SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3t2x'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UZ2_A_ACTA1123_0
(XENAVIDIN)		 3t2x AVIDIN/STREPTAVIDIN
(Shewanella
denitrificans) 		4 / 7 ASN A  15
SER A  19
TYR A  36
TRP A  80
 None
 0.38A 2uz2A-3t2xA:
15.7		 2uz2A-3t2xA:
28.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_A_DVAA8_0
(GRAMICIDIN A)		 3t2x AVIDIN/STREPTAVIDIN
(Shewanella
denitrificans) 		3 / 3 VAL A 116
TRP A  80
TRP A  97
 None
 1.21A 2xdcA-3t2xA:
undetectable
2xdcB-3t2xA:
undetectable		 2xdcA-3t2xA:
12.94
2xdcB-3t2xA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_A_DVAA8_0
(GRAMICIDIN A)		 3t2x AVIDIN/STREPTAVIDIN
(Shewanella
denitrificans) 		3 / 3 VAL A 116
TRP A  97
TRP A  80
 None
 1.20A 2xdcA-3t2xA:
undetectable
2xdcB-3t2xA:
undetectable		 2xdcA-3t2xA:
12.94
2xdcB-3t2xA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_B_DVAB8_0
(GRAMICIDIN A)		 3t2x AVIDIN/STREPTAVIDIN
(Shewanella
denitrificans) 		3 / 3 TRP A  80
VAL A 116
TRP A  97
 None
 1.18A 2xdcA-3t2xA:
undetectable
2xdcB-3t2xA:
undetectable		 2xdcA-3t2xA:
12.94
2xdcB-3t2xA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_B_DVAB8_0
(GRAMICIDIN A)		 3t2x AVIDIN/STREPTAVIDIN
(Shewanella
denitrificans) 		3 / 3 TRP A  97
VAL A 116
TRP A  80
 None
 1.21A 2xdcA-3t2xA:
undetectable
2xdcB-3t2xA:
undetectable		 2xdcA-3t2xA:
12.94
2xdcB-3t2xA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_C_DVAC8_0
(GRAMICIDIN A)		 3t2x AVIDIN/STREPTAVIDIN
(Shewanella
denitrificans) 		3 / 3 VAL A 116
TRP A  80
TRP A  97
 None
 1.35A 2xdcC-3t2xA:
undetectable
2xdcD-3t2xA:
undetectable		 2xdcC-3t2xA:
12.94
2xdcD-3t2xA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_C_DVAC8_0
(GRAMICIDIN A)		 3t2x AVIDIN/STREPTAVIDIN
(Shewanella
denitrificans) 		3 / 3 VAL A 116
TRP A  97
TRP A  80
 None
 1.02A 2xdcC-3t2xA:
undetectable
2xdcD-3t2xA:
undetectable		 2xdcC-3t2xA:
12.94
2xdcD-3t2xA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y5M_A_DVAA8_0
(VAL-GRAMICIDIN A)		 3t2x AVIDIN/STREPTAVIDIN
(Shewanella
denitrificans) 		3 / 3 VAL A 116
TRP A  80
TRP A  97
 None
 1.21A 2y5mA-3t2xA:
undetectable
2y5mB-3t2xA:
undetectable		 2y5mA-3t2xA:
12.94
2y5mB-3t2xA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y5M_A_DVAA8_0
(VAL-GRAMICIDIN A)		 3t2x AVIDIN/STREPTAVIDIN
(Shewanella
denitrificans) 		3 / 3 VAL A 116
TRP A  97
TRP A  80
 None
 1.19A 2y5mA-3t2xA:
undetectable
2y5mB-3t2xA:
undetectable		 2y5mA-3t2xA:
12.94
2y5mB-3t2xA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_A_DVAA8_0
(VAL-GRAMICIDIN A)		 3t2x AVIDIN/STREPTAVIDIN
(Shewanella
denitrificans) 		3 / 3 VAL A 116
TRP A  80
TRP A  97
 None
 1.22A 2y6nA-3t2xA:
undetectable
2y6nB-3t2xA:
undetectable		 2y6nA-3t2xA:
12.94
2y6nB-3t2xA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_A_DVAA8_0
(VAL-GRAMICIDIN A)		 3t2x AVIDIN/STREPTAVIDIN
(Shewanella
denitrificans) 		3 / 3 VAL A 116
TRP A  97
TRP A  80
 None
 1.19A 2y6nA-3t2xA:
undetectable
2y6nB-3t2xA:
undetectable		 2y6nA-3t2xA:
12.94
2y6nB-3t2xA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_B_DVAB8_0
(VAL-GRAMICIDIN A)		 3t2x AVIDIN/STREPTAVIDIN
(Shewanella
denitrificans) 		3 / 3 TRP A  80
VAL A 116
TRP A  97
 None
 1.19A 2y6nA-3t2xA:
undetectable
2y6nB-3t2xA:
undetectable		 2y6nA-3t2xA:
12.94
2y6nB-3t2xA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_B_DVAB8_0
(VAL-GRAMICIDIN A)		 3t2x AVIDIN/STREPTAVIDIN
(Shewanella
denitrificans) 		3 / 3 TRP A  97
VAL A 116
TRP A  80
 None
 1.20A 2y6nA-3t2xA:
undetectable
2y6nB-3t2xA:
undetectable		 2y6nA-3t2xA:
12.94
2y6nB-3t2xA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A3B_A_RBFA191_1
(LUMAZINE PROTEIN)		 3t2x AVIDIN/STREPTAVIDIN
(Shewanella
denitrificans) 		5 / 12 LEU A   7
THR A   8
GLN A 119
ASN A  86
ILE A  85
 None
 1.21A 3a3bA-3t2xA:
undetectable		 3a3bA-3t2xA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQ8_A_DVAA8_0
(VAL-GRAMICIDIN A)		 3t2x AVIDIN/STREPTAVIDIN
(Shewanella
denitrificans) 		3 / 3 VAL A 116
TRP A  80
TRP A  97
 None
 1.24A 3zq8A-3t2xA:
undetectable
3zq8B-3t2xA:
undetectable		 3zq8A-3t2xA:
12.94
3zq8B-3t2xA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQ8_A_DVAA8_0
(VAL-GRAMICIDIN A)		 3t2x AVIDIN/STREPTAVIDIN
(Shewanella
denitrificans) 		3 / 3 VAL A 116
TRP A  97
TRP A  80
 None
 1.09A 3zq8A-3t2xA:
undetectable
3zq8B-3t2xA:
undetectable		 3zq8A-3t2xA:
12.94
3zq8B-3t2xA:
12.94