SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3sv0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT2_A_SAMA301_1
(FIBRILLARIN-LIKE
PRE-RRNA PROCESSING
PROTEIN)		 3sv0 CASEIN KINASE I-LIKE
(Oryza
sativa) 		3 / 3 THR A  63
GLU A 117
ASP A 265
 None
 0.83A 1nt2A-3sv0A:
undetectable		 1nt2A-3sv0A:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SKX_A_RFPA1_2
(ORPHAN NUCLEAR
RECEPTOR PXR)		 3sv0 CASEIN KINASE I-LIKE
(Oryza
sativa) 		4 / 5 LYS A 122
PHE A 134
LEU A  59
LEU A 269
 None
 1.39A 1skxA-3sv0A:
undetectable		 1skxA-3sv0A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRE_B_CHDB701_0
(FERROCHELATASE)		 3sv0 CASEIN KINASE I-LIKE
(Oryza
sativa) 		3 / 3 LYS A  38
GLY A  86
PRO A  87
 None
 0.95A 2hreB-3sv0A:
undetectable		 2hreB-3sv0A:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BWY_A_SAMA301_0
(COMT PROTEIN)		 3sv0 CASEIN KINASE I-LIKE
(Oryza
sativa) 		5 / 12 MET A 112
VAL A 116
GLY A 200
GLN A 214
ARG A 178
 None
 1.45A 3bwyA-3sv0A:
undetectable		 3bwyA-3sv0A:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_A_AERA601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3sv0 CASEIN KINASE I-LIKE
(Oryza
sativa) 		5 / 12 ASN A 133
ILE A 148
ILE A 147
ALA A 153
VAL A 119
 None
 0.99A 4nkvA-3sv0A:
undetectable		 4nkvA-3sv0A:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_B_AERB601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3sv0 CASEIN KINASE I-LIKE
(Oryza
sativa) 		5 / 12 ASN A 133
ILE A 148
ILE A 147
ALA A 153
VAL A 119
 None
 0.99A 4nkvB-3sv0A:
undetectable		 4nkvB-3sv0A:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_D_AERD601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3sv0 CASEIN KINASE I-LIKE
(Oryza
sativa) 		5 / 12 ASN A 133
ILE A 148
ILE A 147
ALA A 153
VAL A 119
 None
 1.02A 4nkvD-3sv0A:
undetectable		 4nkvD-3sv0A:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XOY_A_DX4A401_0
(MITOGEN-ACTIVATED
PROTEIN KINASE 1)		 3sv0 CASEIN KINASE I-LIKE
(Oryza
sativa) 		4 / 6 ALA A  36
LYS A  38
LEU A  84
LEU A 135
 None
 0.74A 4xoyA-3sv0A:
17.8		 4xoyA-3sv0A:
23.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP3_A_DX4A401_0
(MITOGEN-ACTIVATED
PROTEIN KINASE 1)		 3sv0 CASEIN KINASE I-LIKE
(Oryza
sativa) 		4 / 6 ALA A  36
LYS A  38
LEU A  84
LEU A 135
 None
 0.89A 4xp3A-3sv0A:
18.1		 4xp3A-3sv0A:
23.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IZJ_F_AZ1F2_1
(CAMP-DEPENDENT
PROTEIN KINASE
CATALYTIC SUBUNIT
ALPHA
47P-AZ1-DAR-DAR-DAR)		 3sv0 CASEIN KINASE I-LIKE
(Oryza
sativa) 		4 / 7 GLY A  16
GLY A  18
SER A  19
GLY A  21
 None
 0.37A 5izjB-3sv0A:
18.8		 5izjB-3sv0A:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LSA_A_SAMA303_0
(CATECHOL
O-METHYLTRANSFERASE)		 3sv0 CASEIN KINASE I-LIKE
(Oryza
sativa) 		5 / 12 MET A 112
VAL A 116
GLY A 200
GLN A 214
ARG A 178
 None
 1.41A 5lsaA-3sv0A:
undetectable		 5lsaA-3sv0A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2O_A_8N6A501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3sv0 CASEIN KINASE I-LIKE
(Oryza
sativa) 		5 / 12 TYR A 266
LEU A 269
HIS A 120
LEU A 125
TYR A 156
 None
 1.43A 5y2oA-3sv0A:
undetectable		 5y2oA-3sv0A:
9.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_A_8LXA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3sv0 CASEIN KINASE I-LIKE
(Oryza
sativa) 		5 / 12 LEU A 211
TYR A 266
LEU A 269
HIS A 120
LEU A 125
 None
 1.23A 5y2tA-3sv0A:
undetectable		 5y2tA-3sv0A:
undetectable