites) 		5 / 12 LEU A  83
GLY A 203
ALA A 107
ASN A 230
GLY A 116
 None
 1.12A 4n09A-3sttA:
5.0		 4n09A-3sttA:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QCK_A_ASDA404_1
(3-KETOSTEROID-9-ALPH
A-MONOOXYGENASE
OXYGENASE SUBUNIT)		 3stt METHYLKETONE
SYNTHASE I
(Solanum
habrochaites) 		5 / 12 ASN A 163
LEU A  88
LEU A 153
ASN A 138
GLY A 129
 None
DKA  A 266 (-4.2A)
None
None
DKA  A 266 ( 3.7A)
 1.12A 4qckA-3sttA:
undetectable		 4qckA-3sttA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_A_GCSA301_1
(CHITOSANASE)		 3stt METHYLKETONE
SYNTHASE I
(Solanum
habrochaites) 		3 / 3 TYR A 202
GLY A 116
PRO A 117
 None
 0.71A 4qwpA-3sttA:
undetectable		 4qwpA-3sttA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JW1_A_CELA602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3stt METHYLKETONE
SYNTHASE I
(Solanum
habrochaites) 		4 / 6 VAL A 208
LEU A 258
SER A 259
PHE A 254
 None
 0.90A 5jw1A-3sttA:
undetectable		 5jw1A-3sttA:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_C_CHDC401_0
(BILE SALT HYDROLASE)		 3stt METHYLKETONE
SYNTHASE I
(Solanum
habrochaites) 		4 / 8 LEU A 183
TYR A 186
ILE A 191
LEU A  68
 None
 0.78A 5y7pC-3sttA:
undetectable		 5y7pC-3sttA:
22.78