SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3t4r'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OHT_A_1N1A2000_1 (P38A)	3t4r	PHOSPHOPROTEIN (Lettuce necrotic yellows cytorhabdovirus)	5 / 12	ASP A 37 VAL A 30 ILE A 22 ILE A 54 ALA A 40	None	1.19A	3ohtA-3t4rA: undetectable 3ohtB-3t4rA: undetectable	3ohtA-3t4rA: 11.20 3ohtB-3t4rA: 11.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4K4Y_A_ACTA502_0 (RNA-DEPENDENT RNA POLYMERASE)	3t4r	PHOSPHOPROTEIN (Lettuce necrotic yellows cytorhabdovirus)	4 / 5	LYS A 10 LEU A 11 GLU A 7 LEU A 39	None	1.38A	4k4yA-3t4rA: undetectable	4k4yA-3t4rA: 11.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4K4Y_E_ACTE503_0 (RNA-DEPENDENT RNA POLYMERASE)	3t4r	PHOSPHOPROTEIN (Lettuce necrotic yellows cytorhabdovirus)	4 / 4	LYS A 10 LEU A 11 GLU A 7 LEU A 39	None	1.40A	4k4yE-3t4rA: undetectable	4k4yE-3t4rA: 11.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PEV_B_ADNB501_2 (MEMBRANE LIPOPROTEIN FAMILY PROTEIN)	3t4r	PHOSPHOPROTEIN (Lettuce necrotic yellows cytorhabdovirus)	3 / 3	PRO A 48 LEU A 46 GLN A 55	None	0.68A	4pevB-3t4rA: undetectable	4pevB-3t4rA: 10.59

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3OHT_A_1N1A2000_1","P38A;P38A","3t4r","PHOSPHOPROTEIN","Lettuce necrotic yellows cytorhabdovirus",5,"ASP A  37;VAL A  30;ILE A  22;ILE A  54;ALA A  40","None","1.19A","3ohtA-3t4rA:undetectable;3ohtB-3t4rA:undetectable","3ohtA-3t4rA:11.20;3ohtB-3t4rA:11.20"],["4K4Y_A_ACTA502_0","RNA-DEPENDENT RNA POLYMERASE","3t4r","PHOSPHOPROTEIN","Lettuce necrotic yellows cytorhabdovirus",4,"LYS A  10;LEU A  11;GLU A   7;LEU A  39","None","1.38A","4k4yA-3t4rA:undetectable","4k4yA-3t4rA:11.02"],["4K4Y_E_ACTE503_0","RNA-DEPENDENT RNA POLYMERASE","3t4r","PHOSPHOPROTEIN","Lettuce necrotic yellows cytorhabdovirus",4,"LYS A  10;LEU A  11;GLU A   7;LEU A  39","None","1.40A","4k4yE-3t4rA:undetectable","4k4yE-3t4rA:11.02"],["4PEV_B_ADNB501_2","MEMBRANE LIPOPROTEIN FAMILY PROTEIN","3t4r","PHOSPHOPROTEIN","Lettuce necrotic yellows cytorhabdovirus",3,"PRO A  48;LEU A  46;GLN A  55","None","0.68A","4pevB-3t4rA:undetectable","4pevB-3t4rA:10.59"]]