SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3t3a'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ITZ_A_IREA2021_2
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 3t3a KILLER CELL
LECTIN-LIKE RECEPTOR
SUBFAMILY B MEMBER
1A
(Mus
musculus) 		3 / 3 LEU A 214
LEU A 131
MET A 130
 None
 0.80A 2itzA-3t3aA:
undetectable		 2itzA-3t3aA:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KF9_A_ACTA407_0
(GLUTATHIONE
S-TRANSFERASE
PROTEIN)		 3t3a KILLER CELL
LECTIN-LIKE RECEPTOR
SUBFAMILY B MEMBER
1A
(Mus
musculus) 		3 / 3 GLU A 136
ARG A 102
HIS A 101
 None
 0.78A 4kf9A-3t3aA:
undetectable		 4kf9A-3t3aA:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODI_G_ACTG702_0
(HETERODISULFIDE
REDUCTASE, SUBUNIT A)		 3t3a KILLER CELL
LECTIN-LIKE RECEPTOR
SUBFAMILY B MEMBER
1A
(Mus
musculus) 		3 / 3 GLY A 182
THR A 184
ASN A 203
 None
 0.69A 5odiG-3t3aA:
undetectable		 5odiG-3t3aA:
12.57