SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3t0y'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TGV_B_BEZB1_0
(HEME-BINDING PROTEIN
HUTZ)		 3t0y RESPONSE REGULATOR
NEPR
(Caulobacter
vibrioides;
Caulobacter
vibrioides) 		4 / 6 GLN A  39
PHE B  54
PRO B  51
LEU A  25
 None
 1.19A 3tgvB-3t0yA:
undetectable		 3tgvB-3t0yA:
23.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TGV_D_BEZD1_0
(HEME-BINDING PROTEIN
HUTZ)		 3t0y RESPONSE REGULATOR
NEPR
(Caulobacter
vibrioides;
Caulobacter
vibrioides) 		4 / 6 GLN A  39
PHE B  54
PRO B  51
LEU A  25
 None
 1.28A 3tgvD-3t0yA:
undetectable		 3tgvD-3t0yA:
23.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWZ_B_BEZB301_0
(14-3-3 PROTEIN
ZETA/DELTA)		 3t0y NEPR
(Caulobacter
vibrioides) 		3 / 3 MET B  41
GLN B  40
ARG B  39
 None
 1.04A 5ewzB-3t0yB:
undetectable		 5ewzB-3t0yB:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M35_B_BEZB302_0
(14-3-3 PROTEIN
ZETA/DELTA)		 3t0y NEPR
(Caulobacter
vibrioides) 		3 / 3 MET B  41
GLN B  40
ARG B  39
 None
 1.08A 5m35B-3t0yB:
undetectable		 5m35B-3t0yB:
15.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M36_A_BEZA303_0
(14-3-3 PROTEIN
ZETA/DELTA)		 3t0y NEPR
(Caulobacter
vibrioides) 		3 / 3 MET B  41
GLN B  40
ARG B  39
 None
 1.12A 5m36A-3t0yB:
undetectable		 5m36A-3t0yB:
15.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FN9_A_BEZA302_0
(14-3-3 PROTEIN
ZETA/DELTA)		 3t0y NEPR
(Caulobacter
vibrioides) 		3 / 3 MET B  41
GLN B  40
ARG B  39
 None
 1.11A 6fn9A-3t0yB:
undetectable		 6fn9A-3t0yB:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FNA_B_BEZB302_0
(14-3-3 PROTEIN
ZETA/DELTA)		 3t0y NEPR
(Caulobacter
vibrioides) 		3 / 3 MET B  41
GLN B  40
ARG B  39
 None
 1.10A 6fnaB-3t0yB:
undetectable		 6fnaB-3t0yB:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FNB_A_BEZA301_0
(14-3-3 PROTEIN
ZETA/DELTA)		 3t0y NEPR
(Caulobacter
vibrioides) 		3 / 3 MET B  41
GLN B  40
ARG B  39
 None
 1.11A 6fnbA-3t0yB:
undetectable		 6fnbA-3t0yB:
15.87