SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3t1b'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BX4_A_ADNA350_2
(PROTEIN (ADENOSINE
KINASE))		 3t1b TRANSCRIPTIONAL
REGULATOR, LYSR
FAMILY
(Vibrio
cholerae) 		3 / 3 LEU A 164
SER A 258
ASN A 201
 None
 0.75A 1bx4A-3t1bA:
undetectable		 1bx4A-3t1bA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7P_A_SALA1001_1
(LYSR-TYPE REGULATORY
PROTEIN)		 3t1b TRANSCRIPTIONAL
REGULATOR, LYSR
FAMILY
(Vibrio
cholerae) 		4 / 6 MET A 236
PRO A 193
GLY A 191
TRP A 197
 None
 1.25A 2y7pA-3t1bA:
9.4		 2y7pA-3t1bA:
23.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL0_A_1UNA201_2
(PROTEASE)		 3t1b TRANSCRIPTIONAL
REGULATOR, LYSR
FAMILY
(Vibrio
cholerae) 		5 / 9 LEU A 124
VAL A 140
ILE A 282
ALA A  97
ILE A  95
 None
 0.87A 3el0B-3t1bA:
undetectable		 3el0B-3t1bA:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_F_TFPF201_1
(PROTEIN S100-A4)		 3t1b TRANSCRIPTIONAL
REGULATOR, LYSR
FAMILY
(Vibrio
cholerae) 		4 / 5 MET A 107
PHE A 142
PHE A 284
PHE A 281
 None
 1.25A 3ko0F-3t1bA:
undetectable
3ko0G-3t1bA:
undetectable		 3ko0F-3t1bA:
18.71
3ko0G-3t1bA:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LOQ_A_ACTA278_0
(UNIVERSAL STRESS
PROTEIN)		 3t1b TRANSCRIPTIONAL
REGULATOR, LYSR
FAMILY
(Vibrio
cholerae) 		3 / 3 SER A 167
GLY A 230
SER A 172
 None
 0.57A 3loqA-3t1bA:
undetectable		 3loqA-3t1bA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_B_9PLB1_1
(CYTOCHROME P450 2A13)		 3t1b TRANSCRIPTIONAL
REGULATOR, LYSR
FAMILY
(Vibrio
cholerae) 		4 / 6 PHE A 281
PHE A 142
ALA A  97
THR A 102
 None
 1.12A 3t3sB-3t1bA:
undetectable		 3t3sB-3t1bA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q15_A_HFGA803_0
(PROLINE--TRNA LIGASE)		 3t1b TRANSCRIPTIONAL
REGULATOR, LYSR
FAMILY
(Vibrio
cholerae) 		5 / 12 LEU A 101
VAL A 160
PRO A 237
PHE A 244
SER A 228
 None
 1.30A 4q15A-3t1bA:
2.4		 4q15A-3t1bA:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q15_B_HFGB803_0
(PROLINE--TRNA LIGASE)		 3t1b TRANSCRIPTIONAL
REGULATOR, LYSR
FAMILY
(Vibrio
cholerae) 		5 / 12 LEU A 101
VAL A 160
PRO A 237
PHE A 244
SER A 228
 None
 1.33A 4q15B-3t1bA:
undetectable		 4q15B-3t1bA:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y8W_C_STRC603_2
(CYTOCHROME P450
21-HYDROXYLASE)		 3t1b TRANSCRIPTIONAL
REGULATOR, LYSR
FAMILY
(Vibrio
cholerae) 		3 / 3 LEU A 220
VAL A 239
ASP A 238
 None
 0.50A 4y8wC-3t1bA:
undetectable		 4y8wC-3t1bA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YDQ_A_HFGA802_0
(PROLINE--TRNA LIGASE)		 3t1b TRANSCRIPTIONAL
REGULATOR, LYSR
FAMILY
(Vibrio
cholerae) 		5 / 12 LEU A 101
VAL A 160
PRO A 237
PHE A 244
SER A 228
 None
 1.29A 4ydqA-3t1bA:
undetectable		 4ydqA-3t1bA:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA309_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 3t1b TRANSCRIPTIONAL
REGULATOR, LYSR
FAMILY
(Vibrio
cholerae) 		4 / 4 LEU A 231
GLY A 230
SER A 228
SER A 225
 None
 1.35A 5uunA-3t1bA:
undetectable		 5uunA-3t1bA:
20.99