SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3t58'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		 3t58 SULFHYDRYL OXIDASE 1
(Mus
musculus) 		5 / 12 ALA A 188
PHE A 183
PHE A 182
LEU A 242
LEU A 272
 None
 1.09A 1dtlA-3t58A:
undetectable		 1dtlA-3t58A:
14.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FE2_A_LAXA700_2
(PROSTAGLANDIN
ENDOPEROXIDE H
SYNTHASE-1)		 3t58 SULFHYDRYL OXIDASE 1
(Mus
musculus) 		5 / 12 PHE A 406
LEU A 333
PHE A 374
GLY A 320
GLY A 451
 None
 1.11A 1fe2A-3t58A:
0.1		 1fe2A-3t58A:
19.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K5Q_B_PACB559_0
(PENICILLIN G ACYLASE
ALPHA SUBUNIT
PENICILLIN G ACYLASE
BETA SUBUNIT)		 3t58 SULFHYDRYL OXIDASE 1
(Mus
musculus) 		4 / 7 SER A 425
ALA A 421
TYR A 343
ALA A 433
 None
 1.03A 1k5qA-3t58A:
undetectable
1k5qB-3t58A:
undetectable		 1k5qA-3t58A:
17.73
1k5qB-3t58A:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TKQ_B_DVAB6_0
(GRAMICIDIN A)		 3t58 SULFHYDRYL OXIDASE 1
(Mus
musculus) 		3 / 3 ALA A 489
VAL A 504
TRP A 506
 None
None
FAD  A 601 (-3.7A)
 0.68A 1tkqB-3t58A:
undetectable		 1tkqB-3t58A:
3.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN5_A_FUNA1356_1
(THYROXINE-BINDING
GLOBULIN)		 3t58 SULFHYDRYL OXIDASE 1
(Mus
musculus) 		5 / 11 ALA A 137
LEU A  97
LEU A 153
LEU A 139
LEU A  86
 None
 1.06A 2xn5A-3t58A:
undetectable		 2xn5A-3t58A:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MEC_A_65BA561_0
(P66 REVERSE
TRANSCRIPTASE)		 3t58 SULFHYDRYL OXIDASE 1
(Mus
musculus) 		5 / 12 LEU A 311
VAL A 350
GLY A 346
PHE A 416
LEU A 413
 None
 1.25A 3mecA-3t58A:
undetectable		 3mecA-3t58A:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MED_A_65BA561_0
(P51 REVERSE
TRANSCRIPTASE
P66 REVERSE
TRANSCRIPTASE)		 3t58 SULFHYDRYL OXIDASE 1
(Mus
musculus) 		5 / 12 LEU A 311
VAL A 350
GLY A 346
PHE A 416
LEU A 413
 None
 1.26A 3medA-3t58A:
undetectable
3medB-3t58A:
undetectable		 3medA-3t58A:
21.64
3medB-3t58A:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9C_A_ECLA451_1
(CYTOCHROME P450
164A2)		 3t58 SULFHYDRYL OXIDASE 1
(Mus
musculus) 		5 / 10 ALA A 156
LEU A  97
LEU A 208
ALA A 167
VAL A 218
 None
 1.42A 3r9cA-3t58A:
undetectable		 3r9cA-3t58A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNI_A_SALA1344_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3t58 SULFHYDRYL OXIDASE 1
(Mus
musculus) 		4 / 7 GLU A 115
THR A  56
VAL A  57
LEU A  58
 None
 0.97A 3uniA-3t58A:
undetectable		 3uniA-3t58A:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A83_A_DXCA1161_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 3t58 SULFHYDRYL OXIDASE 1
(Mus
musculus) 		5 / 12 GLY A 398
PHE A 501
VAL A 412
ASP A 306
TYR A 303
 None
None
FAD  A 601 ( 4.8A)
None
None
 1.24A 4a83A-3t58A:
undetectable		 4a83A-3t58A:
14.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWL_B_ASCB304_0
(DIOSCORIN 5)		 3t58 SULFHYDRYL OXIDASE 1
(Mus
musculus) 		5 / 10 HIS A 516
PHE A 534
THR A 531
ALA A 530
TRP A 481
 None
 1.48A 4twlB-3t58A:
undetectable		 4twlB-3t58A:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_G_CHDG103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 3t58 SULFHYDRYL OXIDASE 1
(Mus
musculus) 		6 / 11 LEU A  86
GLU A 205
LEU A 153
LEU A  97
ARG A  94
LEU A  99
 None
 1.49A 4wg0E-3t58A:
undetectable
4wg0F-3t58A:
undetectable
4wg0G-3t58A:
undetectable		 4wg0E-3t58A:
4.85
4wg0F-3t58A:
4.85
4wg0G-3t58A:
4.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZOW_A_CLMA500_0
(MULTIDRUG
TRANSPORTER MDFA)		 3t58 SULFHYDRYL OXIDASE 1
(Mus
musculus) 		5 / 11 TYR A 445
LEU A 413
LEU A 410
LEU A 340
LEU A 361
 None
None
FAD  A 601 ( 4.1A)
None
None
 0.90A 4zowA-3t58A:
undetectable		 4zowA-3t58A:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E3I_B_HISB502_0
(HISTIDINE--TRNA
LIGASE)		 3t58 SULFHYDRYL OXIDASE 1
(Mus
musculus) 		5 / 11 GLU A 437
GLU A 431
TYR A 343
TYR A 424
ALA A 433
 None
 1.26A 5e3iB-3t58A:
2.5		 5e3iB-3t58A:
24.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M0O_A_EPAA502_1
(TERMINAL
OLEFIN-FORMING FATTY
ACID DECARBOXYLASE)		 3t58 SULFHYDRYL OXIDASE 1
(Mus
musculus) 		5 / 10 PHE A 195
ARG A 220
PRO A 173
ALA A 174
VAL A 229
 None
 0.91A 5m0oA-3t58A:
undetectable		 5m0oA-3t58A:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M0O_C_EPAC502_1
(TERMINAL
OLEFIN-FORMING FATTY
ACID DECARBOXYLASE)		 3t58 SULFHYDRYL OXIDASE 1
(Mus
musculus) 		4 / 8 PHE A 195
ARG A 220
PRO A 173
ALA A 174
 None
 0.82A 5m0oC-3t58A:
undetectable		 5m0oC-3t58A:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_A_CVIA301_0
(REGULATORY PROTEIN
TETR)		 3t58 SULFHYDRYL OXIDASE 1
(Mus
musculus) 		5 / 12 ALA A 341
GLU A 383
LEU A 311
ILE A 314
PHE A 374
 None
 1.29A 5vlmA-3t58A:
undetectable		 5vlmA-3t58A:
16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_E_CVIE301_0
(REGULATORY PROTEIN
TETR)		 3t58 SULFHYDRYL OXIDASE 1
(Mus
musculus) 		5 / 12 ALA A 341
GLU A 383
LEU A 311
ILE A 314
PHE A 374
 None
 1.11A 5vlmE-3t58A:
1.9		 5vlmE-3t58A:
16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A7P_A_9SCA601_1
(SERUM ALBUMIN)		 3t58 SULFHYDRYL OXIDASE 1
(Mus
musculus) 		4 / 5 ASN A 246
VAL A 216
LEU A 266
SER A 250
 None
 1.19A 6a7pA-3t58A:
undetectable		 6a7pA-3t58A:
23.70