SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3t6d'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_B_ACTB861_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3t6d PHOTOSYNTHETIC
REACTION CENTER
M-SUBUNIT
(Blastochloris
viridis) 		4 / 5 GLY M 125
TRP M 128
VAL M 131
SER M  54
 LDA  M 705 ( 3.7A)
None
BPB  M 402 ( 4.7A)
SO4  M 325 (-2.9A)
 1.21A 1p6kB-3t6dM:
undetectable		 1p6kB-3t6dM:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_B_ACTB861_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3t6d PHOTOSYNTHETIC
REACTION CENTER
M-SUBUNIT
(Blastochloris
viridis) 		4 / 5 GLY M 125
TRP M 128
VAL M 131
SER M  54
 LDA  M 705 ( 3.7A)
None
BPB  M 402 ( 4.7A)
SO4  M 325 (-2.9A)
 1.22A 1rs6B-3t6dM:
0.7		 1rs6B-3t6dM:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_A_ACTA860_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3t6d PHOTOSYNTHETIC
REACTION CENTER
M-SUBUNIT
(Blastochloris
viridis) 		4 / 5 GLY M 125
TRP M 128
VAL M 131
SER M  54
 LDA  M 705 ( 3.7A)
None
BPB  M 402 ( 4.7A)
SO4  M 325 (-2.9A)
 1.25A 1rs7A-3t6dM:
undetectable		 1rs7A-3t6dM:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_B_ACTB861_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3t6d PHOTOSYNTHETIC
REACTION CENTER
M-SUBUNIT
(Blastochloris
viridis) 		4 / 5 GLY M 125
TRP M 128
VAL M 131
SER M  54
 LDA  M 705 ( 3.7A)
None
BPB  M 402 ( 4.7A)
SO4  M 325 (-2.9A)
 1.21A 1zzuB-3t6dM:
0.7		 1zzuB-3t6dM:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7W_C_SALC1300_1
(LYSR-TYPE REGULATORY
PROTEIN)		 3t6d PHOTOSYNTHETIC
REACTION CENTER
M-SUBUNIT
(Blastochloris
viridis) 		4 / 7 THR M 220
ILE M 221
GLY M 218
HIS M 264
 MQ9  M 501 (-3.5A)
None
None
FE2  M 500 (-3.4A)
 0.83A 2y7wC-3t6dM:
undetectable		 2y7wC-3t6dM:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N62_A_ACTA860_0
(NITRIC OXIDE
SYNTHASE)		 3t6d PHOTOSYNTHETIC
REACTION CENTER
M-SUBUNIT
(Blastochloris
viridis) 		4 / 4 GLY M 125
TRP M 128
VAL M 131
SER M  54
 LDA  M 705 ( 3.7A)
None
BPB  M 402 ( 4.7A)
SO4  M 325 (-2.9A)
 1.23A 3n62A-3t6dM:
0.2		 3n62A-3t6dM:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N65_A_ACTA860_0
(NITRIC OXIDE
SYNTHASE)		 3t6d PHOTOSYNTHETIC
REACTION CENTER
M-SUBUNIT
(Blastochloris
viridis) 		4 / 4 GLY M 125
TRP M 128
VAL M 131
SER M  54
 LDA  M 705 ( 3.7A)
None
BPB  M 402 ( 4.7A)
SO4  M 325 (-2.9A)
 1.23A 3n65A-3t6dM:
undetectable		 3n65A-3t6dM:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N66_A_ACTA860_0
(NITRIC OXIDE
SYNTHASE)		 3t6d PHOTOSYNTHETIC
REACTION CENTER
M-SUBUNIT
(Blastochloris
viridis) 		4 / 4 GLY M 125
TRP M 128
VAL M 131
SER M  54
 LDA  M 705 ( 3.7A)
None
BPB  M 402 ( 4.7A)
SO4  M 325 (-2.9A)
 1.24A 3n66A-3t6dM:
0.1		 3n66A-3t6dM:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BBO_B_ACTB1114_0
(BLR5658 PROTEIN)		 3t6d PHOTOSYNTHETIC
REACTION CENTER
M-SUBUNIT
(Blastochloris
viridis) 		3 / 3 TRP M 199
TRP M 292
THR M 285
 None
 1.47A 4bboB-3t6dM:
undetectable		 4bboB-3t6dM:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWV_A_BCZA513_1
(NEURAMINIDASE)		 3t6d PHOTOSYNTHETIC
REACTION CENTER
M-SUBUNIT
(Blastochloris
viridis) 		3 / 3 ARG M 134
GLU M  22
ARG M  28
 None
 0.86A 4mwvA-3t6dM:
undetectable		 4mwvA-3t6dM:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1806_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3t6d PHOTOSYNTHETIC
REACTION CENTER
M-SUBUNIT
(Blastochloris
viridis) 		4 / 6 ILE M  66
LEU M  67
PHE M  71
PHE M  59
 BPB  M 402 ( 4.4A)
LDA  M 713 ( 4.2A)
NS5  M 600 ( 4.3A)
BPB  M 402 ( 3.7A)
 0.98A 5vkqB-3t6dM:
2.3
5vkqC-3t6dM:
2.3		 5vkqB-3t6dM:
10.82
5vkqC-3t6dM:
10.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1807_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3t6d PHOTOSYNTHETIC
REACTION CENTER
M-SUBUNIT
(Blastochloris
viridis) 		4 / 6 ILE M  66
LEU M  67
PHE M  71
PHE M  59
 BPB  M 402 ( 4.4A)
LDA  M 713 ( 4.2A)
NS5  M 600 ( 4.3A)
BPB  M 402 ( 3.7A)
 0.96A 5vkqC-3t6dM:
2.3
5vkqD-3t6dM:
2.2		 5vkqC-3t6dM:
10.82
5vkqD-3t6dM:
10.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_A_ACTA804_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3t6d PHOTOSYNTHETIC
REACTION CENTER
M-SUBUNIT
(Blastochloris
viridis) 		4 / 5 GLY M 125
TRP M 128
VAL M 131
SER M  54
 LDA  M 705 ( 3.7A)
None
BPB  M 402 ( 4.7A)
SO4  M 325 (-2.9A)
 1.23A 5vunA-3t6dM:
undetectable		 5vunA-3t6dM:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A7J_A_TESA502_0
(CYTOCHROME P450)		 3t6d PHOTOSYNTHETIC
REACTION CENTER
M-SUBUNIT
(Blastochloris
viridis) 		4 / 7 LEU M 212
ALA M 215
ALA M 216
THR M 220
 MQ9  M 501 (-4.7A)
None
MQ9  M 501 ( 4.1A)
MQ9  M 501 (-3.5A)
 0.48A 6a7jA-3t6dM:
undetectable		 6a7jA-3t6dM:
13.44