SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3szb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_A_ADNA601_2
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 3szb ALDEHYDE
DEHYDROGENASE
(Homo
sapiens) 		4 / 5 THR A 420
GLU A 209
THR A 186
HIS A 413
 None
 1.47A 1d4fA-3szbA:
4.2		 1d4fA-3szbA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK1_A_T44A3004_1
(SERUM ALBUMIN)		 3szb ALDEHYDE
DEHYDROGENASE
(Homo
sapiens) 		4 / 6 PHE A 117
LEU A  32
VAL A 125
MET A 124
 None
 1.01A 1hk1A-3szbA:
undetectable		 1hk1A-3szbA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_B_CHDB2503_0
(FERROCHELATASE)		 3szb ALDEHYDE
DEHYDROGENASE
(Homo
sapiens) 		4 / 4 LEU A  77
PRO A  78
LEU A  22
ARG A  20
 None
 1.38A 1hrkB-3szbA:
2.8		 1hrkB-3szbA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QU2_A_MRCA1993_2
(ISOLEUCYL-TRNA
SYNTHETASE)		 3szb ALDEHYDE
DEHYDROGENASE
(Homo
sapiens) 		3 / 3 GLU A  61
TRP A  56
LYS A 137
 None
 1.26A 1qu2A-3szbA:
undetectable		 1qu2A-3szbA:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RLB_E_REAE176_1
(RETINOL BINDING
PROTEIN)		 3szb ALDEHYDE
DEHYDROGENASE
(Homo
sapiens) 		5 / 10 ALA A 150
VAL A  63
MET A 145
LEU A  47
GLN A 155
 None
 1.12A 1rlbE-3szbA:
undetectable		 1rlbE-3szbA:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S19_A_MC9A500_0
(VITAMIN D3 RECEPTOR)		 3szb ALDEHYDE
DEHYDROGENASE
(Homo
sapiens) 		5 / 12 LEU A  29
LEU A  67
VAL A  66
LEU A 136
LEU A 149
 None
 1.14A 1s19A-3szbA:
undetectable		 1s19A-3szbA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W0G_A_MYTA1499_1
(CYTOCHROME P450 3A4)		 3szb ALDEHYDE
DEHYDROGENASE
(Homo
sapiens) 		4 / 6 SER A 367
ILE A 373
THR A 380
ALA A 350
 None
 0.89A 1w0gA-3szbA:
undetectable		 1w0gA-3szbA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZEA_A_DHIA6_0
(MONOCLONAL
ANTI-CHOLERA TOXIN
IGG1 KAPPA ANTIBODY,
H CHAIN
MONOCLONAL
ANTI-CHOLERA TOXIN
IGG1 KAPPA ANTIBODY,
L CHAIN
SHORT SYNTHETIC
D-AMINO ACID PEPTIDE
D2)		 3szb ALDEHYDE
DEHYDROGENASE
(Homo
sapiens) 		3 / 3 TRP A 233
ARG A 229
PHE A 270
 None
 1.43A 1zeaH-3szbA:
undetectable
1zeaL-3szbA:
undetectable		 1zeaH-3szbA:
18.31
1zeaL-3szbA:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_F_SAMF301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3szb ALDEHYDE
DEHYDROGENASE
(Homo
sapiens) 		3 / 3 LYS A 415
ASP A  83
CYH A 427
 None
 1.15A 2br4F-3szbA:
3.6		 2br4F-3szbA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DM6_A_IMNA1401_1
(NADP-DEPENDENT
LEUKOTRIENE B4
12-HYDROXYDEHYDROGEN
ASE)		 3szb ALDEHYDE
DEHYDROGENASE
(Homo
sapiens) 		5 / 10 ILE A 351
ALA A 350
ILE A 373
GLU A 379
ILE A 377
 None
 1.35A 2dm6A-3szbA:
4.9
2dm6B-3szbA:
4.8		 2dm6A-3szbA:
21.04
2dm6B-3szbA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJF_A_ADNA2001_1
(235AA LONG
HYPOTHETICAL
BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 3szb ALDEHYDE
DEHYDROGENASE
(Homo
sapiens) 		4 / 7 TRP A  80
GLU A 419
ALA A 129
ALA A 130
 None
 0.95A 2ejfA-3szbA:
undetectable		 2ejfA-3szbA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GJ5_A_VD3A163_1
(BETA-LACTOGLOBULIN)		 3szb ALDEHYDE
DEHYDROGENASE
(Homo
sapiens) 		5 / 12 VAL A 218
ILE A 249
ILE A 341
ILE A 319
ALA A 303
 None
 0.88A 2gj5A-3szbA:
undetectable		 2gj5A-3szbA:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA4_A_ACHA546_0
(ACETYLCHOLINESTERASE)		 3szb ALDEHYDE
DEHYDROGENASE
(Homo
sapiens) 		4 / 8 TRP A  80
GLU A  69
HIS A 397
GLY A 414
 None
 1.12A 2ha4A-3szbA:
undetectable		 2ha4A-3szbA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA4_B_ACHB603_0
(ACETYLCHOLINESTERASE)		 3szb ALDEHYDE
DEHYDROGENASE
(Homo
sapiens) 		4 / 7 TRP A  80
GLU A  69
HIS A 397
GLY A 414
 None
 1.12A 2ha4B-3szbA:
undetectable		 2ha4B-3szbA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_B_CHDB1604_0
(FERROCHELATASE)		 3szb ALDEHYDE
DEHYDROGENASE
(Homo
sapiens) 		4 / 4 LEU A  77
PRO A  78
LEU A  22
ARG A  20
 None
 1.38A 2hrcB-3szbA:
2.6		 2hrcB-3szbA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNJ_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3szb ALDEHYDE
DEHYDROGENASE
(Homo
sapiens) 		4 / 4 LEU A  77
PRO A  78
LEU A  22
ARG A  20
 None
 1.39A 2pnjB-3szbA:
2.7		 2pnjB-3szbA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_B_SAMB400_0
(UNCHARACTERIZED
PROTEIN TFU_2867)		 3szb ALDEHYDE
DEHYDROGENASE
(Homo
sapiens) 		5 / 12 ALA A 362
GLY A 402
GLY A 383
ILE A 394
GLY A 408
 None
 0.99A 2qe6B-3szbA:
3.6		 2qe6B-3szbA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAX_B_CSCB1384_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 3szb ALDEHYDE
DEHYDROGENASE
(Homo
sapiens) 		5 / 12 LEU A 119
THR A 186
TYR A 412
LYS A 416
HIS A 413
 I1E  A1001 ( 4.8A)
None
None
None
None
 1.39A 2vaxB-3szbA:
0.0		 2vaxB-3szbA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAX_I_CSCI1384_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 3szb ALDEHYDE
DEHYDROGENASE
(Homo
sapiens) 		5 / 12 LEU A 119
THR A 186
TYR A 412
LYS A 416
HIS A 413
 I1E  A1001 ( 4.8A)
None
None
None
None
 1.41A 2vaxI-3szbA:
0.0		 2vaxI-3szbA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YDO_A_ADNA400_1
(ADENOSINE RECEPTOR
A2A)		 3szb ALDEHYDE
DEHYDROGENASE
(Homo
sapiens) 		5 / 12 LEU A 119
LEU A  51
ASN A 238
ILE A 285
SER A 142
 I1E  A1001 ( 4.8A)
None
None
None
None
 1.29A 2ydoA-3szbA:
undetectable		 2ydoA-3szbA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YDO_A_ADNA400_1
(ADENOSINE RECEPTOR
A2A)		 3szb ALDEHYDE
DEHYDROGENASE
(Homo
sapiens) 		5 / 12 PHE A 335
LEU A  51
ASN A 238
ILE A 285
SER A 142
 None
 1.22A 2ydoA-3szbA:
undetectable		 2ydoA-3szbA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZGW_B_ADNB1302_1
(BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 3szb ALDEHYDE
DEHYDROGENASE
(Homo
sapiens) 		4 / 6 TRP A  80
GLU A 419
ALA A 129
ALA A 130
 None
 0.96A 2zgwB-3szbA:
undetectable		 2zgwB-3szbA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCO_A_CHDA3_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3szb ALDEHYDE
DEHYDROGENASE
(Homo
sapiens) 		4 / 4 LEU A  77
PRO A  78
LEU A  22
ARG A  20
 None
 1.37A 3hcoA-3szbA:
2.7		 3hcoA-3szbA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCO_B_CHDB1_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3szb ALDEHYDE
DEHYDROGENASE
(Homo
sapiens) 		4 / 4 LEU A  77
PRO A  78
LEU A  22
ARG A  20
 None
 1.22A 3hcoB-3szbA:
undetectable		 3hcoB-3szbA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCR_A_CHDA424_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3szb ALDEHYDE
DEHYDROGENASE
(Homo
sapiens) 		4 / 8 ARG A 292
PRO A 340
GLY A 336
PRO A 337
 None
 0.92A 3hcrA-3szbA:
2.2		 3hcrA-3szbA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O94_D_NCAD192_0
(NICOTINAMIDASE)		 3szb ALDEHYDE
DEHYDROGENASE
(Homo
sapiens) 		5 / 11 PHE A 117
LEU A  43
TYR A 156
LEU A 149
ILE A 152
 None
 1.45A 3o94D-3szbA:
2.8		 3o94D-3szbA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_A_PFLA319_1
(GLR4197 PROTEIN)		 3szb ALDEHYDE
DEHYDROGENASE
(Homo
sapiens) 		4 / 7 PRO A 138
LEU A  43
THR A 120
ILE A 121
 None
 0.86A 3p50A-3szbA:
undetectable		 3p50A-3szbA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_B_PFLB319_1
(GLR4197 PROTEIN)		 3szb ALDEHYDE
DEHYDROGENASE
(Homo
sapiens) 		4 / 7 PRO A 138
LEU A  43
THR A 120
ILE A 121
 None
 0.87A 3p50B-3szbA:
undetectable		 3p50B-3szbA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_C_PFLC319_1
(GLR4197 PROTEIN)		 3szb ALDEHYDE
DEHYDROGENASE
(Homo
sapiens) 		4 / 7 PRO A 138
LEU A  43
THR A 120
ILE A 121
 None
 0.86A 3p50C-3szbA:
undetectable		 3p50C-3szbA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_D_PFLD320_1
(GLR4197 PROTEIN)		 3szb ALDEHYDE
DEHYDROGENASE
(Homo
sapiens) 		4 / 7 PRO A 138
LEU A  43
THR A 120
ILE A 121
 None
 0.87A 3p50D-3szbA:
undetectable		 3p50D-3szbA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_E_PFLE319_1
(GLR4197 PROTEIN)		 3szb ALDEHYDE
DEHYDROGENASE
(Homo
sapiens) 		4 / 7 PRO A 138
LEU A  43
THR A 120
ILE A 121
 None
 0.92A 3p50E-3szbA:
undetectable		 3p50E-3szbA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BLV_B_SAMB1281_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)		 3szb ALDEHYDE
DEHYDROGENASE
(Homo
sapiens) 		5 / 12 HIS A 393
GLY A 403
GLY A 384
LEU A 208
GLY A 187
 None
 1.11A 4blvB-3szbA:
4.1		 4blvB-3szbA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EM2_A_SALA504_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SAR2349)		 3szb ALDEHYDE
DEHYDROGENASE
(Homo
sapiens) 		4 / 8 GLY A 295
LEU A 296
ILE A 297
ILE A 315
 None
 0.71A 4em2A-3szbA:
undetectable		 4em2A-3szbA:
16.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F93_B_SANB3004_1
(U5 SMALL NUCLEAR
RIBONUCLEOPROTEIN
200 KDA HELICASE)		 3szb ALDEHYDE
DEHYDROGENASE
(Homo
sapiens) 		4 / 8 GLU A  62
GLN A 241
GLY A 240
SER A 239
 None
 0.99A 4f93B-3szbA:
3.6		 4f93B-3szbA:
14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O8F_B_BRLB501_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3szb ALDEHYDE
DEHYDROGENASE
(Homo
sapiens) 		4 / 6 ILE A 128
GLY A 126
ILE A  70
LEU A 157
 None
 0.76A 4o8fB-3szbA:
undetectable		 4o8fB-3szbA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TVT_A_ASCA303_0
(THAUMATIN-1)		 3szb ALDEHYDE
DEHYDROGENASE
(Homo
sapiens) 		4 / 7 GLU A 269
SER A 266
LYS A 262
VAL A 226
 None
 0.99A 4tvtA-3szbA:
undetectable		 4tvtA-3szbA:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E4D_B_BEZB201_0
(HYDROXYNITRILE LYASE)		 3szb ALDEHYDE
DEHYDROGENASE
(Homo
sapiens) 		5 / 11 VAL A  63
TYR A 156
ILE A 153
ILE A 121
LEU A  43
 None
 1.12A 5e4dB-3szbA:
undetectable		 5e4dB-3szbA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD4_B_STIB602_1
(TYROSINE-PROTEIN
KINASE ABL1)		 3szb ALDEHYDE
DEHYDROGENASE
(Homo
sapiens) 		4 / 6 LEU A  77
VAL A  63
PHE A 418
GLY A 131
 None
 0.89A 6hd4B-3szbA:
undetectable		 6hd4B-3szbA:
13.40