SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3sz3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FK6_A_LNLA1201_1
(NON-SPECIFIC LIPID
TRANSFER PROTEIN)		 3sz3 TRYPTOPHANYL-TRNA
SYNTHETASE
(Vibrio
cholerae) 		5 / 12 VAL A  94
LEU A  95
ASN A  96
ALA A 133
ALA A 321
 None
 0.97A 1fk6A-3sz3A:
undetectable		 1fk6A-3sz3A:
12.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JNO_A_DVAA6_0
(GRAMICIDIN A)		 3sz3 TRYPTOPHANYL-TRNA
SYNTHETASE
(Vibrio
cholerae) 		3 / 3 ALA A  69
VAL A  72
TRP A  28
 None
 0.79A 1jnoA-3sz3A:
undetectable		 1jnoA-3sz3A:
7.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JNO_B_DVAB6_0
(GRAMICIDIN A)		 3sz3 TRYPTOPHANYL-TRNA
SYNTHETASE
(Vibrio
cholerae) 		3 / 3 ALA A  69
VAL A  72
TRP A  28
 None
 0.79A 1jnoB-3sz3A:
undetectable		 1jnoB-3sz3A:
7.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO3_A_DVAA6_0
(GRAMICIDIN B)		 3sz3 TRYPTOPHANYL-TRNA
SYNTHETASE
(Vibrio
cholerae) 		3 / 3 ALA A  69
VAL A  72
TRP A  28
 None
 0.82A 1jo3A-3sz3A:
undetectable		 1jo3A-3sz3A:
7.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO3_B_DVAB6_0
(GRAMICIDIN B)		 3sz3 TRYPTOPHANYL-TRNA
SYNTHETASE
(Vibrio
cholerae) 		3 / 3 ALA A  69
VAL A  72
TRP A  28
 None
 0.82A 1jo3B-3sz3A:
undetectable		 1jo3B-3sz3A:
7.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO4_A_DVAA6_0
(GRAMICIDIN C)		 3sz3 TRYPTOPHANYL-TRNA
SYNTHETASE
(Vibrio
cholerae) 		3 / 3 ALA A  69
VAL A  72
TRP A  28
 None
 0.81A 1jo4A-3sz3A:
undetectable		 1jo4A-3sz3A:
7.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO4_B_DVAB6_0
(GRAMICIDIN C)		 3sz3 TRYPTOPHANYL-TRNA
SYNTHETASE
(Vibrio
cholerae) 		3 / 3 ALA A  69
VAL A  72
TRP A  28
 None
 0.81A 1jo4B-3sz3A:
undetectable		 1jo4B-3sz3A:
7.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAG_A_DVAA6_0
(GRAMICIDIN A)		 3sz3 TRYPTOPHANYL-TRNA
SYNTHETASE
(Vibrio
cholerae) 		3 / 3 ALA A  69
VAL A  72
TRP A  28
 None
 0.77A 1magA-3sz3A:
undetectable		 1magA-3sz3A:
7.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAG_B_DVAB6_0
(GRAMICIDIN A)		 3sz3 TRYPTOPHANYL-TRNA
SYNTHETASE
(Vibrio
cholerae) 		3 / 3 ALA A  69
VAL A  72
TRP A  28
 None
 0.77A 1magB-3sz3A:
undetectable		 1magB-3sz3A:
7.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NG8_A_DVAA6_0
(GRAMICIDIN A)		 3sz3 TRYPTOPHANYL-TRNA
SYNTHETASE
(Vibrio
cholerae) 		3 / 3 ALA A  69
VAL A  72
TRP A  28
 None
 0.81A 1ng8A-3sz3A:
undetectable		 1ng8A-3sz3A:
4.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NG8_B_DVAB6_0
(GRAMICIDIN A)		 3sz3 TRYPTOPHANYL-TRNA
SYNTHETASE
(Vibrio
cholerae) 		3 / 3 ALA A  69
VAL A  72
TRP A  28
 None
 0.81A 1ng8B-3sz3A:
undetectable		 1ng8B-3sz3A:
4.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRM_A_DVAA6_0
(GRAMICIDIN A)		 3sz3 TRYPTOPHANYL-TRNA
SYNTHETASE
(Vibrio
cholerae) 		3 / 3 ALA A  69
VAL A  72
TRP A  28
 None
 0.76A 1nrmA-3sz3A:
undetectable		 1nrmA-3sz3A:
7.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRM_B_DVAB6_0
(GRAMICIDIN A)		 3sz3 TRYPTOPHANYL-TRNA
SYNTHETASE
(Vibrio
cholerae) 		3 / 3 ALA A  69
VAL A  72
TRP A  28
 None
 0.75A 1nrmB-3sz3A:
undetectable		 1nrmB-3sz3A:
7.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRU_A_DVAA6_0
(GRAMICIDIN A)		 3sz3 TRYPTOPHANYL-TRNA
SYNTHETASE
(Vibrio
cholerae) 		3 / 3 ALA A  69
VAL A  72
TRP A  28
 None
 0.83A 1nruA-3sz3A:
undetectable		 1nruA-3sz3A:
7.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRU_B_DVAB6_0
(GRAMICIDIN A)		 3sz3 TRYPTOPHANYL-TRNA
SYNTHETASE
(Vibrio
cholerae) 		3 / 3 ALA A  69
VAL A  72
TRP A  28
 None
 0.83A 1nruB-3sz3A:
undetectable		 1nruB-3sz3A:
7.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT6_A_DVAA6_0
(GRAMICIDIN C)		 3sz3 TRYPTOPHANYL-TRNA
SYNTHETASE
(Vibrio
cholerae) 		3 / 3 ALA A  69
VAL A  72
TRP A  28
 None
 0.63A 1nt6A-3sz3A:
undetectable		 1nt6A-3sz3A:
6.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT6_B_DVAB6_0
(GRAMICIDIN C)		 3sz3 TRYPTOPHANYL-TRNA
SYNTHETASE
(Vibrio
cholerae) 		3 / 3 ALA A  69
VAL A  72
TRP A  28
 None
 0.63A 1nt6B-3sz3A:
undetectable		 1nt6B-3sz3A:
6.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_B_DVAB6_0
(GRAMICIDIN D)		 3sz3 TRYPTOPHANYL-TRNA
SYNTHETASE
(Vibrio
cholerae) 		3 / 3 TRP A  28
ALA A  69
VAL A  72
 None
 0.72A 2izqA-3sz3A:
undetectable
2izqB-3sz3A:
undetectable		 2izqA-3sz3A:
7.19
2izqB-3sz3A:
7.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OPX_A_DXCA1003_0
(ALDEHYDE
DEHYDROGENASE A)		 3sz3 TRYPTOPHANYL-TRNA
SYNTHETASE
(Vibrio
cholerae) 		4 / 5 ILE A 160
LEU A  95
ASP A 135
ALA A 157
 None
None
TRP  A 401 (-4.0A)
None
 1.04A 2opxA-3sz3A:
undetectable		 2opxA-3sz3A:
25.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FHJ_A_TRPA1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3sz3 TRYPTOPHANYL-TRNA
SYNTHETASE
(Vibrio
cholerae) 		6 / 10 GLN A  11
VAL A  42
MET A 132
ASP A 135
ILE A 136
VAL A 146
 TRP  A 401 (-3.2A)
TRP  A 401 (-4.7A)
TRP  A 401 (-4.0A)
TRP  A 401 (-4.0A)
None
None
 0.91A 3fhjA-3sz3A:
38.3		 3fhjA-3sz3A:
52.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FHJ_A_TRPA1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3sz3 TRYPTOPHANYL-TRNA
SYNTHETASE
(Vibrio
cholerae) 		7 / 10 GLY A   9
VAL A  42
MET A 132
ASP A 135
ILE A 136
VAL A 144
VAL A 146
 TRP  A 401 (-3.8A)
TRP  A 401 (-4.7A)
TRP  A 401 (-4.0A)
TRP  A 401 (-4.0A)
None
TRP  A 401 (-4.9A)
None
 0.54A 3fhjA-3sz3A:
38.3		 3fhjA-3sz3A:
52.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FHJ_A_TRPA1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3sz3 TRYPTOPHANYL-TRNA
SYNTHETASE
(Vibrio
cholerae) 		7 / 10 VAL A  42
MET A 132
ASP A 135
ILE A 136
VAL A 144
VAL A 146
GLN A 150
 TRP  A 401 (-4.7A)
TRP  A 401 (-4.0A)
TRP  A 401 (-4.0A)
None
TRP  A 401 (-4.9A)
None
TRP  A 401 (-3.8A)
 1.04A 3fhjA-3sz3A:
38.3		 3fhjA-3sz3A:
52.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FHJ_B_TRPB1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3sz3 TRYPTOPHANYL-TRNA
SYNTHETASE
(Vibrio
cholerae) 		8 / 10 GLY A   9
GLN A  11
VAL A  42
MET A 132
ASP A 135
ILE A 136
VAL A 144
VAL A 146
 TRP  A 401 (-3.8A)
TRP  A 401 (-3.2A)
TRP  A 401 (-4.7A)
TRP  A 401 (-4.0A)
TRP  A 401 (-4.0A)
None
TRP  A 401 (-4.9A)
None
 0.79A 3fhjB-3sz3A:
36.8		 3fhjB-3sz3A:
52.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FHJ_B_TRPB1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3sz3 TRYPTOPHANYL-TRNA
SYNTHETASE
(Vibrio
cholerae) 		5 / 10 GLY A   9
GLN A  11
VAL A  42
MET A 132
VAL A 144
 TRP  A 401 (-3.8A)
TRP  A 401 (-3.2A)
TRP  A 401 (-4.7A)
TRP  A 401 (-4.0A)
TRP  A 401 (-4.9A)
 1.31A 3fhjB-3sz3A:
36.8		 3fhjB-3sz3A:
52.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FHJ_B_TRPB1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3sz3 TRYPTOPHANYL-TRNA
SYNTHETASE
(Vibrio
cholerae) 		7 / 10 VAL A  42
MET A 132
ASP A 135
ILE A 136
VAL A 144
VAL A 146
GLN A 150
 TRP  A 401 (-4.7A)
TRP  A 401 (-4.0A)
TRP  A 401 (-4.0A)
None
TRP  A 401 (-4.9A)
None
TRP  A 401 (-3.8A)
 1.04A 3fhjB-3sz3A:
36.8		 3fhjB-3sz3A:
52.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FHJ_C_TRPC1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3sz3 TRYPTOPHANYL-TRNA
SYNTHETASE
(Vibrio
cholerae) 		8 / 10 GLY A   9
GLN A  11
VAL A  42
MET A 132
ASP A 135
ILE A 136
VAL A 144
VAL A 146
 TRP  A 401 (-3.8A)
TRP  A 401 (-3.2A)
TRP  A 401 (-4.7A)
TRP  A 401 (-4.0A)
TRP  A 401 (-4.0A)
None
TRP  A 401 (-4.9A)
None
 0.79A 3fhjC-3sz3A:
35.7		 3fhjC-3sz3A:
52.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FHJ_C_TRPC1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3sz3 TRYPTOPHANYL-TRNA
SYNTHETASE
(Vibrio
cholerae) 		5 / 10 GLY A   9
GLN A  11
VAL A  42
MET A 132
VAL A 144
 TRP  A 401 (-3.8A)
TRP  A 401 (-3.2A)
TRP  A 401 (-4.7A)
TRP  A 401 (-4.0A)
TRP  A 401 (-4.9A)
 1.34A 3fhjC-3sz3A:
35.7		 3fhjC-3sz3A:
52.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FHJ_C_TRPC1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3sz3 TRYPTOPHANYL-TRNA
SYNTHETASE
(Vibrio
cholerae) 		7 / 10 VAL A  42
MET A 132
ASP A 135
ILE A 136
VAL A 144
VAL A 146
GLN A 150
 TRP  A 401 (-4.7A)
TRP  A 401 (-4.0A)
TRP  A 401 (-4.0A)
None
TRP  A 401 (-4.9A)
None
TRP  A 401 (-3.8A)
 1.04A 3fhjC-3sz3A:
35.7		 3fhjC-3sz3A:
52.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FHJ_D_TRPD1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3sz3 TRYPTOPHANYL-TRNA
SYNTHETASE
(Vibrio
cholerae) 		7 / 9 GLY A   9
VAL A  42
MET A 132
ASP A 135
ILE A 136
VAL A 144
VAL A 146
 TRP  A 401 (-3.8A)
TRP  A 401 (-4.7A)
TRP  A 401 (-4.0A)
TRP  A 401 (-4.0A)
None
TRP  A 401 (-4.9A)
None
 0.55A 3fhjD-3sz3A:
37.3		 3fhjD-3sz3A:
52.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FHJ_D_TRPD1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3sz3 TRYPTOPHANYL-TRNA
SYNTHETASE
(Vibrio
cholerae) 		7 / 9 VAL A  42
MET A 132
ASP A 135
ILE A 136
VAL A 144
VAL A 146
GLN A 150
 TRP  A 401 (-4.7A)
TRP  A 401 (-4.0A)
TRP  A 401 (-4.0A)
None
TRP  A 401 (-4.9A)
None
TRP  A 401 (-3.8A)
 1.04A 3fhjD-3sz3A:
37.3		 3fhjD-3sz3A:
52.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FHJ_E_TRPE1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3sz3 TRYPTOPHANYL-TRNA
SYNTHETASE
(Vibrio
cholerae) 		6 / 10 GLN A  11
VAL A  42
MET A 132
ASP A 135
ILE A 136
VAL A 146
 TRP  A 401 (-3.2A)
TRP  A 401 (-4.7A)
TRP  A 401 (-4.0A)
TRP  A 401 (-4.0A)
None
None
 0.84A 3fhjE-3sz3A:
37.6		 3fhjE-3sz3A:
52.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FHJ_E_TRPE1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3sz3 TRYPTOPHANYL-TRNA
SYNTHETASE
(Vibrio
cholerae) 		7 / 10 GLY A   9
VAL A  42
MET A 132
ASP A 135
ILE A 136
VAL A 144
VAL A 146
 TRP  A 401 (-3.8A)
TRP  A 401 (-4.7A)
TRP  A 401 (-4.0A)
TRP  A 401 (-4.0A)
None
TRP  A 401 (-4.9A)
None
 0.54A 3fhjE-3sz3A:
37.6		 3fhjE-3sz3A:
52.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FHJ_E_TRPE1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3sz3 TRYPTOPHANYL-TRNA
SYNTHETASE
(Vibrio
cholerae) 		7 / 10 VAL A  42
MET A 132
ASP A 135
ILE A 136
VAL A 144
VAL A 146
GLN A 150
 TRP  A 401 (-4.7A)
TRP  A 401 (-4.0A)
TRP  A 401 (-4.0A)
None
TRP  A 401 (-4.9A)
None
TRP  A 401 (-3.8A)
 1.04A 3fhjE-3sz3A:
37.6		 3fhjE-3sz3A:
52.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FHJ_F_TRPF1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3sz3 TRYPTOPHANYL-TRNA
SYNTHETASE
(Vibrio
cholerae) 		7 / 9 GLY A   9
VAL A  42
MET A 132
ASP A 135
ILE A 136
VAL A 144
VAL A 146
 TRP  A 401 (-3.8A)
TRP  A 401 (-4.7A)
TRP  A 401 (-4.0A)
TRP  A 401 (-4.0A)
None
TRP  A 401 (-4.9A)
None
 0.54A 3fhjF-3sz3A:
38.2		 3fhjF-3sz3A:
52.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FHJ_F_TRPF1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3sz3 TRYPTOPHANYL-TRNA
SYNTHETASE
(Vibrio
cholerae) 		7 / 9 VAL A  42
MET A 132
ASP A 135
ILE A 136
VAL A 144
VAL A 146
GLN A 150
 TRP  A 401 (-4.7A)
TRP  A 401 (-4.0A)
TRP  A 401 (-4.0A)
None
TRP  A 401 (-4.9A)
None
TRP  A 401 (-3.8A)
 1.04A 3fhjF-3sz3A:
38.2		 3fhjF-3sz3A:
52.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_A_TRPA1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3sz3 TRYPTOPHANYL-TRNA
SYNTHETASE
(Vibrio
cholerae) 		5 / 9 GLN A  11
VAL A  42
ASP A 135
ILE A 136
VAL A 146
 TRP  A 401 (-3.2A)
TRP  A 401 (-4.7A)
TRP  A 401 (-4.0A)
None
None
 0.97A 3fi0A-3sz3A:
37.6		 3fi0A-3sz3A:
52.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_A_TRPA1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3sz3 TRYPTOPHANYL-TRNA
SYNTHETASE
(Vibrio
cholerae) 		6 / 9 GLY A   9
VAL A  42
ASP A 135
ILE A 136
VAL A 144
VAL A 146
 TRP  A 401 (-3.8A)
TRP  A 401 (-4.7A)
TRP  A 401 (-4.0A)
None
TRP  A 401 (-4.9A)
None
 0.57A 3fi0A-3sz3A:
37.6		 3fi0A-3sz3A:
52.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_A_TRPA1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3sz3 TRYPTOPHANYL-TRNA
SYNTHETASE
(Vibrio
cholerae) 		6 / 9 VAL A  42
ASP A 135
ILE A 136
VAL A 144
VAL A 146
GLN A 150
 TRP  A 401 (-4.7A)
TRP  A 401 (-4.0A)
None
TRP  A 401 (-4.9A)
None
TRP  A 401 (-3.8A)
 1.15A 3fi0A-3sz3A:
37.6		 3fi0A-3sz3A:
52.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_B_TRPB1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3sz3 TRYPTOPHANYL-TRNA
SYNTHETASE
(Vibrio
cholerae) 		6 / 8 GLY A   9
VAL A  42
ASP A 135
ILE A 136
VAL A 144
VAL A 146
 TRP  A 401 (-3.8A)
TRP  A 401 (-4.7A)
TRP  A 401 (-4.0A)
None
TRP  A 401 (-4.9A)
None
 0.54A 3fi0B-3sz3A:
37.3		 3fi0B-3sz3A:
52.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_B_TRPB1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3sz3 TRYPTOPHANYL-TRNA
SYNTHETASE
(Vibrio
cholerae) 		6 / 8 VAL A  42
ASP A 135
ILE A 136
VAL A 144
VAL A 146
GLN A 150
 TRP  A 401 (-4.7A)
TRP  A 401 (-4.0A)
None
TRP  A 401 (-4.9A)
None
TRP  A 401 (-3.8A)
 1.05A 3fi0B-3sz3A:
37.3		 3fi0B-3sz3A:
52.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_C_TRPC1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3sz3 TRYPTOPHANYL-TRNA
SYNTHETASE
(Vibrio
cholerae) 		7 / 9 GLY A   9
GLN A  11
VAL A  42
ASP A 135
ILE A 136
VAL A 144
VAL A 146
 TRP  A 401 (-3.8A)
TRP  A 401 (-3.2A)
TRP  A 401 (-4.7A)
TRP  A 401 (-4.0A)
None
TRP  A 401 (-4.9A)
None
 0.83A 3fi0C-3sz3A:
37.7		 3fi0C-3sz3A:
52.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_C_TRPC1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3sz3 TRYPTOPHANYL-TRNA
SYNTHETASE
(Vibrio
cholerae) 		6 / 9 VAL A  42
ASP A 135
ILE A 136
VAL A 144
VAL A 146
GLN A 150
 TRP  A 401 (-4.7A)
TRP  A 401 (-4.0A)
None
TRP  A 401 (-4.9A)
None
TRP  A 401 (-3.8A)
 1.14A 3fi0C-3sz3A:
37.7		 3fi0C-3sz3A:
52.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_D_TRPD1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3sz3 TRYPTOPHANYL-TRNA
SYNTHETASE
(Vibrio
cholerae) 		5 / 9 GLY A   9
GLN A  11
VAL A  42
ASP A 135
ILE A 136
 TRP  A 401 (-3.8A)
TRP  A 401 (-3.2A)
TRP  A 401 (-4.7A)
TRP  A 401 (-4.0A)
None
 0.81A 3fi0D-3sz3A:
38.5		 3fi0D-3sz3A:
52.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_D_TRPD1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3sz3 TRYPTOPHANYL-TRNA
SYNTHETASE
(Vibrio
cholerae) 		6 / 9 GLY A   9
VAL A  42
ASP A 135
ILE A 136
VAL A 144
VAL A 146
 TRP  A 401 (-3.8A)
TRP  A 401 (-4.7A)
TRP  A 401 (-4.0A)
None
TRP  A 401 (-4.9A)
None
 0.57A 3fi0D-3sz3A:
38.5		 3fi0D-3sz3A:
52.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_D_TRPD1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3sz3 TRYPTOPHANYL-TRNA
SYNTHETASE
(Vibrio
cholerae) 		6 / 9 VAL A  42
ASP A 135
ILE A 136
VAL A 144
VAL A 146
GLN A 150
 TRP  A 401 (-4.7A)
TRP  A 401 (-4.0A)
None
TRP  A 401 (-4.9A)
None
TRP  A 401 (-3.8A)
 1.11A 3fi0D-3sz3A:
38.5		 3fi0D-3sz3A:
52.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_E_TRPE1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3sz3 TRYPTOPHANYL-TRNA
SYNTHETASE
(Vibrio
cholerae) 		4 / 7 ASP A 135
ILE A 136
VAL A 144
GLN A 150
 TRP  A 401 (-4.0A)
None
TRP  A 401 (-4.9A)
TRP  A 401 (-3.8A)
 0.87A 3fi0E-3sz3A:
36.6		 3fi0E-3sz3A:
52.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_E_TRPE1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3sz3 TRYPTOPHANYL-TRNA
SYNTHETASE
(Vibrio
cholerae) 		5 / 7 GLY A   9
VAL A  42
ASP A 135
ILE A 136
VAL A 144
 TRP  A 401 (-3.8A)
TRP  A 401 (-4.7A)
TRP  A 401 (-4.0A)
None
TRP  A 401 (-4.9A)
 0.42A 3fi0E-3sz3A:
36.6		 3fi0E-3sz3A:
52.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_F_TRPF1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3sz3 TRYPTOPHANYL-TRNA
SYNTHETASE
(Vibrio
cholerae) 		5 / 9 GLY A   9
GLN A  11
VAL A  42
ASP A 135
ILE A 136
 TRP  A 401 (-3.8A)
TRP  A 401 (-3.2A)
TRP  A 401 (-4.7A)
TRP  A 401 (-4.0A)
None
 0.79A 3fi0F-3sz3A:
37.3		 3fi0F-3sz3A:
52.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_F_TRPF1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3sz3 TRYPTOPHANYL-TRNA
SYNTHETASE
(Vibrio
cholerae) 		6 / 9 GLY A   9
VAL A  42
ASP A 135
ILE A 136
VAL A 144
VAL A 146
 TRP  A 401 (-3.8A)
TRP  A 401 (-4.7A)
TRP  A 401 (-4.0A)
None
TRP  A 401 (-4.9A)
None
 0.60A 3fi0F-3sz3A:
37.3		 3fi0F-3sz3A:
52.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_F_TRPF1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3sz3 TRYPTOPHANYL-TRNA
SYNTHETASE
(Vibrio
cholerae) 		6 / 9 VAL A  42
ASP A 135
ILE A 136
VAL A 144
VAL A 146
GLN A 150
 TRP  A 401 (-4.7A)
TRP  A 401 (-4.0A)
None
TRP  A 401 (-4.9A)
None
TRP  A 401 (-3.8A)
 1.11A 3fi0F-3sz3A:
37.3		 3fi0F-3sz3A:
52.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_G_TRPG1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3sz3 TRYPTOPHANYL-TRNA
SYNTHETASE
(Vibrio
cholerae) 		5 / 8 ASP A 135
ILE A 136
VAL A 144
VAL A 146
GLN A 150
 TRP  A 401 (-4.0A)
None
TRP  A 401 (-4.9A)
None
TRP  A 401 (-3.8A)
 1.26A 3fi0G-3sz3A:
38.5		 3fi0G-3sz3A:
52.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_G_TRPG1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3sz3 TRYPTOPHANYL-TRNA
SYNTHETASE
(Vibrio
cholerae) 		6 / 8 GLY A   9
VAL A  42
ASP A 135
ILE A 136
VAL A 144
VAL A 146
 TRP  A 401 (-3.8A)
TRP  A 401 (-4.7A)
TRP  A 401 (-4.0A)
None
TRP  A 401 (-4.9A)
None
 0.62A 3fi0G-3sz3A:
38.5		 3fi0G-3sz3A:
52.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_H_TRPH1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3sz3 TRYPTOPHANYL-TRNA
SYNTHETASE
(Vibrio
cholerae) 		6 / 9 GLY A   9
GLN A  11
VAL A  42
ASP A 135
ILE A 136
VAL A 146
 TRP  A 401 (-3.8A)
TRP  A 401 (-3.2A)
TRP  A 401 (-4.7A)
TRP  A 401 (-4.0A)
None
None
 0.90A 3fi0H-3sz3A:
38.5		 3fi0H-3sz3A:
52.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_H_TRPH1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3sz3 TRYPTOPHANYL-TRNA
SYNTHETASE
(Vibrio
cholerae) 		6 / 9 GLY A   9
VAL A  42
ASP A 135
ILE A 136
VAL A 144
VAL A 146
 TRP  A 401 (-3.8A)
TRP  A 401 (-4.7A)
TRP  A 401 (-4.0A)
None
TRP  A 401 (-4.9A)
None
 0.56A 3fi0H-3sz3A:
38.5		 3fi0H-3sz3A:
52.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_H_TRPH1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3sz3 TRYPTOPHANYL-TRNA
SYNTHETASE
(Vibrio
cholerae) 		6 / 9 VAL A  42
ASP A 135
ILE A 136
VAL A 144
VAL A 146
GLN A 150
 TRP  A 401 (-4.7A)
TRP  A 401 (-4.0A)
None
TRP  A 401 (-4.9A)
None
TRP  A 401 (-3.8A)
 1.09A 3fi0H-3sz3A:
38.5		 3fi0H-3sz3A:
52.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_J_TRPJ1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3sz3 TRYPTOPHANYL-TRNA
SYNTHETASE
(Vibrio
cholerae) 		6 / 9 GLY A   9
VAL A  42
ASP A 135
ILE A 136
VAL A 144
VAL A 146
 TRP  A 401 (-3.8A)
TRP  A 401 (-4.7A)
TRP  A 401 (-4.0A)
None
TRP  A 401 (-4.9A)
None
 0.59A 3fi0J-3sz3A:
38.4		 3fi0J-3sz3A:
52.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_J_TRPJ1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3sz3 TRYPTOPHANYL-TRNA
SYNTHETASE
(Vibrio
cholerae) 		6 / 9 VAL A  42
ASP A 135
ILE A 136
VAL A 144
VAL A 146
GLN A 150
 TRP  A 401 (-4.7A)
TRP  A 401 (-4.0A)
None
TRP  A 401 (-4.9A)
None
TRP  A 401 (-3.8A)
 1.19A 3fi0J-3sz3A:
38.4		 3fi0J-3sz3A:
52.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_K_TRPK1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3sz3 TRYPTOPHANYL-TRNA
SYNTHETASE
(Vibrio
cholerae) 		5 / 9 GLN A  11
VAL A  42
ASP A 135
ILE A 136
VAL A 146
 TRP  A 401 (-3.2A)
TRP  A 401 (-4.7A)
TRP  A 401 (-4.0A)
None
None
 0.92A 3fi0K-3sz3A:
37.2		 3fi0K-3sz3A:
52.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_K_TRPK1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3sz3 TRYPTOPHANYL-TRNA
SYNTHETASE
(Vibrio
cholerae) 		6 / 9 GLY A   9
VAL A  42
ASP A 135
ILE A 136
VAL A 144
VAL A 146
 TRP  A 401 (-3.8A)
TRP  A 401 (-4.7A)
TRP  A 401 (-4.0A)
None
TRP  A 401 (-4.9A)
None
 0.49A 3fi0K-3sz3A:
37.2		 3fi0K-3sz3A:
52.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_K_TRPK1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3sz3 TRYPTOPHANYL-TRNA
SYNTHETASE
(Vibrio
cholerae) 		6 / 9 VAL A  42
ASP A 135
ILE A 136
VAL A 144
VAL A 146
GLN A 150
 TRP  A 401 (-4.7A)
TRP  A 401 (-4.0A)
None
TRP  A 401 (-4.9A)
None
TRP  A 401 (-3.8A)
 1.08A 3fi0K-3sz3A:
37.2		 3fi0K-3sz3A:
52.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_L_TRPL1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3sz3 TRYPTOPHANYL-TRNA
SYNTHETASE
(Vibrio
cholerae) 		5 / 9 GLN A  11
VAL A  42
ASP A 135
ILE A 136
VAL A 146
 TRP  A 401 (-3.2A)
TRP  A 401 (-4.7A)
TRP  A 401 (-4.0A)
None
None
 1.04A 3fi0L-3sz3A:
38.2		 3fi0L-3sz3A:
52.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_L_TRPL1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3sz3 TRYPTOPHANYL-TRNA
SYNTHETASE
(Vibrio
cholerae) 		6 / 9 GLY A   9
VAL A  42
ASP A 135
ILE A 136
VAL A 144
VAL A 146
 TRP  A 401 (-3.8A)
TRP  A 401 (-4.7A)
TRP  A 401 (-4.0A)
None
TRP  A 401 (-4.9A)
None
 0.63A 3fi0L-3sz3A:
38.2		 3fi0L-3sz3A:
52.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_L_TRPL1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3sz3 TRYPTOPHANYL-TRNA
SYNTHETASE
(Vibrio
cholerae) 		6 / 9 VAL A  42
ASP A 135
ILE A 136
VAL A 144
VAL A 146
GLN A 150
 TRP  A 401 (-4.7A)
TRP  A 401 (-4.0A)
None
TRP  A 401 (-4.9A)
None
TRP  A 401 (-3.8A)
 1.13A 3fi0L-3sz3A:
38.2		 3fi0L-3sz3A:
52.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_M_TRPM1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3sz3 TRYPTOPHANYL-TRNA
SYNTHETASE
(Vibrio
cholerae) 		5 / 9 GLN A  11
VAL A  42
ASP A 135
ILE A 136
VAL A 146
 TRP  A 401 (-3.2A)
TRP  A 401 (-4.7A)
TRP  A 401 (-4.0A)
None
None
 1.02A 3fi0M-3sz3A:
38.3		 3fi0M-3sz3A:
52.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_M_TRPM1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3sz3 TRYPTOPHANYL-TRNA
SYNTHETASE
(Vibrio
cholerae) 		6 / 9 GLY A   9
VAL A  42
ASP A 135
ILE A 136
VAL A 144
VAL A 146
 TRP  A 401 (-3.8A)
TRP  A 401 (-4.7A)
TRP  A 401 (-4.0A)
None
TRP  A 401 (-4.9A)
None
 0.56A 3fi0M-3sz3A:
38.3		 3fi0M-3sz3A:
52.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_M_TRPM1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3sz3 TRYPTOPHANYL-TRNA
SYNTHETASE
(Vibrio
cholerae) 		6 / 9 VAL A  42
ASP A 135
ILE A 136
VAL A 144
VAL A 146
GLN A 150
 TRP  A 401 (-4.7A)
TRP  A 401 (-4.0A)
None
TRP  A 401 (-4.9A)
None
TRP  A 401 (-3.8A)
 1.13A 3fi0M-3sz3A:
38.3		 3fi0M-3sz3A:
52.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_N_TRPN1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3sz3 TRYPTOPHANYL-TRNA
SYNTHETASE
(Vibrio
cholerae) 		6 / 9 GLY A   9
GLN A  11
VAL A  42
ASP A 135
ILE A 136
VAL A 146
 TRP  A 401 (-3.8A)
TRP  A 401 (-3.2A)
TRP  A 401 (-4.7A)
TRP  A 401 (-4.0A)
None
None
 0.88A 3fi0N-3sz3A:
38.1		 3fi0N-3sz3A:
52.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_N_TRPN1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3sz3 TRYPTOPHANYL-TRNA
SYNTHETASE
(Vibrio
cholerae) 		6 / 9 GLY A   9
VAL A  42
ASP A 135
ILE A 136
VAL A 144
VAL A 146
 TRP  A 401 (-3.8A)
TRP  A 401 (-4.7A)
TRP  A 401 (-4.0A)
None
TRP  A 401 (-4.9A)
None
 0.59A 3fi0N-3sz3A:
38.1		 3fi0N-3sz3A:
52.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_N_TRPN1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3sz3 TRYPTOPHANYL-TRNA
SYNTHETASE
(Vibrio
cholerae) 		6 / 9 VAL A  42
ASP A 135
ILE A 136
VAL A 144
VAL A 146
GLN A 150
 TRP  A 401 (-4.7A)
TRP  A 401 (-4.0A)
None
TRP  A 401 (-4.9A)
None
TRP  A 401 (-3.8A)
 1.12A 3fi0N-3sz3A:
38.1		 3fi0N-3sz3A:
52.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_O_TRPO1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3sz3 TRYPTOPHANYL-TRNA
SYNTHETASE
(Vibrio
cholerae) 		5 / 9 GLN A  11
VAL A  42
ASP A 135
ILE A 136
VAL A 146
 TRP  A 401 (-3.2A)
TRP  A 401 (-4.7A)
TRP  A 401 (-4.0A)
None
None
 0.96A 3fi0O-3sz3A:
38.4		 3fi0O-3sz3A:
52.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_O_TRPO1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3sz3 TRYPTOPHANYL-TRNA
SYNTHETASE
(Vibrio
cholerae) 		6 / 9 GLY A   9
VAL A  42
ASP A 135
ILE A 136
VAL A 144
VAL A 146
 TRP  A 401 (-3.8A)
TRP  A 401 (-4.7A)
TRP  A 401 (-4.0A)
None
TRP  A 401 (-4.9A)
None
 0.60A 3fi0O-3sz3A:
38.4		 3fi0O-3sz3A:
52.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_O_TRPO1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3sz3 TRYPTOPHANYL-TRNA
SYNTHETASE
(Vibrio
cholerae) 		6 / 9 VAL A  42
ASP A 135
ILE A 136
VAL A 144
VAL A 146
GLN A 150
 TRP  A 401 (-4.7A)
TRP  A 401 (-4.0A)
None
TRP  A 401 (-4.9A)
None
TRP  A 401 (-3.8A)
 1.19A 3fi0O-3sz3A:
38.4		 3fi0O-3sz3A:
52.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_P_TRPP1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3sz3 TRYPTOPHANYL-TRNA
SYNTHETASE
(Vibrio
cholerae) 		5 / 7 GLY A   9
GLN A  11
VAL A  42
ASP A 135
ILE A 136
 TRP  A 401 (-3.8A)
TRP  A 401 (-3.2A)
TRP  A 401 (-4.7A)
TRP  A 401 (-4.0A)
None
 0.70A 3fi0P-3sz3A:
37.2		 3fi0P-3sz3A:
52.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_Q_TRPQ1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3sz3 TRYPTOPHANYL-TRNA
SYNTHETASE
(Vibrio
cholerae) 		6 / 8 GLY A   9
VAL A  42
ASP A 135
ILE A 136
VAL A 144
VAL A 146
 TRP  A 401 (-3.8A)
TRP  A 401 (-4.7A)
TRP  A 401 (-4.0A)
None
TRP  A 401 (-4.9A)
None
 0.53A 3fi0Q-3sz3A:
38.4		 3fi0Q-3sz3A:
52.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_R_TRPR1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3sz3 TRYPTOPHANYL-TRNA
SYNTHETASE
(Vibrio
cholerae) 		5 / 9 GLY A   9
GLN A  11
VAL A  42
ASP A 135
ILE A 136
 TRP  A 401 (-3.8A)
TRP  A 401 (-3.2A)
TRP  A 401 (-4.7A)
TRP  A 401 (-4.0A)
None
 0.82A 3fi0R-3sz3A:
36.0		 3fi0R-3sz3A:
52.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_R_TRPR1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3sz3 TRYPTOPHANYL-TRNA
SYNTHETASE
(Vibrio
cholerae) 		6 / 9 GLY A   9
VAL A  42
ASP A 135
ILE A 136
VAL A 144
VAL A 146
 TRP  A 401 (-3.8A)
TRP  A 401 (-4.7A)
TRP  A 401 (-4.0A)
None
TRP  A 401 (-4.9A)
None
 0.62A 3fi0R-3sz3A:
36.0		 3fi0R-3sz3A:
52.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_R_TRPR1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3sz3 TRYPTOPHANYL-TRNA
SYNTHETASE
(Vibrio
cholerae) 		6 / 9 VAL A  42
ASP A 135
ILE A 136
VAL A 144
VAL A 146
GLN A 150
 TRP  A 401 (-4.7A)
TRP  A 401 (-4.0A)
None
TRP  A 401 (-4.9A)
None
TRP  A 401 (-3.8A)
 1.15A 3fi0R-3sz3A:
36.0		 3fi0R-3sz3A:
52.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_A_DVAA6_0
(GRAMICIDIN D)		 3sz3 TRYPTOPHANYL-TRNA
SYNTHETASE
(Vibrio
cholerae) 		3 / 3 ALA A  69
VAL A  72
TRP A  28
 None
 0.74A 3l8lA-3sz3A:
undetectable
3l8lB-3sz3A:
undetectable		 3l8lA-3sz3A:
7.19
3l8lB-3sz3A:
7.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UT5_B_LOCB502_1
(TUBULIN BETA CHAIN)		 3sz3 TRYPTOPHANYL-TRNA
SYNTHETASE
(Vibrio
cholerae) 		5 / 12 ALA A 226
ASN A 208
MET A 199
ILE A 219
ILE A  18
 None
 1.05A 3ut5B-3sz3A:
undetectable		 3ut5B-3sz3A:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O2B_B_LOCB503_2
(TUBULIN BETA-2B
CHAIN)		 3sz3 TRYPTOPHANYL-TRNA
SYNTHETASE
(Vibrio
cholerae) 		5 / 12 ALA A 226
ASN A 208
MET A 199
ILE A 219
ILE A  18
 None
 1.03A 4o2bB-3sz3A:
undetectable		 4o2bB-3sz3A:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_E_HCYE900_1
(GLUCOCORTICOID
RECEPTOR)		 3sz3 TRYPTOPHANYL-TRNA
SYNTHETASE
(Vibrio
cholerae) 		5 / 12 LEU A 249
MET A 190
LEU A 192
ILE A 264
PHE A 261
 None
 1.35A 4p6xE-3sz3A:
undetectable		 4p6xE-3sz3A:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ITZ_B_LOCB502_1
(TUBULIN BETA-2B
CHAIN)		 3sz3 TRYPTOPHANYL-TRNA
SYNTHETASE
(Vibrio
cholerae) 		5 / 12 ALA A 226
ASN A 208
MET A 199
ILE A 219
ILE A  18
 None
 1.08A 5itzB-3sz3A:
undetectable		 5itzB-3sz3A:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIO_B_LOCB502_1
(TUBULIN BETA CHAIN)		 3sz3 TRYPTOPHANYL-TRNA
SYNTHETASE
(Vibrio
cholerae) 		5 / 12 ALA A 226
ASN A 208
MET A 199
ILE A 219
ILE A  18
 None
 1.02A 5mioB-3sz3A:
undetectable		 5mioB-3sz3A:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZY_A_CE3A1103_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		 3sz3 TRYPTOPHANYL-TRNA
SYNTHETASE
(Vibrio
cholerae) 		4 / 8 TYR A  39
ASP A  34
VAL A  72
GLY A  71
 None
 0.73A 5nzyA-3sz3A:
undetectable		 5nzyA-3sz3A:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB308_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 3sz3 TRYPTOPHANYL-TRNA
SYNTHETASE
(Vibrio
cholerae) 		3 / 3 LEU A   7
ILE A 136
TYR A 128
 None
None
TRP  A 401 (-4.5A)
 0.57A 5uunB-3sz3A:
undetectable		 5uunB-3sz3A:
22.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5V0I_A_TRPA402_0
(TRYPTOPHAN--TRNA
LIGASE)		 3sz3 TRYPTOPHANYL-TRNA
SYNTHETASE
(Vibrio
cholerae) 		7 / 9 GLN A  11
VAL A  42
MET A 132
ASP A 135
ILE A 136
VAL A 144
GLN A 150
 TRP  A 401 (-3.2A)
TRP  A 401 (-4.7A)
TRP  A 401 (-4.0A)
TRP  A 401 (-4.0A)
None
TRP  A 401 (-4.9A)
TRP  A 401 (-3.8A)
 0.93A 5v0iA-3sz3A:
43.5		 5v0iA-3sz3A:
67.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5V0I_A_TRPA402_0
(TRYPTOPHAN--TRNA
LIGASE)		 3sz3 TRYPTOPHANYL-TRNA
SYNTHETASE
(Vibrio
cholerae) 		7 / 9 GLY A   9
GLN A  11
VAL A  42
MET A 132
ASP A 135
ILE A 136
VAL A 144
 TRP  A 401 (-3.8A)
TRP  A 401 (-3.2A)
TRP  A 401 (-4.7A)
TRP  A 401 (-4.0A)
TRP  A 401 (-4.0A)
None
TRP  A 401 (-4.9A)
 0.56A 5v0iA-3sz3A:
43.5		 5v0iA-3sz3A:
67.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5V0I_B_TRPB402_0
(TRYPTOPHAN--TRNA
LIGASE)		 3sz3 TRYPTOPHANYL-TRNA
SYNTHETASE
(Vibrio
cholerae) 		7 / 9 GLN A  11
VAL A  42
MET A 132
ASP A 135
ILE A 136
VAL A 144
GLN A 150
 TRP  A 401 (-3.2A)
TRP  A 401 (-4.7A)
TRP  A 401 (-4.0A)
TRP  A 401 (-4.0A)
None
TRP  A 401 (-4.9A)
TRP  A 401 (-3.8A)
 0.93A 5v0iB-3sz3A:
43.8		 5v0iB-3sz3A:
67.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5V0I_B_TRPB402_0
(TRYPTOPHAN--TRNA
LIGASE)		 3sz3 TRYPTOPHANYL-TRNA
SYNTHETASE
(Vibrio
cholerae) 		7 / 9 GLY A   9
GLN A  11
VAL A  42
MET A 132
ASP A 135
ILE A 136
VAL A 144
 TRP  A 401 (-3.8A)
TRP  A 401 (-3.2A)
TRP  A 401 (-4.7A)
TRP  A 401 (-4.0A)
TRP  A 401 (-4.0A)
None
TRP  A 401 (-4.9A)
 0.57A 5v0iB-3sz3A:
43.8		 5v0iB-3sz3A:
67.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXI_A_LSNA501_1
(CYTOCHROME P450 2C9)		 3sz3 TRYPTOPHANYL-TRNA
SYNTHETASE
(Vibrio
cholerae) 		5 / 12 VAL A  41
ASN A  20
GLY A  14
ALA A  63
LEU A  79
 None
 1.07A 5xxiA-3sz3A:
undetectable		 5xxiA-3sz3A:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AZ3_1_PAR11803_1
(RRNA ALPHA
RIBOSOMAL PROTEIN
EL18)		 3sz3 TRYPTOPHANYL-TRNA
SYNTHETASE
(Vibrio
cholerae) 		3 / 3 SER A 202
LYS A 201
SER A 200
 None
 0.76A 6az3P-3sz3A:
undetectable		 6az3P-3sz3A:
14.24