SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3t61'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDU_D_ESTD352_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE)		 3t61 GLUCONOKINASE
(Sinorhizobium
meliloti) 		4 / 6 SER A  90
VAL A  89
LEU A  50
GLU A  79
 None
 1.03A 1fduD-3t61A:
4.2		 1fduD-3t61A:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_A_CHDA702_0
(FERROCHELATASE)		 3t61 GLUCONOKINASE
(Sinorhizobium
meliloti) 		4 / 7 ARG A 103
LEU A 102
PRO A  43
VAL A  89
 None
 1.31A 2hrcA-3t61A:
undetectable		 2hrcA-3t61A:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L7K_A_EDTA739_0
(TEICHOIC ACID
BIOSYNTHESIS PROTEIN
F)		 3t61 GLUCONOKINASE
(Sinorhizobium
meliloti) 		4 / 5 LEU A 175
ARG A 177
ARG A  13
LYS A  13
 None
 1.46A 3l7kA-3t61A:
2.5
3l7kB-3t61A:
2.5		 3l7kA-3t61A:
12.89
3l7kB-3t61A:
12.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RN6_B_15UB301_1
(THROMBIN HEAVY CHAIN)		 3t61 GLUCONOKINASE
(Sinorhizobium
meliloti) 		5 / 12 LEU A 175
LEU A  81
ALA A 106
GLY A  17
GLY A 109
 None
 0.95A 4rn6B-3t61A:
undetectable		 4rn6B-3t61A:
23.73