SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3t0q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDU_B_ESTB354_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE)		 3t0q AGR253WP
(Eremothecium
gossypii) 		4 / 8 LEU A 664
TYR A 663
MET A 585
VAL A 583
 None
 1.07A 1fduB-3t0qA:
undetectable		 1fduB-3t0qA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KB9_A_PCFA514_0
(CYTOCHROME B
CYTOCHROME C1, HEME
PROTEIN
UBIQUINOL-CYTOCHROME
C REDUCTASE COMPLEX
CORE PROTEIN I
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)		 3t0q AGR253WP
(Eremothecium
gossypii) 		4 / 8 SER A 668
ILE A 541
VAL A 606
SER A 580
 None
 1.13A 1kb9A-3t0qA:
undetectable
1kb9C-3t0qA:
undetectable
1kb9D-3t0qA:
undetectable
1kb9E-3t0qA:
undetectable		 1kb9A-3t0qA:
22.39
1kb9C-3t0qA:
21.48
1kb9D-3t0qA:
19.89
1kb9E-3t0qA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXF_A_DZPA2001_1
(SERUM ALBUMIN)		 3t0q AGR253WP
(Eremothecium
gossypii) 		5 / 12 ASN A 366
TYR A 370
LEU A 676
VAL A 447
LEU A 437
 None
 1.25A 2bxfA-3t0qA:
undetectable		 2bxfA-3t0qA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GEH_A_NHYA300_1
(CARBONIC ANHYDRASE 2)		 3t0q AGR253WP
(Eremothecium
gossypii) 		4 / 8 HIS A 581
VAL A 583
VAL A 606
LEU A 665
 EDO  A   1 ( 4.0A)
None
None
None
 0.87A 2gehA-3t0qA:
undetectable		 2gehA-3t0qA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLC_A_GLYA333_0
(CHOLOYLGLYCINE
HYDROLASE)		 3t0q AGR253WP
(Eremothecium
gossypii) 		3 / 3 ASN A 465
ASN A 427
ARG A 372
 None
None
ADP  A 999 (-3.2A)
 0.67A 2rlcA-3t0qA:
undetectable		 2rlcA-3t0qA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WLJ_A_SPMA1303_1
(POTASSIUM CHANNEL)		 3t0q AGR253WP
(Eremothecium
gossypii) 		3 / 3 ARG A 374
ARG A 372
PRO A 375
 ADP  A 999 (-4.6A)
ADP  A 999 (-3.2A)
ADP  A 999 (-4.4A)
 1.11A 2wljA-3t0qA:
1.3		 2wljA-3t0qA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF502_3
(PHOSPHOLIPASE A2)		 3t0q AGR253WP
(Eremothecium
gossypii) 		5 / 12 VAL A 606
LEU A 605
SER A 668
SER A 673
THR A 675
 None
 1.23A 3bjwF-3t0qA:
undetectable		 3bjwF-3t0qA:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXX_C_DR7C100_2
(HIV-1 PROTEASE)		 3t0q AGR253WP
(Eremothecium
gossypii) 		5 / 11 LEU A 676
ASP A 607
ILE A 471
GLY A 469
ILE A 449
 None
MG  A 997 ( 4.2A)
None
None
None
 0.96A 3oxxD-3t0qA:
undetectable		 3oxxD-3t0qA:
12.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA602_1
(CHITINASE)		 3t0q AGR253WP
(Eremothecium
gossypii) 		3 / 3 TRP A 490
GLU A 597
ASP A 443
 None
 1.03A 5gqbA-3t0qA:
undetectable		 5gqbA-3t0qA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_A_RCXA601_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3t0q AGR253WP
(Eremothecium
gossypii) 		3 / 3 ARG A 657
ILE A 654
PHE A 656
 None
 0.74A 5kirA-3t0qA:
undetectable		 5kirA-3t0qA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KU6_A_MZMA301_1
(CARBONIC ANHYDRASE 4)		 3t0q AGR253WP
(Eremothecium
gossypii) 		5 / 10 HIS A 581
VAL A 583
VAL A 606
LEU A 665
THR A 662
 EDO  A   1 ( 4.0A)
None
None
None
None
 1.45A 5ku6A-3t0qA:
undetectable		 5ku6A-3t0qA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		 3t0q AGR253WP
(Eremothecium
gossypii) 		4 / 8 HIS A 581
VAL A 583
VAL A 606
LEU A 665
 EDO  A   1 ( 4.0A)
None
None
None
 0.78A 5tt3F-3t0qA:
undetectable		 5tt3F-3t0qA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U4S_B_BEZB301_0
(PUTATIVE SHORT CHAIN
DEHYDROGENASE)		 3t0q AGR253WP
(Eremothecium
gossypii) 		4 / 8 SER A 441
ILE A 588
LEU A 442
MET A 494
 None
 0.94A 5u4sB-3t0qA:
undetectable		 5u4sB-3t0qA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BEC_C_RBTC601_1
(SCAFFOLD PROTEIN D13)		 3t0q AGR253WP
(Eremothecium
gossypii) 		5 / 12 VAL A 701
GLU A 612
VAL A 583
PHE A 697
ILE A 501
 None
 1.39A 6becA-3t0qA:
undetectable
6becB-3t0qA:
undetectable
6becC-3t0qA:
undetectable		 6becA-3t0qA:
20.89
6becB-3t0qA:
20.89
6becC-3t0qA:
20.89