SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3t33'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXG_A_ACRA443_1
(ALPHA AMYLASE)		 3t33 G PROTEIN COUPLED
RECEPTOR
(Arabidopsis
thaliana) 		4 / 8 SER A 113
ASN A  74
ASP A  72
GLU A 385
 None
 1.18A 1mxgA-3t33A:
undetectable		 1mxgA-3t33A:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOH_C_FRDC305_1
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 3t33 G PROTEIN COUPLED
RECEPTOR
(Arabidopsis
thaliana) 		4 / 5 LEU A 149
ASP A 146
GLY A 140
ALA A 133
 None
 0.96A 2aohA-3t33A:
undetectable		 2aohA-3t33A:
15.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V3K_A_SAMA1254_0
(ESSENTIAL FOR
MITOTIC GROWTH 1)		 3t33 G PROTEIN COUPLED
RECEPTOR
(Arabidopsis
thaliana) 		5 / 10 LEU A  75
GLY A 124
GLY A  81
LEU A 383
SER A 382
 None
 1.00A 2v3kA-3t33A:
undetectable		 2v3kA-3t33A:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZM9_A_ACAA502_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 3t33 G PROTEIN COUPLED
RECEPTOR
(Arabidopsis
thaliana) 		4 / 8 MET A 390
ALA A 391
GLY A 388
ILE A 387
 None
 0.72A 2zm9A-3t33A:
undetectable		 2zm9A-3t33A:
23.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FPJ_B_SAMB301_1
(PUTATIVE
UNCHARACTERIZED
PROTEIN)		 3t33 G PROTEIN COUPLED
RECEPTOR
(Arabidopsis
thaliana) 		4 / 7 GLY A 204
GLY A 208
THR A 254
GLU A 199
 None
 0.85A 3fpjB-3t33A:
undetectable		 3fpjB-3t33A:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FPJ_B_SAMB301_1
(PUTATIVE
UNCHARACTERIZED
PROTEIN)		 3t33 G PROTEIN COUPLED
RECEPTOR
(Arabidopsis
thaliana) 		4 / 7 GLY A 226
GLY A 285
GLU A 164
ALA A 232
 None
 0.64A 3fpjB-3t33A:
undetectable		 3fpjB-3t33A:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGH_D_FLPD701_1
(CYCLOOXYGENASE-2)		 3t33 G PROTEIN COUPLED
RECEPTOR
(Arabidopsis
thaliana) 		5 / 12 VAL A  59
VAL A  79
GLY A  81
ALA A  83
LEU A  86
 None
 1.09A 3pghD-3t33A:
undetectable		 3pghD-3t33A:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PMZ_E_TUBE220_2
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 3t33 G PROTEIN COUPLED
RECEPTOR
(Arabidopsis
thaliana) 		4 / 7 TYR A 167
CYH A 283
CYH A 328
TYR A  76
 None
ZN  A 411 ( 2.2A)
ZN  A 411 ( 2.3A)
None
 1.48A 3pmzE-3t33A:
undetectable		 3pmzE-3t33A:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W68_C_VIVC301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 3t33 G PROTEIN COUPLED
RECEPTOR
(Arabidopsis
thaliana) 		5 / 12 LEU A 165
VAL A 196
VAL A 237
LEU A 238
VAL A 197
 None
 1.26A 3w68C-3t33A:
undetectable		 3w68C-3t33A:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CP3_B_RBTB1129_1
(B-CELL LYMPHOMA 6
PROTEIN)		 3t33 G PROTEIN COUPLED
RECEPTOR
(Arabidopsis
thaliana) 		4 / 7 ARG A 151
GLY A 124
TYR A 125
SER A 116
 None
 0.96A 4cp3A-3t33A:
undetectable
4cp3B-3t33A:
undetectable		 4cp3A-3t33A:
16.48
4cp3B-3t33A:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L6V_1_PQN12001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
FUSION PROTEIN OF
PHOTOSYSTEM I
SUBUNIT III AND
SUBUNIT IX)		 3t33 G PROTEIN COUPLED
RECEPTOR
(Arabidopsis
thaliana) 		5 / 11 SER A 332
GLY A 326
LEU A 383
GLY A 388
ALA A 133
 None
 1.18A 4l6v1-3t33A:
undetectable
4l6v6-3t33A:
undetectable		 4l6v1-3t33A:
20.13
4l6v6-3t33A:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB307_1
(CHITOSANASE)		 3t33 G PROTEIN COUPLED
RECEPTOR
(Arabidopsis
thaliana) 		4 / 7 GLU A 164
ARG A 118
THR A 120
GLY A 168
 None
 0.82A 4qwpB-3t33A:
undetectable		 4qwpB-3t33A:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRX_A_LURA706_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3t33 G PROTEIN COUPLED
RECEPTOR
(Arabidopsis
thaliana) 		5 / 12 VAL A  59
VAL A  79
GLY A  81
ALA A  83
LEU A  86
 None
 1.11A 4rrxA-3t33A:
undetectable		 4rrxA-3t33A:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRX_B_LURB706_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3t33 G PROTEIN COUPLED
RECEPTOR
(Arabidopsis
thaliana) 		5 / 12 VAL A  59
VAL A  79
GLY A  81
ALA A  83
LEU A  86
 None
 1.12A 4rrxB-3t33A:
undetectable		 4rrxB-3t33A:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTB_A_SAMA501_1
(HYDG PROTEIN)		 3t33 G PROTEIN COUPLED
RECEPTOR
(Arabidopsis
thaliana) 		3 / 3 GLU A 199
ARG A 169
GLN A 206
 None
 0.82A 4rtbA-3t33A:
undetectable		 4rtbA-3t33A:
23.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP4_A_COCA706_1
(DOPAMINE TRANSPORTER)		 3t33 G PROTEIN COUPLED
RECEPTOR
(Arabidopsis
thaliana) 		5 / 11 ASP A 396
ALA A 403
TYR A  84
GLY A 333
GLY A 388
 None
 1.22A 4xp4A-3t33A:
undetectable		 4xp4A-3t33A:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZB_E_ACTE403_0
(PROTON-GATED ION
CHANNEL)		 3t33 G PROTEIN COUPLED
RECEPTOR
(Arabidopsis
thaliana) 		3 / 3 ARG A 202
TYR A 163
GLU A 199
 None
 0.68A 4zzbE-3t33A:
2.6		 4zzbE-3t33A:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZC_A_ACTA406_0
(PROTON-GATED ION
CHANNEL)		 3t33 G PROTEIN COUPLED
RECEPTOR
(Arabidopsis
thaliana) 		4 / 4 LEU A 157
ILE A 155
ARG A 192
TYR A 172
 None
 1.30A 4zzcA-3t33A:
3.1		 4zzcA-3t33A:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZC_B_ACTB406_0
(PROTON-GATED ION
CHANNEL)		 3t33 G PROTEIN COUPLED
RECEPTOR
(Arabidopsis
thaliana) 		4 / 4 LEU A 157
ILE A 155
ARG A 192
TYR A 172
 None
 1.32A 4zzcB-3t33A:
3.1		 4zzcB-3t33A:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_A_SORA1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3t33 G PROTEIN COUPLED
RECEPTOR
(Arabidopsis
thaliana) 		4 / 7 ILE A 327
LEU A 383
GLY A 388
GLY A 389
 None
 0.75A 5a06A-3t33A:
undetectable		 5a06A-3t33A:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_B_SORB1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3t33 G PROTEIN COUPLED
RECEPTOR
(Arabidopsis
thaliana) 		4 / 7 ILE A 327
LEU A 383
GLY A 388
GLY A 389
 None
 0.76A 5a06B-3t33A:
undetectable		 5a06B-3t33A:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_C_SORC1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3t33 G PROTEIN COUPLED
RECEPTOR
(Arabidopsis
thaliana) 		4 / 7 ILE A 327
LEU A 383
GLY A 388
GLY A 389
 None
 0.76A 5a06C-3t33A:
undetectable		 5a06C-3t33A:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_E_SORE1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3t33 G PROTEIN COUPLED
RECEPTOR
(Arabidopsis
thaliana) 		4 / 7 ILE A 327
LEU A 383
GLY A 388
GLY A 389
 None
 0.77A 5a06E-3t33A:
undetectable		 5a06E-3t33A:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_F_SORF1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3t33 G PROTEIN COUPLED
RECEPTOR
(Arabidopsis
thaliana) 		4 / 7 ILE A 327
LEU A 383
GLY A 388
GLY A 389
 None
 0.75A 5a06F-3t33A:
undetectable		 5a06F-3t33A:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDP_H_EVPH2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B)		 3t33 G PROTEIN COUPLED
RECEPTOR
(Arabidopsis
thaliana) 		4 / 6 SER A 256
GLY A 204
ARG A 205
GLY A 208
 None
 0.98A 5cdpA-3t33A:
undetectable
5cdpB-3t33A:
undetectable		 5cdpA-3t33A:
23.17
5cdpB-3t33A:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DSG_B_0HKB1201_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)		 3t33 G PROTEIN COUPLED
RECEPTOR
(Arabidopsis
thaliana) 		3 / 3 ASP A 110
ASN A 105
PHE A  87
 None
 0.63A 5dsgB-3t33A:
undetectable		 5dsgB-3t33A:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F1A_A_SALA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3t33 G PROTEIN COUPLED
RECEPTOR
(Arabidopsis
thaliana) 		4 / 8 LEU A  80
TYR A  73
GLY A 127
ALA A 126
 None
 0.71A 5f1aA-3t33A:
undetectable		 5f1aA-3t33A:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F1A_B_SALB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3t33 G PROTEIN COUPLED
RECEPTOR
(Arabidopsis
thaliana) 		4 / 7 LEU A  80
TYR A  73
GLY A 127
ALA A 126
 None
 0.80A 5f1aB-3t33A:
undetectable		 5f1aB-3t33A:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NKN_A_LOCA201_2
(NEUTROPHIL
GELATINASE-ASSOCIATE
D LIPOCALIN)		 3t33 G PROTEIN COUPLED
RECEPTOR
(Arabidopsis
thaliana) 		3 / 3 VAL A 280
LYS A 323
MET A 374
 None
 1.03A 5nknA-3t33A:
undetectable		 5nknA-3t33A:
10.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_D_AQ4D602_0
(CYTOCHROME P450 1A1)		 3t33 G PROTEIN COUPLED
RECEPTOR
(Arabidopsis
thaliana) 		5 / 12 ILE A 327
PHE A 405
GLY A 288
ALA A 227
ILE A 122
 None
 1.09A 6dwnD-3t33A:
undetectable		 6dwnD-3t33A:
11.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_B_DAHB123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3t33 G PROTEIN COUPLED
RECEPTOR
(Arabidopsis
thaliana) 		5 / 10 PHE A 384
LEU A  75
GLY A 389
ILE A 327
PHE A 121
 None
 1.26A 6ebpB-3t33A:
undetectable		 6ebpB-3t33A:
12.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_C_DAHC123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3t33 G PROTEIN COUPLED
RECEPTOR
(Arabidopsis
thaliana) 		5 / 10 PHE A 384
LEU A  75
GLY A 389
ILE A 327
PHE A 121
 None
 1.19A 6ebpC-3t33A:
undetectable		 6ebpC-3t33A:
12.53