SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3t38'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GL0_C_ADNC903_1
(CONSERVED
HYPOTHETICAL PROTEIN)		 3t38 ARSENATE REDUCTASE
(Corynebacterium
glutamicum) 		5 / 12 ILE A 194
ALA A  92
ASN A  91
VAL A 136
SER A 114
 None
 1.28A 2gl0A-3t38A:
undetectable
2gl0C-3t38A:
undetectable		 2gl0A-3t38A:
23.61
2gl0C-3t38A:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GL0_D_ADND904_1
(CONSERVED
HYPOTHETICAL PROTEIN)		 3t38 ARSENATE REDUCTASE
(Corynebacterium
glutamicum) 		5 / 12 SER A 114
ILE A 194
ALA A  92
ASN A  91
VAL A 136
 None
 1.28A 2gl0D-3t38A:
undetectable
2gl0E-3t38A:
undetectable		 2gl0D-3t38A:
23.61
2gl0E-3t38A:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_D_CELD682_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3t38 ARSENATE REDUCTASE
(Corynebacterium
glutamicum) 		4 / 5 ARG A  47
LEU A  55
ARG A  66
ILE A  38
 None
None
D1D  A3236 (-3.3A)
None
 1.19A 3ln1D-3t38A:
undetectable		 3ln1D-3t38A:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3t38 ARSENATE REDUCTASE
(Corynebacterium
glutamicum) 		4 / 6 ILE A 201
LEU A 102
ARG A  94
THR A 159
 None
 0.94A 3wg7A-3t38A:
2.6
3wg7J-3t38A:
undetectable		 3wg7A-3t38A:
17.34
3wg7J-3t38A:
16.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I89_A_1FLA201_1
(TRANSTHYRETIN)		 3t38 ARSENATE REDUCTASE
(Corynebacterium
glutamicum) 		4 / 6 LEU A  58
ALA A  49
SER A  44
THR A  48
 None
 0.92A 4i89A-3t38A:
undetectable		 4i89A-3t38A:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2X_C_TMQC202_1
(DIHYDROFOLATE
REDUCTASE)		 3t38 ARSENATE REDUCTASE
(Corynebacterium
glutamicum) 		5 / 12 ILE A 190
GLN A  96
LEU A 101
LEU A 131
ILE A 194
 None
 0.95A 4m2xC-3t38A:
undetectable		 4m2xC-3t38A:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BOJ_A_4TXA201_1
(TRANSTHYRETIN)		 3t38 ARSENATE REDUCTASE
(Corynebacterium
glutamicum) 		4 / 6 LEU A  58
ALA A  49
SER A  44
THR A  48
 None
 0.89A 5bojA-3t38A:
undetectable		 5bojA-3t38A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L4I_A_6J3A201_0
(TRANSTHYRETIN)		 3t38 ARSENATE REDUCTASE
(Corynebacterium
glutamicum) 		4 / 6 LEU A  58
ALA A  49
SER A  44
THR A  48
 None
 0.90A 5l4iA-3t38A:
undetectable		 5l4iA-3t38A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DRY_A_H8DA2001_0
(5HT2B RECEPTOR, BRIL
CHIMERA)		 3t38 ARSENATE REDUCTASE
(Corynebacterium
glutamicum) 		5 / 11 ASP A 149
VAL A 150
LEU A 146
PHE A  62
TYR A  37
 None
None
None
None
D1D  A3236 (-3.6A)
 1.08A 6dryA-3t38A:
undetectable		 6dryA-3t38A:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_C_AQ4C602_1
(CYTOCHROME P450 1A1)		 3t38 ARSENATE REDUCTASE
(Corynebacterium
glutamicum) 		3 / 3 SER A 114
SER A  95
ALA A 120
 None
 0.67A 6dwnC-3t38A:
undetectable		 6dwnC-3t38A:
15.61