SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3su8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DDR_B_MTXB200_1
(DIHYDROFOLATE
REDUCTASE)		 3su8 PLEXIN-B1
(Homo
sapiens) 		5 / 12 ILE X2056
ASP X1959
LEU X1958
PHE X1955
LEU X1981
 None
 1.22A 1ddrB-3su8X:
undetectable		 1ddrB-3su8X:
14.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FE2_A_LAXA700_2
(PROSTAGLANDIN
ENDOPEROXIDE H
SYNTHASE-1)		 3su8 PLEXIN-B1
(Homo
sapiens) 		5 / 12 LEU X1640
PHE X1577
GLY X2083
ALA X2084
LEU X1603
 None
 0.82A 1fe2A-3su8X:
undetectable		 1fe2A-3su8X:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_G_BEZG1162_0
(PEROXIREDOXIN 5)		 3su8 PLEXIN-B1
(Homo
sapiens) 		4 / 8 PRO X1584
PRO X1578
GLY X1579
LEU X1640
 None
 0.83A 1h4oG-3su8X:
undetectable		 1h4oG-3su8X:
13.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LZX_B_H4BB1760_1
(NITRIC-OXIDE
SYNTHASE)		 3su8 PLEXIN-B1
(Homo
sapiens) 		4 / 7 PHE X1954
GLU X1684
MET X1675
TRP X1976
 None
 1.50A 1lzxA-3su8X:
undetectable
1lzxB-3su8X:
undetectable		 1lzxA-3su8X:
22.38
1lzxB-3su8X:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMW_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3su8 PLEXIN-B1
(Homo
sapiens) 		4 / 7 MET X1675
TRP X1976
PHE X1954
GLU X1684
 None
 1.48A 1mmwA-3su8X:
undetectable
1mmwB-3su8X:
undetectable		 1mmwA-3su8X:
22.38
1mmwB-3su8X:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OM4_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3su8 PLEXIN-B1
(Homo
sapiens) 		4 / 7 PHE X1954
GLU X1684
MET X1675
TRP X1976
 None
 1.43A 1om4A-3su8X:
0.2
1om4B-3su8X:
undetectable		 1om4A-3su8X:
22.42
1om4B-3su8X:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3su8 PLEXIN-B1
(Homo
sapiens) 		4 / 7 PHE X1954
GLU X1684
MET X1675
TRP X1976
 None
 1.40A 1p6kA-3su8X:
undetectable
1p6kB-3su8X:
undetectable		 1p6kA-3su8X:
21.27
1p6kB-3su8X:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TDR_A_MTXA170_1
(TELLUROMETHIONYL
DIHYDROFOLATE
REDUCTASE)		 3su8 PLEXIN-B1
(Homo
sapiens) 		5 / 12 ILE X2056
ASP X1959
LEU X1958
PHE X1955
LEU X1981
 None
 1.18A 1tdrA-3su8X:
undetectable		 1tdrA-3su8X:
14.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HJH_A_NCAA900_0
(NAD-DEPENDENT
HISTONE DEACETYLASE
SIR2)		 3su8 PLEXIN-B1
(Homo
sapiens) 		4 / 5 ILE X2103
PHE X1615
PHE X1619
ILE X2124
 None
 0.95A 2hjhA-3su8X:
undetectable		 2hjhA-3su8X:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_B_RIMB299_1
(MATRIX PROTEIN 2)		 3su8 PLEXIN-B1
(Homo
sapiens) 		4 / 6 LEU X1958
ASP X1959
ILE X2056
ARG X2057
 None
 1.17A 2rlfB-3su8X:
undetectable
2rlfC-3su8X:
undetectable		 2rlfB-3su8X:
6.09
2rlfC-3su8X:
6.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VL2_B_BEZB1162_0
(PEROXIREDOXIN-5)		 3su8 PLEXIN-B1
(Homo
sapiens) 		4 / 7 PRO X1584
PRO X1578
GLY X1579
LEU X1640
 None
 0.79A 2vl2B-3su8X:
undetectable		 2vl2B-3su8X:
15.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZI9_A_CL9A401_2
(DEOXYCYTIDINE KINASE)		 3su8 PLEXIN-B1
(Homo
sapiens) 		3 / 3 ASP X1934
PHE X1937
LEU X1941
 None
 0.63A 2zi9A-3su8X:
1.3		 2zi9A-3su8X:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3su8 PLEXIN-B1
(Homo
sapiens) 		4 / 7 MET X1675
TRP X1976
PHE X1954
GLU X1684
 None
 1.48A 3hspA-3su8X:
undetectable
3hspB-3su8X:
undetectable		 3hspA-3su8X:
22.42
3hspB-3su8X:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3su8 PLEXIN-B1
(Homo
sapiens) 		4 / 7 PHE X1954
GLU X1684
MET X1675
TRP X1976
 None
 1.45A 3jt4A-3su8X:
0.4
3jt4B-3su8X:
undetectable		 3jt4A-3su8X:
22.42
3jt4B-3su8X:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBG_C_ACTC800_0
(FAD-LINKED
SULFHYDRYL OXIDASE
ALR)		 3su8 PLEXIN-B1
(Homo
sapiens) 		3 / 3 ASP X2055
ARG X2051
ALA X2054
 None
 0.62A 3mbgC-3su8X:
undetectable		 3mbgC-3su8X:
12.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_B_NIMB1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3su8 PLEXIN-B1
(Homo
sapiens) 		5 / 12 LEU X1640
LEU X1610
PHE X1577
GLY X2083
ALA X2084
 None
 1.08A 3n8xB-3su8X:
undetectable		 3n8xB-3su8X:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_B_DSFB319_1
(GLR4197 PROTEIN)		 3su8 PLEXIN-B1
(Homo
sapiens) 		5 / 9 PRO X1706
ILE X1940
VAL X1699
ILE X1990
ILE X1989
 None
 1.17A 3p4wB-3su8X:
undetectable		 3p4wB-3su8X:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_D_DSFD319_1
(GLR4197 PROTEIN)		 3su8 PLEXIN-B1
(Homo
sapiens) 		5 / 10 PRO X1706
ILE X1940
VAL X1699
ILE X1990
ILE X1989
 None
 1.17A 3p4wD-3su8X:
undetectable		 3p4wD-3su8X:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_E_DSFE319_1
(GLR4197 PROTEIN)		 3su8 PLEXIN-B1
(Homo
sapiens) 		5 / 10 PRO X1706
ILE X1940
VAL X1699
ILE X1990
ILE X1989
 None
 1.19A 3p4wE-3su8X:
undetectable		 3p4wE-3su8X:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNI_B_SALB1345_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3su8 PLEXIN-B1
(Homo
sapiens) 		4 / 8 LEU X1981
PHE X1955
VAL X2049
LEU X1941
 None
 0.85A 3uniB-3su8X:
3.1		 3uniB-3su8X:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_C_ADNC301_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 3su8 PLEXIN-B1
(Homo
sapiens) 		5 / 9 ALA X2013
LEU X1710
LEU X2009
LEU X1734
ILE X1714
 None
 1.05A 3wdmC-3su8X:
undetectable		 3wdmC-3su8X:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX6_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3su8 PLEXIN-B1
(Homo
sapiens) 		4 / 7 PHE X1954
GLU X1684
MET X1675
TRP X1976
 None
 1.49A 4cx6A-3su8X:
undetectable
4cx6B-3su8X:
undetectable		 4cx6A-3su8X:
22.58
4cx6B-3su8X:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVW_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3su8 PLEXIN-B1
(Homo
sapiens) 		4 / 7 PHE X1954
GLU X1684
MET X1675
TRP X1976
 None
 1.43A 4fvwA-3su8X:
undetectable
4fvwB-3su8X:
undetectable		 4fvwA-3su8X:
22.42
4fvwB-3su8X:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVY_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3su8 PLEXIN-B1
(Homo
sapiens) 		4 / 7 PHE X1954
GLU X1684
MET X1675
TRP X1976
 None
 1.45A 4fvyA-3su8X:
undetectable
4fvyB-3su8X:
undetectable		 4fvyA-3su8X:
22.42
4fvyB-3su8X:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GQE_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3su8 PLEXIN-B1
(Homo
sapiens) 		4 / 7 PHE X1954
GLU X1684
MET X1675
TRP X1976
 None
 1.47A 4gqeA-3su8X:
undetectable
4gqeB-3su8X:
undetectable		 4gqeA-3su8X:
22.42
4gqeB-3su8X:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I1N_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3su8 PLEXIN-B1
(Homo
sapiens) 		5 / 11 ILE X2056
ASP X1959
LEU X1958
PHE X1955
LEU X1981
 None
 1.21A 4i1nA-3su8X:
undetectable		 4i1nA-3su8X:
14.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KIC_B_SAMB401_1
(METHYLTRANSFERASE
MPPJ)		 3su8 PLEXIN-B1
(Homo
sapiens) 		3 / 3 ARG X1712
ASP X1998
ASP X1567
 None
 0.86A 4kicB-3su8X:
undetectable		 4kicB-3su8X:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O7G_A_ASCA303_0
(PROBABLE
TRANSMEMBRANE
ASCORBATE
FERRIREDUCTASE 2)		 3su8 PLEXIN-B1
(Homo
sapiens) 		4 / 7 PHE X1652
ILE X1693
TYR X1568
PHE X1576
 None
 1.24A 4o7gA-3su8X:
undetectable
4o7gB-3su8X:
undetectable		 4o7gA-3su8X:
16.92
4o7gB-3su8X:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P65_A_IPHA101_0
(INSULIN)		 3su8 PLEXIN-B1
(Homo
sapiens) 		5 / 10 HIS X2089
LEU X2088
ALA X2087
LEU X1589
LEU X1585
 None
 1.21A 4p65A-3su8X:
undetectable
4p65B-3su8X:
undetectable
4p65F-3su8X:
undetectable
4p65H-3su8X:
undetectable		 4p65A-3su8X:
3.36
4p65B-3su8X:
7.45
4p65F-3su8X:
7.45
4p65H-3su8X:
7.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P65_E_IPHE101_0
(INSULIN)		 3su8 PLEXIN-B1
(Homo
sapiens) 		5 / 11 HIS X2089
LEU X2088
ALA X2087
LEU X1589
LEU X1585
 None
 1.00A 4p65E-3su8X:
undetectable
4p65F-3su8X:
undetectable
4p65J-3su8X:
undetectable
4p65L-3su8X:
undetectable		 4p65E-3su8X:
3.36
4p65F-3su8X:
7.45
4p65J-3su8X:
7.45
4p65L-3su8X:
7.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QLF_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3su8 PLEXIN-B1
(Homo
sapiens) 		5 / 11 ILE X2056
ASP X1959
LEU X1958
PHE X1955
LEU X1981
 None
 1.19A 4qlfA-3su8X:
undetectable		 4qlfA-3su8X:
14.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH5_B_H4BB760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 3su8 PLEXIN-B1
(Homo
sapiens) 		4 / 7 PHE X1954
GLU X1684
MET X1675
TRP X1976
 None
 1.47A 4uh5A-3su8X:
undetectable
4uh5B-3su8X:
undetectable		 4uh5A-3su8X:
22.58
4uh5B-3su8X:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVU_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3su8 PLEXIN-B1
(Homo
sapiens) 		4 / 7 PHE X1954
GLU X1684
MET X1675
TRP X1976
 None
 1.41A 5fvuA-3su8X:
undetectable
5fvuB-3su8X:
2.0		 5fvuA-3su8X:
22.58
5fvuB-3su8X:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVV_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3su8 PLEXIN-B1
(Homo
sapiens) 		4 / 7 PHE X1954
GLU X1684
MET X1675
TRP X1976
 None
 1.42A 5fvvA-3su8X:
undetectable
5fvvB-3su8X:
undetectable		 5fvvA-3su8X:
22.58
5fvvB-3su8X:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVW_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3su8 PLEXIN-B1
(Homo
sapiens) 		4 / 7 PHE X1954
GLU X1684
MET X1675
TRP X1976
 None
 1.45A 5fvwA-3su8X:
undetectable
5fvwB-3su8X:
undetectable		 5fvwA-3su8X:
22.58
5fvwB-3su8X:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1806_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3su8 PLEXIN-B1
(Homo
sapiens) 		4 / 6 ILE X1620
ILE X2103
LEU X2121
PHE X1615
 None
 1.04A 5vkqB-3su8X:
1.8
5vkqC-3su8X:
1.9		 5vkqB-3su8X:
16.91
5vkqC-3su8X:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1807_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3su8 PLEXIN-B1
(Homo
sapiens) 		4 / 6 ILE X1620
ILE X2103
LEU X2121
PHE X1615
 None
 1.04A 5vkqC-3su8X:
1.9
5vkqD-3su8X:
1.9		 5vkqC-3su8X:
16.91
5vkqD-3su8X:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV5_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3su8 PLEXIN-B1
(Homo
sapiens) 		4 / 7 PHE X1954
GLU X1684
MET X1675
TRP X1976
 None
 1.43A 5vv5A-3su8X:
undetectable
5vv5B-3su8X:
undetectable		 5vv5A-3su8X:
22.58
5vv5B-3su8X:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XOO_B_ADNB503_1
(GLYCOSAMINOGLYCAN
XYLOSYLKINASE)		 3su8 PLEXIN-B1
(Homo
sapiens) 		4 / 5 LEU X1660
VAL X1683
GLU X1684
LEU X1676
 None
 1.03A 5xooB-3su8X:
undetectable		 5xooB-3su8X:
9.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUR_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3su8 PLEXIN-B1
(Homo
sapiens) 		4 / 7 MET X1675
TRP X1976
PHE X1954
GLU X1684
 None
 1.49A 6aurA-3su8X:
undetectable
6aurB-3su8X:
undetectable		 6aurA-3su8X:
9.48
6aurB-3su8X:
9.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV3_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3su8 PLEXIN-B1
(Homo
sapiens) 		4 / 7 PHE X1954
GLU X1684
MET X1675
TRP X1976
 None
 1.47A 6av3A-3su8X:
undetectable
6av3B-3su8X:
undetectable		 6av3A-3su8X:
8.49
6av3B-3su8X:
8.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV5_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3su8 PLEXIN-B1
(Homo
sapiens) 		4 / 7 MET X1675
TRP X1976
PHE X1954
GLU X1684
 None
 1.47A 6av5A-3su8X:
undetectable
6av5B-3su8X:
undetectable		 6av5A-3su8X:
8.49
6av5B-3su8X:
8.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_A_HISA402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 3su8 PLEXIN-B1
(Homo
sapiens) 		5 / 10 GLY X1844
VAL X1841
VAL X1805
VAL X1771
ALA X1780
 None
 1.14A 6czmA-3su8X:
undetectable
6czmC-3su8X:
undetectable		 6czmA-3su8X:
21.61
6czmC-3su8X:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DYO_A_LDPA901_0
(EBONY)		 3su8 PLEXIN-B1
(Homo
sapiens) 		4 / 5 VAL X2070
LEU X2074
HIS X1646
THR X1697
 None
 1.12A 6dyoA-3su8X:
undetectable		 6dyoA-3su8X:
8.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD6_A_STIA603_1
(TYROSINE-PROTEIN
KINASE ABL1)		 3su8 PLEXIN-B1
(Homo
sapiens) 		4 / 5 LEU X2037
TYR X2038
MET X1925
GLY X1927
 None
 1.05A 6hd6A-3su8X:
undetectable		 6hd6A-3su8X:
7.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_C_AM2C301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 3su8 PLEXIN-B1
(Homo
sapiens) 		4 / 8 ASP X2055
HIS X1974
ARG X2051
GLU X2050
 None
 1.32A 6mn4C-3su8X:
undetectable		 6mn4C-3su8X:
17.72