SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3t1u'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J3J_B_CP6B709_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3t1u PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Azotobacter
vinelandii) 		5 / 9 ALA A  20
PHE A 123
SER A   1
ILE A   2
ILE A  83
 None
 1.36A 1j3jB-3t1uA:
undetectable		 1j3jB-3t1uA:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X70_B_715B801_2
(DIPEPTIDYL PEPTIDASE
IV)		 3t1u PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Azotobacter
vinelandii) 		3 / 3 PHE A 123
TYR A  36
TYR A  30
 None
 0.93A 1x70B-3t1uA:
undetectable		 1x70B-3t1uA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HMY_B_SAMB328_0
(PROTEIN
(CYTOSINE-SPECIFIC
METHYLTRANSFERASE
HHAI))		 3t1u PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Azotobacter
vinelandii) 		5 / 12 GLY A 129
ASN A   7
ASP A 154
ILE A 156
VAL A 126
 None
 1.10A 2hmyB-3t1uA:
undetectable		 2hmyB-3t1uA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LH6_A_NIOA155_1
(LEGHEMOGLOBIN A
(NICOTINATE MET))		 3t1u PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Azotobacter
vinelandii) 		4 / 5 PHE A  27
PHE A  98
PHE A  41
VAL A  31
 None
 1.21A 2lh6A-3t1uA:
undetectable		 2lh6A-3t1uA:
23.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A25_A_SAMA279_0
(UNCHARACTERIZED
PROTEIN PH0793)		 3t1u PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Azotobacter
vinelandii) 		5 / 12 PHE A  99
GLY A  52
HIS A  42
ILE A 100
ASN A 101
 None
 1.42A 3a25A-3t1uA:
undetectable		 3a25A-3t1uA:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E9X_A_NIMA1_1
(LACTOTRANSFERRIN')		 3t1u PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Azotobacter
vinelandii) 		4 / 4 GLU A 158
GLY A  38
THR A  39
GLU A  56
 None
 1.27A 3e9xA-3t1uA:
undetectable		 3e9xA-3t1uA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWX_B_EPAB3_2
(PROTEIN (PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
(PPAR-DELTA)))		 3t1u PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Azotobacter
vinelandii) 		5 / 12 GLN A  97
ILE A  68
VAL A  31
LEU A  13
ILE A  83
 None
 1.14A 3gwxB-3t1uA:
undetectable		 3gwxB-3t1uA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDV_B_CL6B506_1
(CHOLESTEROL
24-HYDROXYLASE)		 3t1u PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Azotobacter
vinelandii) 		5 / 12 THR A  82
ILE A  83
ALA A  84
ALA A  24
THR A  23
 None
 0.95A 3mdvB-3t1uA:
undetectable		 3mdvB-3t1uA:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_D_RTZD2_1
(CYTOCHROME P450 2D6)		 3t1u PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Azotobacter
vinelandii) 		5 / 9 PHE A  27
LEU A   4
THR A  10
LEU A  15
ILE A   2
 None
 1.19A 3tbgD-3t1uA:
undetectable		 3tbgD-3t1uA:
15.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_C_ADNC401_2
(ADENOSINE KINASE)		 3t1u PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Azotobacter
vinelandii) 		4 / 5 ASN A 105
LEU A 108
SER A  77
ASN A  74
 None
 1.18A 4n09C-3t1uA:
undetectable		 4n09C-3t1uA:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD4_C_AOQC4003_1
(CYTOCHROME B)		 3t1u PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Azotobacter
vinelandii) 		5 / 12 PHE A  98
GLY A  52
ILE A  40
LEU A   4
ILE A 162
 None
 1.10A 4pd4C-3t1uA:
undetectable		 4pd4C-3t1uA:
16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BRD_A_RFPA502_1
(RIFAMPIN
MONOOXYGENASE)		 3t1u PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Azotobacter
vinelandii) 		5 / 12 VAL A 139
LEU A  13
VAL A 126
THR A  10
GLY A   9
 None
 1.31A 6brdA-3t1uA:
undetectable		 6brdA-3t1uA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MHT_D_SAMD328_0
(CYTOSINE-SPECIFIC
METHYLTRANSFERASE
HHAI)		 3t1u PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Azotobacter
vinelandii) 		5 / 12 GLY A 129
ASN A   7
ASP A 154
ILE A 156
VAL A 126
 None
 1.02A 6mhtA-3t1uA:
undetectable		 6mhtA-3t1uA:
21.18