SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3svl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOF_C_FRDC305_2
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 3svl PROTEIN YIEF
(Escherichia
coli) 		4 / 5 LEU A  27
PRO A  32
ALA A  31
ILE A  30
 None
 1.00A 2aofB-3svlA:
undetectable		 2aofB-3svlA:
23.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CD2_A_FOLA307_0
(DIHYDROFOLATE
REDUCTASE)		 3svl PROTEIN YIEF
(Escherichia
coli) 		5 / 12 ILE A 113
LEU A 137
ILE A 133
LEU A  91
ILE A  78
 None
 0.99A 2cd2A-3svlA:
undetectable		 2cd2A-3svlA:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KOC_B_SAMB401_0
(PAVINE
N-METHYLTRANSFERASE)		 3svl PROTEIN YIEF
(Escherichia
coli) 		5 / 12 GLY A 149
THR A 115
GLN A 127
VAL A  23
HIS A 171
 None
 1.11A 5kocB-3svlA:
undetectable		 5kocB-3svlA:
18.52