SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3syq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		 3syq G PROTEIN-ACTIVATED
INWARD RECTIFIER
POTASSIUM CHANNEL 2
(Mus
musculus) 		4 / 7 ILE A 262
ILE A 213
ILE A 294
LEU A 220
 None
 0.76A 5fukA-3syqA:
undetectable
5fukB-3syqA:
undetectable		 5fukA-3syqA:
21.84
5fukB-3syqA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OSP_A_ACTA403_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 3syq G PROTEIN-ACTIVATED
INWARD RECTIFIER
POTASSIUM CHANNEL 2
(Mus
musculus) 		4 / 7 VAL A 264
ILE A 262
VAL A 308
ALA A 241
 None
 0.76A 5ospA-3syqA:
undetectable		 5ospA-3syqA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OSR_A_ACTA402_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 3syq G PROTEIN-ACTIVATED
INWARD RECTIFIER
POTASSIUM CHANNEL 2
(Mus
musculus) 		4 / 7 VAL A 264
ILE A 262
VAL A 308
ALA A 241
 None
 0.77A 5osrA-3syqA:
undetectable		 5osrA-3syqA:
20.15