SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3suc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J7K_A_ACTA701_0
(HOLLIDAY JUNCTION
DNA HELICASE RUVB)		 3suc PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		4 / 4 GLY A 248
LEU A 249
GLY A 247
ARG A 222
 None
 1.49A 1j7kA-3sucA:
undetectable		 1j7kA-3sucA:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ME7_A_MOAA600_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 3suc PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		4 / 8 SER A 491
ASN A 519
ILE A 518
GLY A 468
 None
 0.72A 1me7A-3sucA:
undetectable		 1me7A-3sucA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MEI_A_MOAA600_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 3suc PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		4 / 8 SER A 491
ASN A 519
ILE A 518
GLY A 468
 None
 0.68A 1meiA-3sucA:
undetectable		 1meiA-3sucA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R5L_A_VIVA301_0
(PROTEIN
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN))		 3suc PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		5 / 12 ILE A 381
ILE A 292
VAL A 318
ILE A 332
ILE A 282
 None
 1.34A 1r5lA-3sucA:
undetectable		 1r5lA-3sucA:
15.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E1Q_A_SALA2006_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3suc PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		4 / 6 ARG A 537
THR A 534
VAL A 535
LEU A 514
 None
 1.04A 2e1qA-3sucA:
undetectable		 2e1qA-3sucA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E1Q_C_SALC4006_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3suc PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		4 / 6 ARG A 537
THR A 534
VAL A 535
LEU A 514
 None
 0.95A 2e1qC-3sucA:
undetectable		 2e1qC-3sucA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I91_A_ACTA601_0
(60 KDA SS-A/RO
RIBONUCLEOPROTEIN)		 3suc PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		4 / 7 SER A 591
SER A 590
SER A 607
THR A 606
 None
 1.08A 2i91A-3sucA:
undetectable		 2i91A-3sucA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_B_RALB600_2
(ESTROGEN RECEPTOR)		 3suc PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		4 / 4 LEU A 419
THR A 420
ILE A 348
HIS A 351
 None
 1.36A 2jfaB-3sucA:
undetectable		 2jfaB-3sucA:
14.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OA1_B_ADNB2005_1
(TRYPTOPHAN
HALOGENASE)		 3suc PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		4 / 7 GLY A 464
GLY A 465
VAL A 436
ARG A 441
 None
 0.77A 2oa1B-3sucA:
undetectable		 2oa1B-3sucA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OPX_A_DXCA1002_0
(ALDEHYDE
DEHYDROGENASE A)		 3suc PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		3 / 3 GLY A 213
ARG A 215
TYR A 251
 None
 0.51A 2opxA-3sucA:
undetectable		 2opxA-3sucA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_D_SAMD300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 3suc PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		6 / 12 GLY A 366
GLY A 257
GLY A 255
GLY A 338
THR A 258
VAL A 376
 None
 1.25A 2oxtD-3sucA:
undetectable		 2oxtD-3sucA:
16.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q83_B_ADNB2_1
(YTAA PROTEIN)		 3suc PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		4 / 6 ILE A 121
PRO A 150
LEU A 155
ILE A 128
 None
 0.92A 2q83B-3sucA:
undetectable		 2q83B-3sucA:
16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AX7_A_SALA1336_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3suc PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		4 / 8 ARG A 537
THR A 534
VAL A 535
LEU A 514
 None
 0.92A 3ax7A-3sucA:
undetectable		 3ax7A-3sucA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_H_SVRH511_3
(PHOSPHOLIPASE A2)		 3suc PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		4 / 7 VAL A 382
ILE A 332
GLY A 331
ARG A 358
 None
 0.90A 3bjwH-3sucA:
undetectable		 3bjwH-3sucA:
11.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EIG_A_MTXA200_2
(DIHYDROFOLATE
REDUCTASE)		 3suc PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		4 / 5 ARG A 807
ILE A 808
VAL A 851
THR A 734
 None
 1.23A 3eigA-3sucA:
undetectable		 3eigA-3sucA:
13.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_A_TRPA1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3suc PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		5 / 10 GLY A 469
GLN A 437
ILE A 489
VAL A 496
VAL A 472
 None
 1.04A 3fhjA-3sucA:
undetectable		 3fhjA-3sucA:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_B_TRPB1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3suc PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		5 / 10 GLY A 469
GLN A 437
ILE A 489
VAL A 496
VAL A 472
 None
 1.08A 3fhjB-3sucA:
undetectable		 3fhjB-3sucA:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_C_TRPC1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3suc PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		5 / 10 GLY A 469
GLN A 437
ILE A 489
VAL A 496
VAL A 472
 None
 1.09A 3fhjC-3sucA:
undetectable		 3fhjC-3sucA:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_E_TRPE1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3suc PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		5 / 10 GLY A 469
GLN A 437
ILE A 489
VAL A 496
VAL A 472
 None
 1.12A 3fhjE-3sucA:
undetectable		 3fhjE-3sucA:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_A_TRPA1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3suc PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		5 / 9 GLY A 469
GLN A 437
ILE A 489
VAL A 496
VAL A 472
 None
 1.04A 3fi0A-3sucA:
undetectable		 3fi0A-3sucA:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_C_TRPC1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3suc PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		5 / 9 GLY A 469
GLN A 437
ILE A 489
VAL A 496
VAL A 472
 None
 1.08A 3fi0C-3sucA:
undetectable		 3fi0C-3sucA:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_D_TRPD1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3suc PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		5 / 9 GLY A 469
GLN A 437
ILE A 489
VAL A 496
VAL A 472
 None
 1.08A 3fi0D-3sucA:
undetectable		 3fi0D-3sucA:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_H_TRPH1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3suc PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		5 / 9 GLY A 469
GLN A 437
ILE A 489
VAL A 496
VAL A 472
 None
 1.08A 3fi0H-3sucA:
undetectable		 3fi0H-3sucA:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_K_TRPK1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3suc PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		5 / 9 GLY A 469
GLN A 437
ILE A 489
VAL A 496
VAL A 472
 None
 1.10A 3fi0K-3sucA:
undetectable		 3fi0K-3sucA:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_L_TRPL1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3suc PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		5 / 9 GLY A 469
GLN A 437
ILE A 489
VAL A 496
VAL A 472
 None
 1.08A 3fi0L-3sucA:
undetectable		 3fi0L-3sucA:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_M_TRPM1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3suc PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		5 / 9 GLY A 469
GLN A 437
ILE A 489
VAL A 496
VAL A 472
 None
 1.07A 3fi0M-3sucA:
undetectable		 3fi0M-3sucA:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_N_TRPN1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3suc PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		5 / 9 GLY A 469
GLN A 437
ILE A 489
VAL A 496
VAL A 472
 None
 1.07A 3fi0N-3sucA:
undetectable		 3fi0N-3sucA:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_O_TRPO1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3suc PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		5 / 9 GLY A 469
GLN A 437
ILE A 489
VAL A 496
VAL A 472
 None
 1.03A 3fi0O-3sucA:
undetectable		 3fi0O-3sucA:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_R_TRPR1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3suc PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		5 / 9 GLY A 469
GLN A 437
ILE A 489
VAL A 496
VAL A 472
 None
 1.18A 3fi0R-3sucA:
undetectable		 3fi0R-3sucA:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GYQ_A_SAMA270_0
(RRNA
(ADENOSINE-2'-O-)-ME
THYLTRANSFERASE)		 3suc PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		5 / 12 LEU A 587
GLY A 603
ILE A 570
SER A 592
SER A 573
 None
 1.25A 3gyqA-3sucA:
undetectable
3gyqB-3sucA:
undetectable		 3gyqA-3sucA:
17.92
3gyqB-3sucA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPB_A_SAMA1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 3suc PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		5 / 12 ASN A 266
ILE A 244
THR A 284
ILE A 242
ILE A 269
 None
 1.21A 3kpbA-3sucA:
undetectable		 3kpbA-3sucA:
8.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LOQ_A_ACTA279_0
(UNIVERSAL STRESS
PROTEIN)		 3suc PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		4 / 4 SER A 604
SER A 592
THR A 606
SER A 607
 None
 1.47A 3loqA-3sucA:
undetectable		 3loqA-3sucA:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		 3suc PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		4 / 8 ILE A 269
VAL A 318
THR A 284
ILE A 244
 None
 0.75A 3p4wC-3sucA:
undetectable		 3p4wC-3sucA:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWW_A_ROCA1001_2
(ENDOTHIAPEPSIN)		 3suc PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		4 / 8 GLY A 621
ILE A 646
ASP A 625
SER A 640
 None
 0.67A 3pwwA-3sucA:
undetectable		 3pwwA-3sucA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNI_A_SALA1344_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3suc PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		4 / 7 ARG A 537
THR A 534
VAL A 535
LEU A 514
 None
 0.88A 3uniA-3sucA:
undetectable		 3uniA-3sucA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNI_B_SALB1345_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3suc PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		4 / 8 ARG A 537
THR A 534
VAL A 535
LEU A 514
 None
 0.89A 3uniB-3sucA:
undetectable		 3uniB-3sucA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3N_A_MIYA2001_1
(TETX2 PROTEIN)		 3suc PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		5 / 11 PHE A 309
GLY A 308
SER A 297
GLY A 350
ASN A 294
 None
 1.44A 3v3nA-3sucA:
undetectable		 3v3nA-3sucA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3N_D_MIYD2001_1
(TETX2 PROTEIN)		 3suc PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		5 / 11 PHE A 309
GLY A 308
SER A 297
GLY A 350
ASN A 294
 None
 1.44A 3v3nD-3sucA:
undetectable		 3v3nD-3sucA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VW1_B_CVIB301_0
(PUTATIVE REGULATORY
PROTEIN)		 3suc PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		5 / 12 LEU A 149
ILE A 229
ILE A 128
LEU A 219
PHE A 195
 None
 1.39A 3vw1B-3sucA:
undetectable		 3vw1B-3sucA:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		 3suc PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		4 / 6 THR A 432
ASN A 458
GLY A 486
ILE A 474
 None
 0.97A 3w9tF-3sucA:
undetectable		 3w9tF-3sucA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZTV_A_ADNA1600_1
(NAD NUCLEOTIDASE)		 3suc PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		5 / 9 ASN A 307
GLY A 330
PHE A 397
SER A 325
GLY A 331
 CA  A   1 ( 4.7A)
None
None
None
None
 1.32A 3ztvA-3sucA:
undetectable		 3ztvA-3sucA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A3P_A_ACTA1223_0
(UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 15)		 3suc PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		4 / 5 ASP A 312
THR A 283
GLU A 333
LYS A 335
 MG  A 857 (-3.4A)
MG  A 857 ( 4.9A)
None
CA  A   1 ( 4.6A)
 1.16A 4a3pA-3sucA:
undetectable		 4a3pA-3sucA:
14.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_D_MIYD391_1
(TETX2 PROTEIN)		 3suc PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		5 / 11 PHE A 309
GLY A 308
SER A 297
GLY A 350
ASN A 294
 None
 1.43A 4a99D-3sucA:
undetectable		 4a99D-3sucA:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1478_0
(MJ0495-LIKE PROTEIN)		 3suc PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		4 / 7 ASP A 280
GLY A 276
THR A 275
PHE A 309
 CA  A   1 (-2.5A)
None
None
None
 1.06A 4ac9C-3sucA:
undetectable		 4ac9C-3sucA:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DTA_B_ADNB401_1
(APH(2'')-ID)		 3suc PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		4 / 8 ILE A 267
ILE A 242
LEU A 219
ILE A 229
 None
 0.91A 4dtaB-3sucA:
undetectable		 4dtaB-3sucA:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IV0_B_SAMB302_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 3suc PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		5 / 12 TYR A 360
GLY A 308
GLY A 330
ILE A 282
SER A 325
 None
 1.07A 4iv0B-3sucA:
undetectable		 4iv0B-3sucA:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOE_F_TR6F101_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B
E-SITE DNA2)		 3suc PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		4 / 6 ARG A 439
GLY A 469
ASP A 470
GLY A 465
 None
 0.97A 4koeA-3sucA:
undetectable
4koeB-3sucA:
undetectable
4koeC-3sucA:
undetectable		 4koeA-3sucA:
20.40
4koeB-3sucA:
20.40
4koeC-3sucA:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOE_F_TR6F101_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B
E-SITE DNA2)		 3suc PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		4 / 6 SER A 456
GLY A 531
ASP A 506
GLY A 503
 None
 0.77A 4koeA-3sucA:
undetectable
4koeB-3sucA:
undetectable
4koeC-3sucA:
undetectable		 4koeA-3sucA:
20.40
4koeB-3sucA:
20.40
4koeC-3sucA:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOE_H_TR6H101_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B
E-SITE DNA4)		 3suc PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		4 / 7 SER A 456
GLY A 531
ASP A 506
GLY A 503
 None
 0.84A 4koeA-3sucA:
undetectable
4koeB-3sucA:
undetectable
4koeD-3sucA:
undetectable		 4koeA-3sucA:
20.40
4koeB-3sucA:
20.40
4koeD-3sucA:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWZ_A_SAMA301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 3suc PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		5 / 12 TYR A 360
GLY A 308
GLY A 330
ILE A 282
SER A 325
 None
 1.08A 4mwzA-3sucA:
undetectable		 4mwzA-3sucA:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1X_A_017A101_2
(ASPARTYL PROTEASE)		 3suc PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		5 / 12 LEU A 192
ILE A 269
ILE A 282
GLY A 241
ILE A 229
 None
 0.81A 4q1xB-3sucA:
undetectable		 4q1xB-3sucA:
9.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1X_A_017A101_2
(ASPARTYL PROTEASE)		 3suc PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		5 / 12 LEU A 192
ILE A 269
ILE A 282
VAL A 227
ILE A 229
 None
 0.89A 4q1xB-3sucA:
undetectable		 4q1xB-3sucA:
9.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3suc PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		5 / 11 THR A 238
GLY A 212
GLY A 213
SER A 214
ASP A 243
 None
 1.02A 4qvwK-3sucA:
undetectable
4qvwL-3sucA:
undetectable		 4qvwK-3sucA:
15.15
4qvwL-3sucA:
15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3suc PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		5 / 11 THR A 238
GLY A 212
GLY A 213
SER A 214
ASP A 243
 None
 1.02A 4qvwY-3sucA:
undetectable
4qvwZ-3sucA:
undetectable		 4qvwY-3sucA:
15.15
4qvwZ-3sucA:
15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X61_A_SAMA701_0
(PROTEIN ARGININE
N-METHYLTRANSFERASE
5)		 3suc PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		5 / 12 LEU A 428
GLY A 452
LEU A 479
ASN A 455
ARG A 390
 None
 1.22A 4x61A-3sucA:
undetectable		 4x61A-3sucA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XT7_A_TOPA302_1
(RV2671)		 3suc PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		5 / 11 ILE A 570
THR A 588
SER A 573
GLY A 572
PHE A 569
 None
 1.39A 4xt7A-3sucA:
undetectable		 4xt7A-3sucA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z53_F_TR6F101_1
(DNA TOPOISOMERASE 4
SUBUNIT B,DNA
TOPOISOMERASE 4
SUBUNIT A
E-SITE DNA)		 3suc PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		4 / 6 GLY A 469
ASP A 470
GLY A 465
ARG A 439
 None
 0.94A 4z53A-3sucA:
undetectable
4z53B-3sucA:
undetectable		 4z53A-3sucA:
20.36
4z53B-3sucA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z53_F_TR6F101_1
(DNA TOPOISOMERASE 4
SUBUNIT B,DNA
TOPOISOMERASE 4
SUBUNIT A
E-SITE DNA)		 3suc PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		4 / 6 GLY A 531
ASP A 506
GLY A 503
SER A 456
 None
 0.80A 4z53A-3sucA:
undetectable
4z53B-3sucA:
undetectable		 4z53A-3sucA:
20.36
4z53B-3sucA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z53_H_TR6H101_1
(DNA TOPOISOMERASE 4
SUBUNIT B,DNA
TOPOISOMERASE 4
SUBUNIT A
E-SITE DNA)		 3suc PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		4 / 7 GLY A 531
ASP A 506
GLY A 503
SER A 456
 None
 0.85A 4z53A-3sucA:
undetectable
4z53B-3sucA:
undetectable		 4z53A-3sucA:
20.36
4z53B-3sucA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0Y_A_FOLA201_0
(CONSERVED
HYPOTHETICAL
MEMBRANE PROTEIN)		 3suc PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		5 / 12 GLY A 186
ASP A 243
SER A 217
THR A 283
HIS A 225
 None
None
None
MG  A 857 ( 4.9A)
None
 1.46A 5d0yA-3sucA:
undetectable		 5d0yA-3sucA:
12.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_D_SAMD301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 3suc PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		5 / 12 GLY A 503
ILE A 501
LEU A 527
GLY A 486
GLY A 452
 None
 0.98A 5d4uD-3sucA:
undetectable		 5d4uD-3sucA:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JCN_B_ASCB502_0
(OS09G0567300 PROTEIN)		 3suc PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		4 / 6 GLU A 216
GLY A 210
ARG A 173
ARG A 301
 None
 1.43A 5jcnB-3sucA:
undetectable		 5jcnB-3sucA:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KM9_B_ADNB201_1
(HISTIDINE TRIAD
NUCLEOTIDE-BINDING
PROTEIN 2,
MITOCHONDRIAL)		 3suc PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		5 / 12 PHE A 124
ILE A 147
LEU A 149
SER A 106
VAL A 107
 None
 1.15A 5km9B-3sucA:
undetectable		 5km9B-3sucA:
10.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TWJ_A_SAMA201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)		 3suc PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		5 / 12 ILE A 348
GLY A 350
SER A 359
THR A 420
LEU A 419
 None
 1.02A 5twjA-3sucA:
undetectable		 5twjA-3sucA:
11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VW9_A_NCAA403_0
(FERREDOXIN--NADP
REDUCTASE)		 3suc PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		5 / 8 GLY A 486
ALA A 513
GLY A 459
GLU A 457
SER A 456
 None
 1.41A 5vw9A-3sucA:
undetectable		 5vw9A-3sucA:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A5Y_D_9CRD501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3suc PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		5 / 12 ILE A 818
ALA A 820
LEU A 710
ALA A 721
ILE A 832
 None
 0.93A 6a5yD-3sucA:
undetectable		 6a5yD-3sucA:
7.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_G_ZOLG401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 3suc PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		4 / 7 ASP A 280
ASP A 279
LYS A 335
TYR A 329
 CA  A   1 (-2.5A)
CA  A   1 (-2.9A)
CA  A   1 ( 4.6A)
None
 1.44A 6g31G-3sucA:
undetectable		 6g31G-3sucA:
8.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HLO_A_GBQA1501_1
(SUBSTANCE-P
RECEPTOR,GLGA
GLYCOGEN
SYNTHASE,SUBSTANCE-P
RECEPTOR)		 3suc PRENECK APPENDAGE
PROTEIN
(Bacillus
virus
phi29) 		5 / 9 ILE A 221
ILE A 242
GLU A 265
VAL A 227
ILE A 229
 None
 1.21A 6hloA-3sucA:
undetectable		 6hloA-3sucA:
19.48