SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3t1e'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CBR_A_REAA200_1
(CELLULAR RETINOIC
ACID BINDING PROTEIN
TYPE I)		 3t1e HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		5 / 12 LEU A 498
ALA A 523
PRO A 176
THR A 173
TYR A 186
 None
 1.14A 1cbrA-3t1eA:
undetectable		 1cbrA-3t1eA:
13.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CBR_B_REAB200_1
(CELLULAR RETINOIC
ACID BINDING PROTEIN
TYPE I)		 3t1e HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		5 / 12 LEU A 498
ALA A 523
PRO A 176
THR A 173
TYR A 186
 None
 1.15A 1cbrB-3t1eA:
undetectable		 1cbrB-3t1eA:
13.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TV8_A_SAMA1501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 3t1e HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		4 / 7 THR A 470
THR A 526
SER A 543
VAL A 562
 None
 0.97A 1tv8A-3t1eA:
undetectable		 1tv8A-3t1eA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TV8_B_SAMB2501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 3t1e HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		4 / 7 THR A 470
THR A 526
SER A 543
VAL A 562
 None
 1.08A 1tv8B-3t1eA:
undetectable		 1tv8B-3t1eA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V3E_A_ZMRA1200_1
(HEMAGGLUTININ-NEURAM
INIDASE GLYCOPROTEIN)		 3t1e HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		7 / 10 ARG A 174
GLU A 257
TYR A 298
TYR A 316
GLU A 400
ARG A 415
TYR A 525
 None
 0.70A 1v3eA-3t1eA:
47.7		 1v3eA-3t1eA:
28.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V3E_A_ZMRA1200_1
(HEMAGGLUTININ-NEURAM
INIDASE GLYCOPROTEIN)		 3t1e HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		7 / 10 GLU A 257
TYR A 298
TYR A 316
PHE A 363
GLU A 400
ARG A 415
TYR A 525
 None
 0.43A 1v3eA-3t1eA:
47.7		 1v3eA-3t1eA:
28.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V3E_B_ZMRB2200_1
(HEMAGGLUTININ-NEURAM
INIDASE GLYCOPROTEIN)		 3t1e HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		8 / 10 ARG A 174
GLU A 257
TYR A 298
TYR A 316
PHE A 363
GLU A 400
ARG A 415
TYR A 525
 None
 0.75A 1v3eB-3t1eA:
47.8		 1v3eB-3t1eA:
28.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_A_ZMRA1478_1
(NEURAMINIDASE)		 3t1e HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		4 / 7 SER A 517
SER A 518
SER A 519
ASN A 549
 None
 1.05A 2cmlA-3t1eA:
21.6		 2cmlA-3t1eA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_B_ZMRB2478_1
(NEURAMINIDASE)		 3t1e HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		4 / 8 SER A 517
SER A 518
SER A 519
ASN A 549
 None
 1.08A 2cmlB-3t1eA:
21.7		 2cmlB-3t1eA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_C_ZMRC3478_1
(NEURAMINIDASE)		 3t1e HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		4 / 8 SER A 517
SER A 518
SER A 519
ASN A 549
 None
 1.08A 2cmlC-3t1eA:
21.6		 2cmlC-3t1eA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_D_ZMRD4478_1
(NEURAMINIDASE)		 3t1e HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		4 / 8 SER A 517
SER A 518
SER A 519
ASN A 549
 None
 1.13A 2cmlD-3t1eA:
21.7		 2cmlD-3t1eA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F0Z_A_ZMRA381_1
(SIALIDASE 2)		 3t1e HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		5 / 12 GLU A 257
TYR A 316
GLU A 400
ARG A 415
TYR A 525
 None
 0.65A 2f0zA-3t1eA:
27.9		 2f0zA-3t1eA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FB2_A_SAMA501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 3t1e HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		4 / 8 THR A 470
THR A 526
SER A 543
VAL A 562
 None
 0.98A 2fb2A-3t1eA:
undetectable		 2fb2A-3t1eA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FB2_B_SAMB501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 3t1e HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		4 / 7 THR A 470
THR A 526
SER A 543
VAL A 562
 None
 0.99A 2fb2B-3t1eA:
undetectable		 2fb2B-3t1eA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LS4_H_TCIH220_2
(HEAVY CHAIN OF
ANTIBODY FAB
FRAGMENT
LIGHT CHAIN OF
ANTIBODY FAB
FRAGMENT)		 3t1e HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		4 / 5 TYR A 132
ILE A 544
LEU A 542
PHE A 531
 None
 1.23A 3ls4L-3t1eA:
undetectable		 3ls4L-3t1eA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9H_A_NCAA1163_0
(TANKYRASE-2)		 3t1e HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		4 / 8 GLY A 467
TYR A 469
ALA A 399
SER A 417
 None
 0.79A 3u9hA-3t1eA:
undetectable		 3u9hA-3t1eA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9H_B_NCAB1164_0
(TANKYRASE-2)		 3t1e HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		4 / 8 GLY A 467
TYR A 469
ALA A 399
SER A 417
 None
 0.80A 3u9hB-3t1eA:
undetectable		 3u9hB-3t1eA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BJC_A_RPBA2162_1
(TANKYRASE-2)		 3t1e HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		4 / 8 GLY A 467
TYR A 469
ALA A 399
SER A 417
 None
 0.84A 4bjcA-3t1eA:
undetectable		 4bjcA-3t1eA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYF_A_NCAA1201_0
(TANKYRASE-2)		 3t1e HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		4 / 7 GLY A 467
TYR A 469
ALA A 399
SER A 417
 None
 0.86A 4hyfA-3t1eA:
undetectable		 4hyfA-3t1eA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYF_B_NCAB1201_0
(TANKYRASE-2)		 3t1e HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		4 / 8 GLY A 467
TYR A 469
ALA A 399
SER A 417
 None
 0.87A 4hyfB-3t1eA:
undetectable		 4hyfB-3t1eA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYF_C_NCAC1201_0
(TANKYRASE-2)		 3t1e HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		4 / 8 GLY A 467
TYR A 469
ALA A 399
SER A 417
 None
 0.82A 4hyfC-3t1eA:
undetectable		 4hyfC-3t1eA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMC_A_29JA604_1
(TRANSPORTER)		 3t1e HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		4 / 7 ILE A 226
LEU A 228
ASP A 230
ASP A 229
 None
 1.10A 4mmcA-3t1eA:
undetectable		 4mmcA-3t1eA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZF8_A_MYTA502_1
(BIFUNCTIONAL
P-450/NADPH-P450
REDUCTASE)		 3t1e HEMAGGLUTININ-NEURAM
INIDASE
(Avian
avulavirus
1) 		4 / 6 LEU A 542
ILE A 544
ALA A 545
THR A 489
 None
 0.78A 4zf8A-3t1eA:
undetectable		 4zf8A-3t1eA:
21.60