SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3sz6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UOB_A_PNNA1311_1
(DEACETOXYCEPHALOSPOR
IN C SYNTHETASE)		 3sz6 CONSERVED DOMAIN
PROTEIN
(Bacillus
anthracis) 		3 / 3 ARG A  54
ARG A  57
ILE A 131
 None
 0.75A 1uobA-3sz6A:
undetectable		 1uobA-3sz6A:
16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A8T_B_ADNB252_1
(U8 SNORNA-BINDING
PROTEIN X29)		 3sz6 CONSERVED DOMAIN
PROTEIN
(Bacillus
anthracis) 		4 / 8 PHE A 146
ILE A 142
ASN A  56
SER A  53
 None
 0.90A 2a8tB-3sz6A:
undetectable		 2a8tB-3sz6A:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LB3_B_4CHB192_0
(DEHALOPEROXIDASE A)		 3sz6 CONSERVED DOMAIN
PROTEIN
(Bacillus
anthracis) 		4 / 6 PHE A  87
PHE A 144
THR A  98
VAL A 112
 None
 1.08A 3lb3B-3sz6A:
undetectable		 3lb3B-3sz6A:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_D_9PLD501_1
(CYTOCHROME P450 2A6)		 3sz6 CONSERVED DOMAIN
PROTEIN
(Bacillus
anthracis) 		5 / 10 PHE A  59
PHE A  76
ILE A 142
GLY A 125
PHE A 146
 None
 1.30A 3t3rD-3sz6A:
undetectable		 3t3rD-3sz6A:
14.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_F_9PLF1_1
(CYTOCHROME P450 2A13)		 3sz6 CONSERVED DOMAIN
PROTEIN
(Bacillus
anthracis) 		5 / 8 PHE A 144
PHE A  42
ALA A  63
PHE A  87
PHE A  59
 None
 1.43A 3t3sF-3sz6A:
undetectable		 3t3sF-3sz6A:
14.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EVR_A_BEZA401_0
(PUTATIVE ABC
TRANSPORTER SUBUNIT,
SUBSTRATE-BINDING
COMPONENT)		 3sz6 CONSERVED DOMAIN
PROTEIN
(Bacillus
anthracis) 		5 / 11 VAL A  78
PHE A 114
ALA A  63
PHE A  42
PHE A 144
 None
 1.45A 4evrA-3sz6A:
undetectable		 4evrA-3sz6A:
17.38