SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3t57'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WG8_A_SAMA3142_0
(PREDICTED
S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 3t57 UDP-N-ACETYLGLUCOSAM
INE
O-ACYLTRANSFERASE
DOMAIN-CONTAINING
PROTEIN
(Arabidopsis
thaliana) 		5 / 12 PRO A 106
GLY A 135
ASP A 129
SER A 158
HIS A 180
 None
 1.19A 1wg8A-3t57A:
undetectable		 1wg8A-3t57A:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GJ5_A_VD3A163_1
(BETA-LACTOGLOBULIN)		 3t57 UDP-N-ACETYLGLUCOSAM
INE
O-ACYLTRANSFERASE
DOMAIN-CONTAINING
PROTEIN
(Arabidopsis
thaliana) 		5 / 12 LEU A  89
LEU A 140
ILE A 154
ILE A 148
ALA A 121
 None
 1.24A 2gj5A-3t57A:
undetectable		 2gj5A-3t57A:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_B_SALB1305_1
(LYSR-TYPE REGULATORY
PROTEIN)		 3t57 UDP-N-ACETYLGLUCOSAM
INE
O-ACYLTRANSFERASE
DOMAIN-CONTAINING
PROTEIN
(Arabidopsis
thaliana) 		4 / 5 SER A 157
ARG A 156
PRO A 106
GLY A 107
 None
 1.15A 2y7kB-3t57A:
undetectable		 2y7kB-3t57A:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7P_A_SALA1001_1
(LYSR-TYPE REGULATORY
PROTEIN)		 3t57 UDP-N-ACETYLGLUCOSAM
INE
O-ACYLTRANSFERASE
DOMAIN-CONTAINING
PROTEIN
(Arabidopsis
thaliana) 		4 / 6 SER A 157
ARG A 156
PRO A 106
GLY A 107
 None
 1.09A 2y7pA-3t57A:
undetectable		 2y7pA-3t57A:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B0W_B_DGXB1_2
(NUCLEAR RECEPTOR
ROR-GAMMA)		 3t57 UDP-N-ACETYLGLUCOSAM
INE
O-ACYLTRANSFERASE
DOMAIN-CONTAINING
PROTEIN
(Arabidopsis
thaliana) 		3 / 3 LEU A 105
VAL A 122
ARG A 156
 None
 0.64A 3b0wB-3t57A:
undetectable		 3b0wB-3t57A:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DH0_A_SAMA220_0
(SAM DEPENDENT
METHYLTRANSFERASE)		 3t57 UDP-N-ACETYLGLUCOSAM
INE
O-ACYLTRANSFERASE
DOMAIN-CONTAINING
PROTEIN
(Arabidopsis
thaliana) 		5 / 12 GLY A 229
VAL A 232
ALA A 191
THR A 194
LEU A 196
 None
 1.17A 3dh0A-3t57A:
undetectable		 3dh0A-3t57A:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DH0_B_SAMB300_0
(SAM DEPENDENT
METHYLTRANSFERASE)		 3t57 UDP-N-ACETYLGLUCOSAM
INE
O-ACYLTRANSFERASE
DOMAIN-CONTAINING
PROTEIN
(Arabidopsis
thaliana) 		5 / 12 GLY A 228
VAL A 232
ALA A 191
THR A 194
LEU A 196
 None
 0.97A 3dh0B-3t57A:
undetectable		 3dh0B-3t57A:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_I_SAMI300_0
(PUTATIVE RRNA
METHYLASE)		 3t57 UDP-N-ACETYLGLUCOSAM
INE
O-ACYLTRANSFERASE
DOMAIN-CONTAINING
PROTEIN
(Arabidopsis
thaliana) 		5 / 12 GLY A 143
ASN A 144
ASN A 145
GLY A 124
ASN A 170
 None
 1.18A 3eeyI-3t57A:
undetectable		 3eeyI-3t57A:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FPJ_A_SAMA301_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN)		 3t57 UDP-N-ACETYLGLUCOSAM
INE
O-ACYLTRANSFERASE
DOMAIN-CONTAINING
PROTEIN
(Arabidopsis
thaliana) 		5 / 12 PHE A 225
ILE A 226
GLY A 227
VAL A 242
ALA A 209
 None
 0.69A 3fpjA-3t57A:
undetectable		 3fpjA-3t57A:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_D_MIYD392_1
(TETX2 PROTEIN)		 3t57 UDP-N-ACETYLGLUCOSAM
INE
O-ACYLTRANSFERASE
DOMAIN-CONTAINING
PROTEIN
(Arabidopsis
thaliana) 		4 / 5 HIS A 177
SER A 153
GLN A 128
VAL A 122
 None
 0.88A 4a99D-3t57A:
undetectable		 4a99D-3t57A:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DTA_A_ADNA401_1
(APH(2'')-ID)		 3t57 UDP-N-ACETYLGLUCOSAM
INE
O-ACYLTRANSFERASE
DOMAIN-CONTAINING
PROTEIN
(Arabidopsis
thaliana) 		5 / 10 ILE A 184
ILE A 142
HIS A 155
LEU A 140
ILE A 154
 None
 1.31A 4dtaA-3t57A:
undetectable		 4dtaA-3t57A:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_I_ACTI507_0
(RNA POLYMERASE
3D-POL)		 3t57 UDP-N-ACETYLGLUCOSAM
INE
O-ACYLTRANSFERASE
DOMAIN-CONTAINING
PROTEIN
(Arabidopsis
thaliana) 		3 / 3 LYS A 159
PRO A 160
SER A 161
 None
 0.44A 4k50I-3t57A:
2.3		 4k50I-3t57A:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1X_A_017A101_2
(ASPARTYL PROTEASE)		 3t57 UDP-N-ACETYLGLUCOSAM
INE
O-ACYLTRANSFERASE
DOMAIN-CONTAINING
PROTEIN
(Arabidopsis
thaliana) 		5 / 12 LEU A 196
ILE A 154
ILE A 142
GLY A 167
ILE A 178
 None
 0.89A 4q1xB-3t57A:
undetectable		 4q1xB-3t57A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB304_1
(CHITOSANASE)		 3t57 UDP-N-ACETYLGLUCOSAM
INE
O-ACYLTRANSFERASE
DOMAIN-CONTAINING
PROTEIN
(Arabidopsis
thaliana) 		3 / 3 GLN A 216
SER A 158
ASP A 129
 None
 0.96A 4qwpA-3t57A:
undetectable
4qwpB-3t57A:
undetectable		 4qwpA-3t57A:
18.30
4qwpB-3t57A:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U9U_A_ACTA1502_0
(NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT F)		 3t57 UDP-N-ACETYLGLUCOSAM
INE
O-ACYLTRANSFERASE
DOMAIN-CONTAINING
PROTEIN
(Arabidopsis
thaliana) 		4 / 5 ARG A 250
GLY A 244
ALA A 247
GLY A 227
 None
 0.94A 4u9uA-3t57A:
undetectable		 4u9uA-3t57A:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U9U_B_ACTB1502_0
(NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT F)		 3t57 UDP-N-ACETYLGLUCOSAM
INE
O-ACYLTRANSFERASE
DOMAIN-CONTAINING
PROTEIN
(Arabidopsis
thaliana) 		4 / 5 ARG A 250
GLY A 244
ALA A 247
GLY A 227
 None
 0.88A 4u9uB-3t57A:
undetectable		 4u9uB-3t57A:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HGC_A_HCYA501_1
(SERPIN)		 3t57 UDP-N-ACETYLGLUCOSAM
INE
O-ACYLTRANSFERASE
DOMAIN-CONTAINING
PROTEIN
(Arabidopsis
thaliana) 		5 / 12 VAL A 236
PRO A 237
ALA A 224
THR A 194
PHE A 190
 None
 1.41A 5hgcA-3t57A:
undetectable		 5hgcA-3t57A:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_A_P06A801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 3t57 UDP-N-ACETYLGLUCOSAM
INE
O-ACYLTRANSFERASE
DOMAIN-CONTAINING
PROTEIN
(Arabidopsis
thaliana) 		4 / 7 ILE A  65
GLY A  66
CYH A  75
PHE A 110
 None
 0.95A 5hieA-3t57A:
undetectable		 5hieA-3t57A:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TJY_A_BEZA304_0
(4-HYDROXY-TETRAHYDRO
DIPICOLINATE
REDUCTASE)		 3t57 UDP-N-ACETYLGLUCOSAM
INE
O-ACYLTRANSFERASE
DOMAIN-CONTAINING
PROTEIN
(Arabidopsis
thaliana) 		3 / 3 MET A 267
GLU A 255
ARG A 258
 None
 0.93A 5tjyA-3t57A:
undetectable		 5tjyA-3t57A:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TJZ_A_BEZA302_0
(4-HYDROXY-TETRAHYDRO
DIPICOLINATE
REDUCTASE)		 3t57 UDP-N-ACETYLGLUCOSAM
INE
O-ACYLTRANSFERASE
DOMAIN-CONTAINING
PROTEIN
(Arabidopsis
thaliana) 		3 / 3 MET A 267
GLU A 255
ARG A 258
 None
 0.96A 5tjzA-3t57A:
undetectable		 5tjzA-3t57A:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_D_AM2D301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 3t57 UDP-N-ACETYLGLUCOSAM
INE
O-ACYLTRANSFERASE
DOMAIN-CONTAINING
PROTEIN
(Arabidopsis
thaliana) 		4 / 8 ASP A 129
HIS A 134
HIS A 180
ASP A 136
 None
 1.20A 6mn4D-3t57A:
undetectable		 6mn4D-3t57A:
23.33