SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3syb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_A_CCSA381_0
(ESTROGEN RECEPTOR)		 3syb GLYCINE-GLUTAMATE
DIPEPTIDE PORIN OPDP
(Pseudomonas
aeruginosa) 		4 / 5 HIS A 328
GLU A 216
ALA A 332
SER A 168
 None
 0.99A 1errA-3sybA:
undetectable
1errB-3sybA:
undetectable		 1errA-3sybA:
19.57
1errB-3sybA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RMT_B_ADNB1502_1
(CLASS B ACID
PHOSPHATASE)		 3syb GLYCINE-GLUTAMATE
DIPEPTIDE PORIN OPDP
(Pseudomonas
aeruginosa) 		4 / 7 PHE A 100
LEU A 148
THR A  94
TYR A  93
 None
None
SO4  A 468 (-4.2A)
SO4  A 469 (-4.8A)
 1.26A 1rmtB-3sybA:
undetectable		 1rmtB-3sybA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZLQ_A_ACTA1502_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 3syb GLYCINE-GLUTAMATE
DIPEPTIDE PORIN OPDP
(Pseudomonas
aeruginosa) 		4 / 5 PRO A 165
GLY A 279
ASN A 278
GLY A 259
 None
C8E  A 471 (-4.1A)
None
None
 1.00A 1zlqA-3sybA:
undetectable		 1zlqA-3sybA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DR6_A_DM2A2002_1
(ACRB)		 3syb GLYCINE-GLUTAMATE
DIPEPTIDE PORIN OPDP
(Pseudomonas
aeruginosa) 		5 / 9 SER A 350
GLN A 316
GLY A 443
ILE A 441
PHE A 324
 None
 1.49A 2dr6A-3sybA:
0.0		 2dr6A-3sybA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HMA_A_SAMA375_0
(PROBABLE TRNA
(5-METHYLAMINOMETHYL
-2-THIOURIDYLATE)-ME
THYLTRANSFERASE)		 3syb GLYCINE-GLUTAMATE
DIPEPTIDE PORIN OPDP
(Pseudomonas
aeruginosa) 		5 / 11 GLY A  41
SER A  91
THR A  36
GLY A  37
GLN A  32
 None
None
SO4  A 469 ( 4.7A)
SO4  A 468 ( 3.8A)
None
 1.10A 2hmaA-3sybA:
undetectable		 2hmaA-3sybA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DL9_B_V2HB602_0
(CYTOCHROME P450 2R1)		 3syb GLYCINE-GLUTAMATE
DIPEPTIDE PORIN OPDP
(Pseudomonas
aeruginosa) 		5 / 12 VAL A  86
ALA A 105
THR A 453
ILE A  22
THR A  47
 None
 1.27A 3dl9B-3sybA:
undetectable		 3dl9B-3sybA:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MB5_A_SAMA301_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3syb GLYCINE-GLUTAMATE
DIPEPTIDE PORIN OPDP
(Pseudomonas
aeruginosa) 		4 / 4 GLY A 320
GLU A 322
ASP A 385
ASP A 296
 None
None
None
C8E  A 471 ( 4.8A)
 1.40A 3mb5A-3sybA:
undetectable		 3mb5A-3sybA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MB5_A_SAMA301_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3syb GLYCINE-GLUTAMATE
DIPEPTIDE PORIN OPDP
(Pseudomonas
aeruginosa) 		4 / 4 GLY A 320
GLU A 322
ASP A 385
ASP A 319
 None
 1.16A 3mb5A-3sybA:
undetectable		 3mb5A-3sybA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QXY_B_SAMB6735_0
(N-LYSINE
METHYLTRANSFERASE
SETD6
TRANSCRIPTION FACTOR
P65)		 3syb GLYCINE-GLUTAMATE
DIPEPTIDE PORIN OPDP
(Pseudomonas
aeruginosa) 		5 / 11 VAL A 252
ALA A 290
TYR A 292
TYR A 384
TYR A 323
 None
 1.50A 3qxyB-3sybA:
undetectable
3qxyQ-3sybA:
undetectable		 3qxyB-3sybA:
21.12
3qxyQ-3sybA:
5.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3XIM_B_SORB397_0
(D-XYLOSE ISOMERASE)		 3syb GLYCINE-GLUTAMATE
DIPEPTIDE PORIN OPDP
(Pseudomonas
aeruginosa) 		5 / 12 THR A 297
VAL A 318
GLU A 348
HIS A 406
ASP A 442
 None
 1.40A 3ximB-3sybA:
undetectable		 3ximB-3sybA:
23.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3XIM_C_SORC397_0
(D-XYLOSE ISOMERASE)		 3syb GLYCINE-GLUTAMATE
DIPEPTIDE PORIN OPDP
(Pseudomonas
aeruginosa) 		5 / 12 THR A 297
VAL A 318
GLU A 348
HIS A 406
ASP A 442
 None
 1.45A 3ximC-3sybA:
undetectable		 3ximC-3sybA:
23.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3XIM_D_SORD397_0
(D-XYLOSE ISOMERASE)		 3syb GLYCINE-GLUTAMATE
DIPEPTIDE PORIN OPDP
(Pseudomonas
aeruginosa) 		5 / 12 THR A 297
VAL A 318
GLU A 348
HIS A 406
ASP A 442
 None
 1.45A 3ximD-3sybA:
undetectable		 3ximD-3sybA:
23.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AT0_A_ACTA1490_0
(3-KETOSTEROID-DELTA4
-5ALPHA-DEHYDROGENAS
E)		 3syb GLYCINE-GLUTAMATE
DIPEPTIDE PORIN OPDP
(Pseudomonas
aeruginosa) 		3 / 3 GLU A 216
TYR A 326
SER A 331
 None
 0.87A 4at0A-3sybA:
undetectable		 4at0A-3sybA:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_D_HCYD1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 3syb GLYCINE-GLUTAMATE
DIPEPTIDE PORIN OPDP
(Pseudomonas
aeruginosa) 		5 / 12 SER A 203
GLN A 195
THR A 164
ARG A 159
PHE A 167
 None
 1.29A 4c49D-3sybA:
undetectable		 4c49D-3sybA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MV7_A_PPFA501_1
(BIOTIN CARBOXYLASE)		 3syb GLYCINE-GLUTAMATE
DIPEPTIDE PORIN OPDP
(Pseudomonas
aeruginosa) 		4 / 7 ASN A 172
ARG A 205
GLU A 216
ARG A 220
 None
 0.95A 4mv7A-3sybA:
undetectable		 4mv7A-3sybA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NTX_A_AMRA509_1
(ACID-SENSING ION
CHANNEL 1
BASIC PHOSPHOLIPASE
A2 HOMOLOG TX-BETA)		 3syb GLYCINE-GLUTAMATE
DIPEPTIDE PORIN OPDP
(Pseudomonas
aeruginosa) 		4 / 6 GLU A 408
GLU A 216
ASN A 172
ARG A 173
 None
 1.19A 4ntxA-3sybA:
undetectable
4ntxC-3sybA:
undetectable		 4ntxA-3sybA:
21.72
4ntxC-3sybA:
11.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUE_A_SAMA303_1
(CATECHOL
O-METHYLTRANSFERASE)		 3syb GLYCINE-GLUTAMATE
DIPEPTIDE PORIN OPDP
(Pseudomonas
aeruginosa) 		4 / 5 GLY A 320
TYR A 280
GLU A 322
ASP A 296
 None
None
None
C8E  A 471 ( 4.8A)
 1.36A 4xueA-3sybA:
undetectable		 4xueA-3sybA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AOX_C_ACTC1001_0
(ALU JO CONSENSUS RNA
SIGNAL RECOGNITION
PARTICLE 14 KDA
PROTEIN)		 3syb GLYCINE-GLUTAMATE
DIPEPTIDE PORIN OPDP
(Pseudomonas
aeruginosa) 		3 / 3 TYR A 280
THR A 282
THR A 297
 None
 0.53A 5aoxB-3sybA:
undetectable		 5aoxB-3sybA:
10.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AOX_F_ACTF1001_0
(ALU JO CONSENSUS RNA
SIGNAL RECOGNITION
PARTICLE 14 KDA
PROTEIN)		 3syb GLYCINE-GLUTAMATE
DIPEPTIDE PORIN OPDP
(Pseudomonas
aeruginosa) 		3 / 3 TYR A 280
THR A 282
THR A 297
 None
 0.46A 5aoxE-3sybA:
undetectable		 5aoxE-3sybA:
10.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EAJ_B_FOLB201_1
(DIHYDROFOLATE
REDUCTASE)		 3syb GLYCINE-GLUTAMATE
DIPEPTIDE PORIN OPDP
(Pseudomonas
aeruginosa) 		3 / 3 ASP A 442
ARG A 205
ARG A 220
 None
 0.96A 5eajB-3sybA:
undetectable		 5eajB-3sybA:
15.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIM_A_SORA397_0
(D-XYLOSE ISOMERASE)		 3syb GLYCINE-GLUTAMATE
DIPEPTIDE PORIN OPDP
(Pseudomonas
aeruginosa) 		5 / 12 THR A 297
VAL A 318
GLU A 348
HIS A 406
ASP A 442
 None
 1.50A 5ximA-3sybA:
undetectable		 5ximA-3sybA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIM_D_SORD397_0
(D-XYLOSE ISOMERASE)		 3syb GLYCINE-GLUTAMATE
DIPEPTIDE PORIN OPDP
(Pseudomonas
aeruginosa) 		5 / 12 THR A 297
VAL A 318
GLU A 348
HIS A 406
ASP A 442
 None
 1.49A 5ximD-3sybA:
undetectable		 5ximD-3sybA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_A_EY4A502_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 3syb GLYCINE-GLUTAMATE
DIPEPTIDE PORIN OPDP
(Pseudomonas
aeruginosa) 		4 / 7 ALA A  80
GLN A  83
VAL A  82
TRP A  81
 None
C8E  A 472 ( 3.6A)
None
None
 0.94A 6cduA-3sybA:
undetectable
6cduE-3sybA:
undetectable		 6cduA-3sybA:
21.35
6cduE-3sybA:
21.35