SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3sw0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1YAJ_K_BEZK4387_0 (CES1 PROTEIN)	3sw0	COMPLEMENT FACTOR H (Homo sapiens)	3 / 3	TRP X1183 LEU X1181 LYS X1188	None	1.48A	1yajK-3sw0X: undetectable	1yajK-3sw0X: 14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QD3_B_CHDB504_0 (FERROCHELATASE)	3sw0	COMPLEMENT FACTOR H (Homo sapiens)	4 / 6	MET X1090 ARG X1074 PRO X1051 MET X1064	None	1.39A	2qd3B-3sw0X: undetectable	2qd3B-3sw0X: 19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3HS4_A_AZMA702_1 (CARBONIC ANHYDRASE 2)	3sw0	COMPLEMENT FACTOR H (Homo sapiens)	4 / 7	VAL X1134 TYR X1136 GLU X1159 PRO X1160	None	1.26A	3hs4A-3sw0X: undetectable	3hs4A-3sw0X: 19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OYA_A_RLTA398_1 (PFV INTEGRASE)	3sw0	COMPLEMENT FACTOR H (Homo sapiens)	4 / 8	ASP X1220 PRO X1166 TYR X1142 GLU X1145	None	1.02A	3oyaA-3sw0X: undetectable	3oyaA-3sw0X: 19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5D0Y_A_FOLA201_1 (CONSERVED HYPOTHETICAL MEMBRANE PROTEIN)	3sw0	COMPLEMENT FACTOR H (Homo sapiens)	3 / 3	ARG X1149 LYS X1148 GLU X1135	None	0.79A	5d0yA-3sw0X: undetectable	5d0yA-3sw0X: 21.96

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1YAJ_K_BEZK4387_0","CES1 PROTEIN","3sw0","COMPLEMENT FACTOR H","Homo sapiens",3,"TRP X1183;LEU X1181;LYS X1188","None","1.48A","1yajK-3sw0X:undetectable","1yajK-3sw0X:14.77"],["2QD3_B_CHDB504_0","FERROCHELATASE","3sw0","COMPLEMENT FACTOR H","Homo sapiens",4,"MET X1090;ARG X1074;PRO X1051;MET X1064","None","1.39A","2qd3B-3sw0X:undetectable","2qd3B-3sw0X:19.61"],["3HS4_A_AZMA702_1","CARBONIC ANHYDRASE 2","3sw0","COMPLEMENT FACTOR H","Homo sapiens",4,"VAL X1134;TYR X1136;GLU X1159;PRO X1160","None","1.26A","3hs4A-3sw0X:undetectable","3hs4A-3sw0X:19.78"],["3OYA_A_RLTA398_1","PFV INTEGRASE","3sw0","COMPLEMENT FACTOR H","Homo sapiens",4,"ASP X1220;PRO X1166;TYR X1142;GLU X1145","None","1.02A","3oyaA-3sw0X:undetectable","3oyaA-3sw0X:19.24"],["5D0Y_A_FOLA201_1","CONSERVED HYPOTHETICAL MEMBRANE PROTEIN","3sw0","COMPLEMENT FACTOR H","Homo sapiens",3,"ARG X1149;LYS X1148;GLU X1135","None","0.79A","5d0yA-3sw0X:undetectable","5d0yA-3sw0X:21.96"]]