SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3svi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UDT_A_VIAA1000_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 3svi TYPE III EFFECTOR
HOPAB2
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 12 ALA A 211
ALA A 158
LEU A 178
MET A 166
PHE A 167
 None
 1.14A 1udtA-3sviA:
undetectable		 1udtA-3sviA:
14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G78_A_REAA200_1
(CELLULAR RETINOIC
ACID-BINDING PROTEIN
2)		 3svi TYPE III EFFECTOR
HOPAB2
(Pseudomonas
syringae
group
genomosp.
3) 		6 / 12 PHE A 167
LEU A 171
ILE A 206
ALA A 205
LEU A 178
MET A 176
 None
 1.44A 2g78A-3sviA:
undetectable		 2g78A-3sviA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H42_B_VIAB902_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 3svi TYPE III EFFECTOR
HOPAB2
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 12 ALA A 211
ALA A 158
LEU A 178
MET A 166
PHE A 167
 None
 1.05A 2h42B-3sviA:
undetectable		 2h42B-3sviA:
14.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IYF_B_ERYB1399_0
(OLEANDOMYCIN
GLYCOSYLTRANSFERASE)		 3svi TYPE III EFFECTOR
HOPAB2
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 12 VAL A 185
PHE A 186
ASN A 162
SER A 179
ASP A 216
 None
 1.26A 2iyfB-3sviA:
undetectable		 2iyfB-3sviA:
14.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JN3_A_JN3A131_2
(FATTY ACID-BINDING
PROTEIN, LIVER)		 3svi TYPE III EFFECTOR
HOPAB2
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 6 LEU A 208
ASN A 184
ILE A 163
PHE A 167
 None
CL  A   3 (-3.5A)
None
None
 1.24A 2jn3A-3sviA:
undetectable		 2jn3A-3sviA:
16.54