SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3t36'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BDW_B_DVAB6_0
(GRAMICIDIN A)		 3t36 ENDO-TYPE
MEMBRANE-BOUND LYTIC
MUREIN
TRANSGLYCOSYLASE A
(Escherichia
coli) 		3 / 3 TRP A  50
ALA A  48
VAL A  52
 None
 0.86A 1bdwA-3t36A:
undetectable
1bdwB-3t36A:
undetectable		 1bdwA-3t36A:
9.01
1bdwB-3t36A:
9.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RBP_A_RTLA183_0
(PLASMA
RETINOL-BINDING
PROTEIN PRECURSOR)		 3t36 ENDO-TYPE
MEMBRANE-BOUND LYTIC
MUREIN
TRANSGLYCOSYLASE A
(Escherichia
coli) 		5 / 12 ALA A  29
ALA A 202
ALA A 199
VAL A 143
LEU A  56
 None
 1.20A 1rbpA-3t36A:
undetectable		 1rbpA-3t36A:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O5Y_H_STRH249_1
(CHIMERIC ANTIBODY
FAB 1E9-DB3)		 3t36 ENDO-TYPE
MEMBRANE-BOUND LYTIC
MUREIN
TRANSGLYCOSYLASE A
(Escherichia
coli) 		4 / 7 ASN A 113
GLY A  79
MET A  81
SER A  88
 None
 1.09A 2o5yH-3t36A:
undetectable
2o5yL-3t36A:
undetectable		 2o5yH-3t36A:
22.31
2o5yL-3t36A:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB152_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3t36 ENDO-TYPE
MEMBRANE-BOUND LYTIC
MUREIN
TRANSGLYCOSYLASE A
(Escherichia
coli) 		3 / 3 ASN A 183
HIS A 184
VAL A 144
 None
 0.82A 3elzB-3t36A:
undetectable		 3elzB-3t36A:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J26_A_ESTA600_1
(ESTROGEN RECEPTOR
BETA)		 3t36 ENDO-TYPE
MEMBRANE-BOUND LYTIC
MUREIN
TRANSGLYCOSYLASE A
(Escherichia
coli) 		5 / 12 LEU A 138
GLU A 125
LEU A 121
GLY A 149
LEU A 153
 None
 1.27A 4j26A-3t36A:
undetectable		 4j26A-3t36A:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_C_ADNC501_2
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 3t36 ENDO-TYPE
MEMBRANE-BOUND LYTIC
MUREIN
TRANSGLYCOSYLASE A
(Escherichia
coli) 		3 / 3 PRO A 187
VAL A 180
HIS A 179
 None
 0.82A 4pevC-3t36A:
undetectable		 4pevC-3t36A:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZGF_A_BEZA210_0
(UNCHARACTERIZED
PROTEIN)		 3t36 ENDO-TYPE
MEMBRANE-BOUND LYTIC
MUREIN
TRANSGLYCOSYLASE A
(Escherichia
coli) 		4 / 4 VAL A  33
ALA A  29
ASN A  28
GLN A 198
 None
 1.15A 4zgfA-3t36A:
undetectable		 4zgfA-3t36A:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBF_A_ACTA507_0
(MOLYBDOPTERIN
BIOSYNTHESIS PROTEIN
CNX1)		 3t36 ENDO-TYPE
MEMBRANE-BOUND LYTIC
MUREIN
TRANSGLYCOSYLASE A
(Escherichia
coli) 		3 / 3 LYS A  84
SER A  73
SER A  75
 None
 1.15A 6gbfA-3t36A:
undetectable		 6gbfA-3t36A:
20.28