SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3t6g'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_B_803B311_1
(ANTIGEN CD11A (P180))		 3t6g SH2
DOMAIN-CONTAINING
PROTEIN 3C
(Homo
sapiens) 		4 / 7 VAL A 428
LEU A 514
LEU A 654
LEU A 653
 None
 0.67A 1cqpA-3t6gA:
undetectable
1cqpB-3t6gA:
undetectable		 1cqpA-3t6gA:
19.39
1cqpB-3t6gA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DVT_A_FLPA125_1
(TRANSTHYRETIN)		 3t6g BREAST CANCER
ANTI-ESTROGEN
RESISTANCE PROTEIN 1
(Homo
sapiens) 		4 / 8 LEU B 799
LEU B 822
LEU B 819
SER B 816
 None
 0.96A 1dvtA-3t6gB:
undetectable
1dvtB-3t6gB:
undetectable		 1dvtA-3t6gB:
19.65
1dvtB-3t6gB:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ4_A_CAMA502_0
(CYTOCHROME P450-CAM)		 3t6g SH2
DOMAIN-CONTAINING
PROTEIN 3C
(Homo
sapiens) 		4 / 6 PHE A 586
LEU A 590
VAL A 444
ASP A 441
 None
 0.90A 1dz4A-3t6gA:
undetectable		 1dz4A-3t6gA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ4_B_CAMB502_0
(CYTOCHROME P450-CAM)		 3t6g SH2
DOMAIN-CONTAINING
PROTEIN 3C
(Homo
sapiens) 		4 / 6 PHE A 586
LEU A 590
VAL A 444
ASP A 441
 None
 0.88A 1dz4B-3t6gA:
undetectable		 1dz4B-3t6gA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ6_A_CAMA502_0
(CYTOCHROME P450-CAM)		 3t6g SH2
DOMAIN-CONTAINING
PROTEIN 3C
(Homo
sapiens) 		4 / 5 PHE A 586
LEU A 590
VAL A 444
ASP A 441
 None
 0.89A 1dz6A-3t6gA:
undetectable		 1dz6A-3t6gA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FXV_B_PNNB1001_0
(PENICILLIN ACYLASE)		 3t6g BREAST CANCER
ANTI-ESTROGEN
RESISTANCE PROTEIN 1
(Homo
sapiens) 		4 / 7 SER B 782
SER B 839
ALA B 843
PHE B 778
 None
 1.17A 1fxvA-3t6gB:
undetectable
1fxvB-3t6gB:
undetectable		 1fxvA-3t6gB:
23.24
1fxvB-3t6gB:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IBG_H_OBNH1_1
(IGG2B-KAPPA 40-50
FAB (HEAVY CHAIN))		 3t6g BREAST CANCER
ANTI-ESTROGEN
RESISTANCE PROTEIN 1
SH2
DOMAIN-CONTAINING
PROTEIN 3C
(Homo
sapiens) 		4 / 6 HIS B 790
LEU A 623
PHE B 794
VAL B 793
 None
 1.17A 1ibgH-3t6gB:
undetectable		 1ibgH-3t6gB:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IWI_A_CAMA418_0
(CYTOCHROME P450-CAM)		 3t6g SH2
DOMAIN-CONTAINING
PROTEIN 3C
(Homo
sapiens) 		4 / 8 PHE A 586
LEU A 590
VAL A 444
ASP A 441
 None
 0.95A 1iwiA-3t6gA:
undetectable		 1iwiA-3t6gA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1O76_B_CAMB1420_0
(CYTOCHROME P450-CAM)		 3t6g SH2
DOMAIN-CONTAINING
PROTEIN 3C
(Homo
sapiens) 		4 / 8 PHE A 586
LEU A 590
VAL A 444
ASP A 441
 None
 0.95A 1o76B-3t6gA:
undetectable		 1o76B-3t6gA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T85_A_CAMA422_0
(CYTOCHROME P450-CAM)		 3t6g SH2
DOMAIN-CONTAINING
PROTEIN 3C
(Homo
sapiens) 		4 / 7 PHE A 586
LEU A 590
VAL A 444
ASP A 441
 None
 0.89A 1t85A-3t6gA:
undetectable		 1t85A-3t6gA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T87_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 3t6g SH2
DOMAIN-CONTAINING
PROTEIN 3C
(Homo
sapiens) 		4 / 7 PHE A 586
LEU A 590
VAL A 444
ASP A 441
 None
 0.95A 1t87A-3t6gA:
undetectable		 1t87A-3t6gA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T88_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 3t6g SH2
DOMAIN-CONTAINING
PROTEIN 3C
(Homo
sapiens) 		4 / 7 PHE A 586
LEU A 590
VAL A 444
ASP A 441
 None
 0.88A 1t88A-3t6gA:
undetectable		 1t88A-3t6gA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TV8_B_SAMB2501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 3t6g BREAST CANCER
ANTI-ESTROGEN
RESISTANCE PROTEIN 1
(Homo
sapiens) 		4 / 7 THR B 829
THR B 830
SER B 782
VAL B 762
 None
 1.16A 1tv8B-3t6gB:
undetectable		 1tv8B-3t6gB:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UYU_A_CAMA1416_0
(CYTOCHROME P450-CAM)		 3t6g SH2
DOMAIN-CONTAINING
PROTEIN 3C
(Homo
sapiens) 		4 / 8 PHE A 586
LEU A 590
VAL A 444
ASP A 441
 None
 0.89A 1uyuA-3t6gA:
undetectable		 1uyuA-3t6gA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y7I_A_SALA502_1
(SALICYLIC
ACID-BINDING PROTEIN
2)		 3t6g SH2
DOMAIN-CONTAINING
PROTEIN 3C
(Homo
sapiens) 		3 / 3 LEU A 654
HIS A 436
LYS A 439
 None
 1.12A 1y7iA-3t6gA:
undetectable		 1y7iA-3t6gA:
26.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YRC_A_CAMA420_0
(CYTOCHROME P450-CAM)		 3t6g SH2
DOMAIN-CONTAINING
PROTEIN 3C
(Homo
sapiens) 		4 / 7 PHE A 586
LEU A 590
VAL A 444
ASP A 441
 None
 0.91A 1yrcA-3t6gA:
undetectable		 1yrcA-3t6gA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YRD_A_CAMA420_0
(CYTOCHROME P450-CAM)		 3t6g SH2
DOMAIN-CONTAINING
PROTEIN 3C
(Homo
sapiens) 		4 / 7 PHE A 586
LEU A 590
VAL A 444
ASP A 441
 None
 0.93A 1yrdA-3t6gA:
undetectable		 1yrdA-3t6gA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1O_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 3t6g SH2
DOMAIN-CONTAINING
PROTEIN 3C
(Homo
sapiens) 		4 / 8 PHE A 586
LEU A 590
VAL A 444
ASP A 441
 None
 0.91A 2a1oA-3t6gA:
undetectable		 2a1oA-3t6gA:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CPP_A_CAMA422_0
(CYTOCHROME P450-CAM)		 3t6g SH2
DOMAIN-CONTAINING
PROTEIN 3C
(Homo
sapiens) 		4 / 7 PHE A 586
LEU A 590
VAL A 444
ASP A 441
 None
 0.94A 2cppA-3t6gA:
undetectable		 2cppA-3t6gA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FEU_B_CAMB1421_0
(CYTOCHROME P450-CAM)		 3t6g SH2
DOMAIN-CONTAINING
PROTEIN 3C
(Homo
sapiens) 		4 / 7 PHE A 586
LEU A 590
VAL A 444
ASP A 441
 None
 0.93A 2feuB-3t6gA:
undetectable		 2feuB-3t6gA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KCE_B_D16B568_1
(THYMIDYLATE SYNTHASE)		 3t6g SH2
DOMAIN-CONTAINING
PROTEIN 3C
(Homo
sapiens) 		5 / 12 HIS A 436
LEU A 666
ASP A 493
LEU A 425
VAL A 421
 None
 1.21A 2kceB-3t6gA:
undetectable		 2kceB-3t6gA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBL_A_CAMA517_0
(CYTOCHROME P450-CAM)		 3t6g SH2
DOMAIN-CONTAINING
PROTEIN 3C
(Homo
sapiens) 		4 / 7 PHE A 586
LEU A 590
VAL A 444
ASP A 441
 None
 0.96A 2qblA-3t6gA:
undetectable		 2qblA-3t6gA:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_A_DIFA1376_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 3t6g BREAST CANCER
ANTI-ESTROGEN
RESISTANCE PROTEIN 1
(Homo
sapiens) 		4 / 8 TYR B 747
LEU B 744
LEU B 799
ALA B 803
 None
 1.09A 2wekA-3t6gB:
undetectable		 2wekA-3t6gB:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZAW_A_CAMA422_0
(CYTOCHROME P450-CAM)		 3t6g SH2
DOMAIN-CONTAINING
PROTEIN 3C
(Homo
sapiens) 		4 / 6 PHE A 586
LEU A 590
VAL A 444
ASP A 441
 None
 0.97A 2zawA-3t6gA:
undetectable		 2zawA-3t6gA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZAX_A_CAMA422_0
(CYTOCHROME P450-CAM)		 3t6g SH2
DOMAIN-CONTAINING
PROTEIN 3C
(Homo
sapiens) 		4 / 7 PHE A 586
LEU A 590
VAL A 444
ASP A 441
 None
 0.92A 2zaxA-3t6gA:
undetectable		 2zaxA-3t6gA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWT_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 3t6g SH2
DOMAIN-CONTAINING
PROTEIN 3C
(Homo
sapiens) 		4 / 7 PHE A 586
LEU A 590
VAL A 444
ASP A 441
 None
 0.91A 2zwtA-3t6gA:
undetectable		 2zwtA-3t6gA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWU_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 3t6g SH2
DOMAIN-CONTAINING
PROTEIN 3C
(Homo
sapiens) 		4 / 7 PHE A 586
LEU A 590
VAL A 444
ASP A 441
 None
 0.91A 2zwuA-3t6gA:
undetectable		 2zwuA-3t6gA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		 3t6g BREAST CANCER
ANTI-ESTROGEN
RESISTANCE PROTEIN 1
SH2
DOMAIN-CONTAINING
PROTEIN 3C
(Homo
sapiens) 		4 / 8 LEU A 623
ILE B 786
ARG B 824
GLY B 825
 None
 0.94A 3b9lA-3t6gA:
undetectable		 3b9lA-3t6gA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWF_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 3t6g SH2
DOMAIN-CONTAINING
PROTEIN 3C
(Homo
sapiens) 		4 / 7 PHE A 586
LEU A 590
VAL A 444
ASP A 441
 None
 0.91A 3fwfA-3t6gA:
undetectable		 3fwfA-3t6gA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWF_B_CAMB420_0
(CAMPHOR
5-MONOOXYGENASE)		 3t6g SH2
DOMAIN-CONTAINING
PROTEIN 3C
(Homo
sapiens) 		4 / 7 PHE A 586
LEU A 590
VAL A 444
ASP A 441
 None
 0.92A 3fwfB-3t6gA:
undetectable		 3fwfB-3t6gA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWG_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 3t6g SH2
DOMAIN-CONTAINING
PROTEIN 3C
(Homo
sapiens) 		4 / 6 PHE A 586
LEU A 590
VAL A 444
ASP A 441
 None
 0.89A 3fwgA-3t6gA:
undetectable		 3fwgA-3t6gA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWG_B_CAMB420_0
(CAMPHOR
5-MONOOXYGENASE)		 3t6g SH2
DOMAIN-CONTAINING
PROTEIN 3C
(Homo
sapiens) 		4 / 7 PHE A 586
LEU A 590
VAL A 444
ASP A 441
 None
 0.89A 3fwgB-3t6gA:
undetectable		 3fwgB-3t6gA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWJ_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 3t6g SH2
DOMAIN-CONTAINING
PROTEIN 3C
(Homo
sapiens) 		4 / 7 PHE A 586
LEU A 590
VAL A 444
ASP A 441
 None
 0.92A 3fwjA-3t6gA:
undetectable		 3fwjA-3t6gA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L63_A_CAMA440_0
(CAMPHOR
5-MONOOXYGENASE)		 3t6g SH2
DOMAIN-CONTAINING
PROTEIN 3C
(Homo
sapiens) 		4 / 7 PHE A 586
LEU A 590
VAL A 444
ASP A 441
 None
 0.93A 3l63A-3t6gA:
undetectable		 3l63A-3t6gA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LOQ_A_ACTA277_0
(UNIVERSAL STRESS
PROTEIN)		 3t6g SH2
DOMAIN-CONTAINING
PROTEIN 3C
(Homo
sapiens) 		3 / 3 ASP A 478
SER A 395
ARG A 446
 None
 0.96A 3loqA-3t6gA:
undetectable		 3loqA-3t6gA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R55_A_PZAA598_0
(LACTOPEROXIDASE)		 3t6g SH2
DOMAIN-CONTAINING
PROTEIN 3C
(Homo
sapiens) 		3 / 3 GLU A 481
PHE A 396
GLN A 662
 None
 0.98A 3r55A-3t6gA:
undetectable		 3r55A-3t6gA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQW_C_ACHC323_0
(ELIC PENTAMERIC
LIGAND GATED ION
CHANNEL FROM ERWINIA
CHRYSANTHEMI)		 3t6g SH2
DOMAIN-CONTAINING
PROTEIN 3C
(Homo
sapiens) 		4 / 8 GLU A 652
GLU A 655
LEU A 417
PHE A 661
 None
 1.13A 3rqwC-3t6gA:
undetectable
3rqwD-3t6gA:
undetectable		 3rqwC-3t6gA:
20.56
3rqwD-3t6gA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQW_J_ACHJ323_0
(ELIC PENTAMERIC
LIGAND GATED ION
CHANNEL FROM ERWINIA
CHRYSANTHEMI)		 3t6g SH2
DOMAIN-CONTAINING
PROTEIN 3C
(Homo
sapiens) 		4 / 8 GLU A 652
GLU A 655
LEU A 417
PHE A 661
 None
 1.13A 3rqwF-3t6gA:
undetectable
3rqwJ-3t6gA:
undetectable		 3rqwF-3t6gA:
20.56
3rqwJ-3t6gA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRH_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 3t6g SH2
DOMAIN-CONTAINING
PROTEIN 3C
(Homo
sapiens) 		4 / 7 PHE A 586
LEU A 590
VAL A 444
ASP A 441
 None
 0.90A 3wrhA-3t6gA:
undetectable		 3wrhA-3t6gA:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRH_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)		 3t6g SH2
DOMAIN-CONTAINING
PROTEIN 3C
(Homo
sapiens) 		4 / 6 PHE A 586
LEU A 590
VAL A 444
ASP A 441
 None
 0.91A 3wrhE-3t6gA:
undetectable		 3wrhE-3t6gA:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRJ_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 3t6g SH2
DOMAIN-CONTAINING
PROTEIN 3C
(Homo
sapiens) 		4 / 7 PHE A 586
LEU A 590
VAL A 444
ASP A 441
 None
 0.91A 3wrjA-3t6gA:
undetectable		 3wrjA-3t6gA:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRJ_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)		 3t6g SH2
DOMAIN-CONTAINING
PROTEIN 3C
(Homo
sapiens) 		4 / 6 PHE A 586
LEU A 590
VAL A 444
ASP A 441
 None
 0.91A 3wrjE-3t6gA:
undetectable		 3wrjE-3t6gA:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRL_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 3t6g SH2
DOMAIN-CONTAINING
PROTEIN 3C
(Homo
sapiens) 		4 / 7 PHE A 586
LEU A 590
VAL A 444
ASP A 441
 None
 0.91A 3wrlA-3t6gA:
undetectable		 3wrlA-3t6gA:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRL_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)		 3t6g SH2
DOMAIN-CONTAINING
PROTEIN 3C
(Homo
sapiens) 		4 / 7 PHE A 586
LEU A 590
VAL A 444
ASP A 441
 None
 0.95A 3wrlE-3t6gA:
undetectable		 3wrlE-3t6gA:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRM_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 3t6g SH2
DOMAIN-CONTAINING
PROTEIN 3C
(Homo
sapiens) 		4 / 7 PHE A 586
LEU A 590
VAL A 444
ASP A 441
 None
 0.92A 3wrmA-3t6gA:
undetectable		 3wrmA-3t6gA:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRM_F_CAMF503_0
(CAMPHOR
5-MONOOXYGENASE)		 3t6g SH2
DOMAIN-CONTAINING
PROTEIN 3C
(Homo
sapiens) 		4 / 7 PHE A 586
LEU A 590
VAL A 444
ASP A 441
 None
 0.92A 3wrmF-3t6gA:
undetectable		 3wrmF-3t6gA:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A9J_B_TYLB1187_1
(BROMODOMAIN
CONTAINING 2)		 3t6g SH2
DOMAIN-CONTAINING
PROTEIN 3C
(Homo
sapiens) 		4 / 5 VAL A 589
LEU A 467
LEU A 479
ILE A 447
 None
 0.92A 4a9jB-3t6gA:
undetectable		 4a9jB-3t6gA:
16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CP4_A_CAMA416_0
(CYTOCHROME P450-CAM)		 3t6g SH2
DOMAIN-CONTAINING
PROTEIN 3C
(Homo
sapiens) 		4 / 7 PHE A 586
LEU A 590
VAL A 444
ASP A 441
 None
 0.95A 4cp4A-3t6gA:
undetectable		 4cp4A-3t6gA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EK1_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 3t6g SH2
DOMAIN-CONTAINING
PROTEIN 3C
(Homo
sapiens) 		4 / 6 PHE A 586
LEU A 590
VAL A 444
ASP A 441
 None
 0.95A 4ek1A-3t6gA:
undetectable		 4ek1A-3t6gA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G3R_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 3t6g SH2
DOMAIN-CONTAINING
PROTEIN 3C
(Homo
sapiens) 		4 / 6 PHE A 586
LEU A 590
VAL A 444
ASP A 441
 None
 0.91A 4g3rA-3t6gA:
undetectable		 4g3rA-3t6gA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G3R_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 3t6g SH2
DOMAIN-CONTAINING
PROTEIN 3C
(Homo
sapiens) 		4 / 6 PHE A 586
LEU A 590
VAL A 444
ASP A 441
 None
 0.95A 4g3rB-3t6gA:
undetectable		 4g3rB-3t6gA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KKY_X_CAMX503_0
(CAMPHOR
5-MONOOXYGENASE)		 3t6g SH2
DOMAIN-CONTAINING
PROTEIN 3C
(Homo
sapiens) 		4 / 6 PHE A 586
LEU A 590
VAL A 444
ASP A 441
 None
 0.89A 4kkyX-3t6gA:
undetectable		 4kkyX-3t6gA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4A_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 3t6g SH2
DOMAIN-CONTAINING
PROTEIN 3C
(Homo
sapiens) 		4 / 8 PHE A 586
LEU A 590
VAL A 444
ASP A 441
 None
 0.94A 4l4aA-3t6gA:
undetectable		 4l4aA-3t6gA:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4C_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 3t6g SH2
DOMAIN-CONTAINING
PROTEIN 3C
(Homo
sapiens) 		4 / 6 PHE A 586
LEU A 590
VAL A 444
ASP A 441
 None
 0.88A 4l4cA-3t6gA:
undetectable		 4l4cA-3t6gA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4E_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 3t6g SH2
DOMAIN-CONTAINING
PROTEIN 3C
(Homo
sapiens) 		4 / 8 PHE A 586
LEU A 590
VAL A 444
ASP A 441
 None
 0.94A 4l4eA-3t6gA:
undetectable		 4l4eA-3t6gA:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4F_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 3t6g SH2
DOMAIN-CONTAINING
PROTEIN 3C
(Homo
sapiens) 		4 / 8 PHE A 586
LEU A 590
VAL A 444
ASP A 441
 None
 0.94A 4l4fA-3t6gA:
undetectable		 4l4fA-3t6gA:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4G_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 3t6g SH2
DOMAIN-CONTAINING
PROTEIN 3C
(Homo
sapiens) 		4 / 7 PHE A 586
LEU A 590
VAL A 444
ASP A 441
 None
 0.89A 4l4gA-3t6gA:
undetectable		 4l4gA-3t6gA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1I_D_LOCD502_1
(TUBULIN BETA CHAIN)		 3t6g SH2
DOMAIN-CONTAINING
PROTEIN 3C
(Homo
sapiens) 		5 / 12 LEU A 507
LEU A 535
LEU A 490
MET A 486
ALA A 515
 None
 1.14A 4x1iD-3t6gA:
undetectable		 4x1iD-3t6gA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H1E_A_VDXA501_1
(VITAMIN D3 RECEPTOR)		 3t6g SH2
DOMAIN-CONTAINING
PROTEIN 3C
(Homo
sapiens) 		5 / 12 LEU A 495
SER A 691
ARG A 542
SER A 541
HIS A 484
 None
 1.33A 5h1eA-3t6gA:
undetectable		 5h1eA-3t6gA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_B_SAMB501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 3t6g SH2
DOMAIN-CONTAINING
PROTEIN 3C
(Homo
sapiens) 		3 / 3 SER A 500
ALA A 501
THR A 549
 None
 0.71A 5n0xB-3t6gA:
undetectable		 5n0xB-3t6gA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WK9_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 3t6g SH2
DOMAIN-CONTAINING
PROTEIN 3C
(Homo
sapiens) 		4 / 7 PHE A 586
LEU A 590
VAL A 444
ASP A 441
 None
 0.93A 5wk9A-3t6gA:
undetectable		 5wk9A-3t6gA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZW2_A_ACTA511_0
(L-PROLYL-[PEPTIDYL-C
ARRIER PROTEIN]
DEHYDROGENASE)		 3t6g SH2
DOMAIN-CONTAINING
PROTEIN 3C
(Homo
sapiens) 		3 / 3 ARG A 504
ILE A 494
SER A 497
 None
 0.72A 5zw2A-3t6gA:
undetectable		 5zw2A-3t6gA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CP4_A_CAMA422_0
(CYTOCHROME P450CAM)		 3t6g SH2
DOMAIN-CONTAINING
PROTEIN 3C
(Homo
sapiens) 		4 / 8 PHE A 586
LEU A 590
VAL A 444
ASP A 441
 None
 0.90A 6cp4A-3t6gA:
undetectable		 6cp4A-3t6gA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_A_DCFA401_1
(ADENOSINE DEAMINASE)		 3t6g SH2
DOMAIN-CONTAINING
PROTEIN 3C
BREAST CANCER
ANTI-ESTROGEN
RESISTANCE PROTEIN 1
(Homo
sapiens;
Homo
sapiens) 		4 / 4 HIS B 790
LEU A 469
TYR B 747
GLY B 796
 None
 1.34A 6n91A-3t6gB:
undetectable		 6n91A-3t6gB:
18.22