SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3t69'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FZG_A_SAMA300_0
(16S RRNA METHYLASE)		 3t69 PUTATIVE
2-DEHYDRO-3-DEOXYGAL
ACTONOKINASE
(Sinorhizobium
meliloti) 		5 / 12 THR A  99
GLY A  71
GLY A  74
LEU A 111
VAL A  12
 None
 1.17A 3fzgA-3t69A:
undetectable		 3fzgA-3t69A:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PP7_B_SVRB499_1
(PYRUVATE KINASE)		 3t69 PUTATIVE
2-DEHYDRO-3-DEOXYGAL
ACTONOKINASE
(Sinorhizobium
meliloti) 		5 / 10 THR A  42
HIS A  55
GLY A  54
GLY A  39
ALA A  43
 None
 1.47A 3pp7B-3t69A:
2.7		 3pp7B-3t69A:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_C_ACTC4_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)		 3t69 PUTATIVE
2-DEHYDRO-3-DEOXYGAL
ACTONOKINASE
(Sinorhizobium
meliloti) 		4 / 4 GLY A  71
GLY A 127
THR A 130
LEU A 298
 None
 0.77A 3si7C-3t69A:
undetectable
3si7D-3t69A:
undetectable		 3si7C-3t69A:
20.64
3si7D-3t69A:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_D_ACTD4_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)		 3t69 PUTATIVE
2-DEHYDRO-3-DEOXYGAL
ACTONOKINASE
(Sinorhizobium
meliloti) 		4 / 5 LEU A 298
GLY A  71
GLY A 127
THR A 130
 None
 0.83A 3si7C-3t69A:
undetectable
3si7D-3t69A:
undetectable		 3si7C-3t69A:
20.64
3si7D-3t69A:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3C_A_017A201_2
(HIV-1 PROTEASE)		 3t69 PUTATIVE
2-DEHYDRO-3-DEOXYGAL
ACTONOKINASE
(Sinorhizobium
meliloti) 		5 / 10 ALA A  32
GLY A  25
PRO A  62
ALA A  61
VAL A  59
 None
 0.92A 3t3cB-3t69A:
undetectable		 3t3cB-3t69A:
15.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J6C_A_STRA501_1
(CYTOCHROME P450
MONOOXYGENASE)		 3t69 PUTATIVE
2-DEHYDRO-3-DEOXYGAL
ACTONOKINASE
(Sinorhizobium
meliloti) 		5 / 11 PHE A 194
ALA A 204
ALA A 200
THR A 231
LEU A 184
 None
 1.10A 4j6cA-3t69A:
undetectable		 4j6cA-3t69A:
23.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J6C_B_STRB503_1
(CYTOCHROME P450
MONOOXYGENASE)		 3t69 PUTATIVE
2-DEHYDRO-3-DEOXYGAL
ACTONOKINASE
(Sinorhizobium
meliloti) 		5 / 10 PHE A 194
ALA A 204
ALA A 200
THR A 231
LEU A 184
 None
 1.11A 4j6cB-3t69A:
undetectable		 4j6cB-3t69A:
23.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JBT_A_ASDA501_1
(CYTOCHROME P450
MONOOXYGENASE)		 3t69 PUTATIVE
2-DEHYDRO-3-DEOXYGAL
ACTONOKINASE
(Sinorhizobium
meliloti) 		5 / 12 PHE A 194
ALA A 204
ALA A 200
THR A 231
LEU A 184
 None
 1.11A 4jbtA-3t69A:
undetectable		 4jbtA-3t69A:
23.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JBT_B_ASDB502_1
(CYTOCHROME P450
MONOOXYGENASE)		 3t69 PUTATIVE
2-DEHYDRO-3-DEOXYGAL
ACTONOKINASE
(Sinorhizobium
meliloti) 		5 / 11 PHE A 194
ALA A 204
ALA A 200
THR A 231
LEU A 184
 None
 1.10A 4jbtB-3t69A:
undetectable		 4jbtB-3t69A:
23.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_A_AERA601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3t69 PUTATIVE
2-DEHYDRO-3-DEOXYGAL
ACTONOKINASE
(Sinorhizobium
meliloti) 		5 / 12 LEU A 253
ARG A 209
ALA A 277
VAL A 262
VAL A 285
 None
 1.13A 4nkvA-3t69A:
undetectable		 4nkvA-3t69A:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_C_AERC601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3t69 PUTATIVE
2-DEHYDRO-3-DEOXYGAL
ACTONOKINASE
(Sinorhizobium
meliloti) 		5 / 12 LEU A 253
ARG A 209
ALA A 277
VAL A 262
VAL A 285
 None
 1.13A 4nkvC-3t69A:
undetectable		 4nkvC-3t69A:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_D_AERD601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3t69 PUTATIVE
2-DEHYDRO-3-DEOXYGAL
ACTONOKINASE
(Sinorhizobium
meliloti) 		5 / 12 LEU A 253
ARG A 209
ALA A 277
VAL A 262
VAL A 285
 None
 1.14A 4nkvD-3t69A:
undetectable		 4nkvD-3t69A:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EB5_A_010A609_0
(HNL ISOENZYME 5)		 3t69 PUTATIVE
2-DEHYDRO-3-DEOXYGAL
ACTONOKINASE
(Sinorhizobium
meliloti) 		5 / 11 ALA A  10
ALA A  61
VAL A  59
LEU A  56
HIS A  55
 None
 1.21A 5eb5A-3t69A:
undetectable		 5eb5A-3t69A:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5D_A_SAMA306_0
(METHYLTRANSFERASE)		 3t69 PUTATIVE
2-DEHYDRO-3-DEOXYGAL
ACTONOKINASE
(Sinorhizobium
meliloti) 		5 / 12 ALA A 236
VAL A 188
GLY A 242
ALA A 277
PHE A 175
 None
 0.99A 5n5dA-3t69A:
undetectable		 5n5dA-3t69A:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7Z_A_BHAA201_0
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 3t69 PUTATIVE
2-DEHYDRO-3-DEOXYGAL
ACTONOKINASE
(Sinorhizobium
meliloti) 		4 / 6 LEU A  91
VAL A 163
LEU A 114
VAL A 156
 None
 0.88A 5x7zA-3t69A:
undetectable		 5x7zA-3t69A:
21.75