SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3sz7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1XZ1_A_HLTA2001_1 (FERRITIN LIGHT CHAIN)	3sz7	HSC70 COCHAPERONE (SGT) (Aspergillus fumigatus)	4 / 4	LEU A 151 SER A 152 TYR A 150 LEU A 141	None	1.24A	1xz1A-3sz7A: undetectable	1xz1A-3sz7A: 20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1XZ3_A_ICFA201_1 (FERRITIN LIGHT CHAIN)	3sz7	HSC70 COCHAPERONE (SGT) (Aspergillus fumigatus)	4 / 4	LEU A 151 SER A 152 TYR A 150 LEU A 141	None	1.24A	1xz3A-3sz7A: undetectable	1xz3A-3sz7A: 20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XCT_X_CPFX1020_1 (DNA GYRASE SUBUNIT B, DNA GYRASE SUBUNIT A)	3sz7	HSC70 COCHAPERONE (SGT) (Aspergillus fumigatus)	4 / 4	ARG A 222 GLY A 223 GLU A 225 SER A 182	None	1.43A	2xctS-3sz7A: undetectable 2xctU-3sz7A: undetectable	2xctS-3sz7A: 13.27 2xctU-3sz7A: 13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ERG_B_SAMB401_1 (TRNA (ADENINE(58)-N(1))-M ETHYLTRANSFERASE CATALYTIC SUBUNIT TRM61)	3sz7	HSC70 COCHAPERONE (SGT) (Aspergillus fumigatus)	4 / 7	GLY A 215 GLY A 213 GLU A 212 ASP A 218	None	0.70A	5ergB-3sz7A: undetectable	5ergB-3sz7A: 16.93

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1XZ1_A_HLTA2001_1","FERRITIN LIGHT CHAIN","3sz7","HSC70 COCHAPERONE (SGT)","Aspergillus fumigatus",4,"LEU A 151;SER A 152;TYR A 150;LEU A 141","None","1.24A","1xz1A-3sz7A:undetectable","1xz1A-3sz7A:20.43"],["1XZ3_A_ICFA201_1","FERRITIN LIGHT CHAIN","3sz7","HSC70 COCHAPERONE (SGT)","Aspergillus fumigatus",4,"LEU A 151;SER A 152;TYR A 150;LEU A 141","None","1.24A","1xz3A-3sz7A:undetectable","1xz3A-3sz7A:20.43"],["2XCT_X_CPFX1020_1","DNA GYRASE SUBUNIT B, DNA GYRASE SUBUNIT A;DNA GYRASE SUBUNIT B, DNA GYRASE SUBUNIT A","3sz7","HSC70 COCHAPERONE (SGT)","Aspergillus fumigatus",4,"ARG A 222;GLY A 223;GLU A 225;SER A 182","None","1.43A","2xctS-3sz7A:undetectable;2xctU-3sz7A:undetectable","2xctS-3sz7A:13.27;2xctU-3sz7A:13.27"],["5ERG_B_SAMB401_1","TRNA (ADENINE(58)-N(1))-METHYLTRANSFERASE CATALYTIC SUBUNIT TRM61","3sz7","HSC70 COCHAPERONE (SGT)","Aspergillus fumigatus",4,"GLY A 215;GLY A 213;GLU A 212;ASP A 218","None","0.70A","5ergB-3sz7A:undetectable","5ergB-3sz7A:16.93"]]